{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T11:07:51Z","timestamp":1769598471828,"version":"3.49.0"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Reflex seizures are a rare phenomenon among epileptic patients, in which an epileptic discharge is triggered by various kinds of stimuli (visual, auditory, tactile or gustatory). Epilepsy is common in Rett syndrome patients (up to 70%), but to the authors' knowledge, no pressure or eating\u2010triggered seizures have yet been reported in Rett children. We describe three epileptic Rett patients with reflex seizures, triggered by food intake or proprioception. One patient with congenital Rett Sd. developed infantile epileptic spasms at around seven months and two patients with classic Rett Sd. presented with generalised tonic\u2010clonic seizures at around five years. Reflex seizures appeared when the patients were teenagers. The congenital\u2010Rett patient presented eating\u2010triggered seizures at the beginning of almost every meal, demonstrated by EEG recording. Both classic Rett patients showed self\u2010provoked pressure \u2010triggered attacks, influenced by stress or excitement. Non\u2010triggered seizures were controlled with carbamazepine or valproate, but reflex seizures did not respond to antiepileptic drugs. Risperidone partially improved self\u2010provoked seizures. When reflex seizures are suspected, reproducing the trigger during EEG recording is fundamental; however, self\u2010provoked seizures depend largely on the patient's will. Optimal therapy (though not always possible) consists of avoiding the trigger. Stress modifiers such as risperidone may help control self\u2010provoked seizures.<\/jats:p>","DOI":"10.1684\/epd.2011.0475","type":"journal-article","created":{"date-parts":[[2019,8,2]],"date-time":"2019-08-02T13:24:19Z","timestamp":1564752259000},"page":"389-393","source":"Crossref","is-referenced-by-count":20,"title":["Reflex seizures in Rett syndrome"],"prefix":"10.1002","volume":"13","author":[{"given":"Ana Roche","family":"Mart\u00ednez","sequence":"first","affiliation":[{"name":"Department of Child Neurology Fundaci\u00f3n Hospital Sant Joan de D\u00e9u of Barcelona and CIBERER Sant Joan de D\u00e9u Children's Hospital of Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M Itziar Alonso","family":"Colmenero","sequence":"additional","affiliation":[{"name":"Department of Child Neurology Clinical Neurophysiology Unit Sant Joan de D\u00e9u Children's Hospital of Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreia Gomes","family":"Pereira","sequence":"additional","affiliation":[{"name":"Department of Child Neurology Fundaci\u00f3n Hospital Sant Joan de D\u00e9u of Barcelona and CIBERER Sant Joan de D\u00e9u Children's Hospital of Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesc X Sanmart\u00ed","family":"Vilaplana","sequence":"additional","affiliation":[{"name":"Department of Child Neurology Clinical Neurophysiology Unit Sant Joan de D\u00e9u Children's Hospital of Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith Armstrong","family":"Mor\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology Fundaci\u00f3n Hospital Sant Joan de D\u00e9u of Barcelona and CIBERER Sant Joan de D\u00e9u Children's Hospital of Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merc\u00e9 Pineda","family":"Marfa","sequence":"additional","affiliation":[{"name":"Department of Child Neurology Fundaci\u00f3n Hospital Sant Joan de D\u00e9u of Barcelona and CIBERER Sant Joan de D\u00e9u Children's Hospital of Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00314493"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10048-009-0220-2"},{"key":"e_1_2_5_4_1","first-page":"155","article-title":"\u00e9pilepsie temporale r\u00e9flexe chez un jeune enfant","volume":"89","author":"Boudouresques J","year":"1953","journal-title":"Rev Neurol (Paris)"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2009.02278.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000116258"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1992.tb01701.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410140412"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1684\/j.1950-6945.2000.tb00362.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22124"},{"key":"e_1_2_5_11_1","volume-title":"The Epilepsies: Seizures, Syndromes and Management","author":"Panayiotopoulos CP","year":"2005"},{"key":"e_1_2_5_12_1","first-page":"227","article-title":"Seizures induced by eating","volume":"75","author":"R\u00e9millard GM","year":"1998","journal-title":"Adv Neurol"}],"container-title":["Epileptic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1684\/epd.2011.0475","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T16:21:45Z","timestamp":1710778905000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1684\/epd.2011.0475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["10.1684\/epd.2011.0475"],"URL":"https:\/\/doi.org\/10.1684\/epd.2011.0475","archive":["Portico"],"relation":{},"ISSN":["1294-9361","1950-6945"],"issn-type":[{"value":"1294-9361","type":"print"},{"value":"1950-6945","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12]]}}}