{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T10:56:11Z","timestamp":1759056971085},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Background.<\/jats:italic> The lack of specific MRI abnormalities in anti\u2010NMDA receptor encephalitis makes the identification of the most affected areas difficult. Functional neuroimaging could be useful to identify brain dysfunction associated with psychiatric symptoms, but few precise data are available up to now. <jats:italic>Case study.<\/jats:italic> A 27\u2010year\u2010old woman was referred for recent behavioural changes and jerks of the right foot. Serial left fronto\u2010temporal seizures were recorded. Identification of anti\u2010NMDA receptor antibodies in CSF indicated a diagnosis of anti\u2010NMDA receptor encephalitis. Two foci of hypermetabolism, in the left prefrontal cortex and the anterior cingulate cortex, were identified using 18\u2010fluorodeoxyglucose PET and both disappeared after treatment. Brain MRI was normal, except for a mild left prefrontal hypersignal. <jats:italic>Conclusions.<\/jats:italic> The increase in marker uptake in motor and premotor regions in our case probably corresponds to epileptic activity. Our data suggest that the anterior cingulate cortex could play an important role in psychiatric symptoms. Other studies are needed to better understand the pathophysiology of anti\u2010NMDA receptor encephalitis.<\/jats:p>","DOI":"10.1684\/epd.2012.0486","type":"journal-article","created":{"date-parts":[[2019,8,2]],"date-time":"2019-08-02T13:24:19Z","timestamp":1564752259000},"page":"90-93","source":"Crossref","is-referenced-by-count":13,"title":["PET follow\u2010up in a case of anti\u2010NMDAR encephalitis: arguments for cingulate limbic encephalitis"],"prefix":"10.1002","volume":"14","author":[{"given":"Jean\u2010Baptiste","family":"Chanson","sequence":"first","affiliation":[{"name":"D\u00e9partement de Neurologie CHRU de Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihaela","family":"Diaconu","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Neurologie CHRU de Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9r\u00f4me","family":"Honnorat","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon H\u00f4pital Neurologique Centre de R\u00e9f\u00e9rence Maladies Rares \u201cSyndromes Neurologiques Paran\u00e9oplasiques\u201d Lyon France"},{"name":"Lyon Neuroscience Research Center INSERM U 1028 \/ CNRS UMR 5292 Universit\u00e9 de Lyon\u2010Universit\u00e9 Claude Bernard Lyon 1 Facult\u00e9 Laennec Lyon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Martin","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne et d'Immunologie Clinique CHRU de Strasbourg"},{"name":"UPR CNRS 9021 Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9r\u00f4me","family":"De Seze","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Neurologie CHRU de Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izzie\u2010Jacques","family":"Namer","sequence":"additional","affiliation":[{"name":"Service de Biophysique et M\u00e9decine Nucl\u00e9aire CHRU de Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edouard","family":"Hirsch","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Neurologie CHRU de Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10713"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21050"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70253-2"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.7.1481"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0167-10.2010"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000278388.90370.c3"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70137-X"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-5-31"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5674-5"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0b013e3181db4d4a"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2010.07349.x"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2010.03.002"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2010.04.019"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-977X(96)00039-9"}],"container-title":["Epileptic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1684\/epd.2012.0486","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T16:21:17Z","timestamp":1710778877000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1684\/epd.2012.0486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["10.1684\/epd.2012.0486"],"URL":"https:\/\/doi.org\/10.1684\/epd.2012.0486","archive":["Portico"],"relation":{},"ISSN":["1294-9361","1950-6945"],"issn-type":[{"value":"1294-9361","type":"print"},{"value":"1950-6945","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}