{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T00:18:50Z","timestamp":1710807530962},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Interictal occipital epileptiform abnormalities have not been well characterized. The objective of this pilot study was to assess their significance in children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A search was performed on the EEG database for the keywords \u201coccipital\u201d, \u201cspike\u201d, \u201csharp wave\u201d and \u201cepileptiform\u201d. Patients were divided into two groups based on the absence of all (group 1) or presence of any (group 2) of the following criteria: mental retardation, cerebral palsy, neurological deficits, abnormal MRI and\/or intractable epilepsy. Special attention was given to the spike\/sharp wave amplitude\/duration and background slowing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 44 children (eight months to 15 years) were studied. Groups 1 and 2 were each composed of 22 children. Background slowing was more frequent in group 2 (10\/22, 45%) compared to group 1 (1\/22, 4.5%; p = 0.002). In group 2, 8\/22 (36%) had spikes or sharp waves with amplitudes below 50 \u03bcV or above 150 \u03bcV with a positive predictive value of 89%, and a negative predictive value of 39%. Only 1\/22 (4.5%) in group 1 had epileptiform activity outside of the 50\u2010150 \u03bcV range.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The presence of very high or low\u2010amplitude occipital epileptiform abnormalities or background slowing may be indicative of encephalopathy.<\/jats:p><\/jats:sec>","DOI":"10.1684\/epd.2010.0296","type":"journal-article","created":{"date-parts":[[2019,8,2]],"date-time":"2019-08-02T13:24:19Z","timestamp":1564752259000},"page":"59-64","source":"Crossref","is-referenced-by-count":0,"title":["Significance of interictal occipital epileptiform discharges in children"],"prefix":"10.1002","volume":"12","author":[{"given":"Chunyang","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Neurology Hahnemann University Hospital Philadelphia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divya S.","family":"Khurana","sequence":"additional","affiliation":[{"name":"Section of Neurology St. Christopher's Hospital for Children Department of Pediatrics Drexel University College of Medicine Philadelphia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeev V.","family":"Kothare","sequence":"additional","affiliation":[{"name":"Section of Neurology St. Christopher's Hospital for Children Department of Pediatrics Drexel University College of Medicine Philadelphia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agustin","family":"Legido","sequence":"additional","affiliation":[{"name":"Section of Neurology St. Christopher's Hospital for Children Department of Pediatrics Drexel University College of Medicine Philadelphia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geoffrey","family":"Harrison","sequence":"additional","affiliation":[{"name":"Section of Neurology St. Christopher's Hospital for Children Department of Pediatrics Drexel University College of Medicine Philadelphia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen S.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Section of Neurology St. Christopher's Hospital for Children Department of Pediatrics Drexel University College of Medicine Philadelphia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Valencia","sequence":"additional","affiliation":[{"name":"Section of Neurology St. Christopher's Hospital for Children Department of Pediatrics Drexel University College of Medicine Philadelphia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,3]]},"reference":[{"key":"e_1_2_5_2_1","volume-title":"The epileptic seizure: its functional morphology and diagnostic significance","author":"Ajmone\u2010Marsan 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