{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:33:52Z","timestamp":1761514432679},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>We present the first reported case of a rapid clinical and electroencephalographic response to intravenous levetiracetam infusion of myoclonic status epilepticus in a patient with progressive myoclonus epilepsy due to Gaucher disease. Under continuous video\u2010EEG monitoring, the clinical myoclonic status and the electrographic ictal discharges resolved within 10 minutes after the infusion was initiated. The patient tolerated the treatment well without any reported side effects. This case suggests that levetiracetam may be a safe, effective, and well tolerated intravenous drug in patients with metabolic myoclonic status epilepticus such as Gaucher disease.<\/jats:p>","DOI":"10.1684\/epd.2012.0501","type":"journal-article","created":{"date-parts":[[2019,8,2]],"date-time":"2019-08-02T13:24:19Z","timestamp":1564752259000},"page":"155-158","source":"Crossref","is-referenced-by-count":10,"title":["Gaucher disease: successful treatment of myoclonic status epilepticus with levetiracetam"],"prefix":"10.1002","volume":"14","author":[{"given":"Guadalupe Fernandez\u2010Baca","family":"Vaca","sequence":"first","affiliation":[{"name":"Epilepsy Center Neurological Institute University Hospitals Case Medical Center Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Lenz","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University Hospitals Case Medical Center Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elia M Pestana","family":"Knight","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Epilepsy Rainbow Babies and Children's Hospital Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingrid","family":"Tuxhorn","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Epilepsy Rainbow Babies and Children's Hospital Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e3181a0e1cf"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073807309237"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(65)90743-6"},{"key":"e_1_2_7_5_1","first-page":"41","article-title":"Myoclonus in Gaucher Disease","volume":"89","author":"Frei KP","year":"2002","journal-title":"Adv Neurol"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1684\/j.1950-6945.2000.tb00445.x","article-title":"Antimyoclonic effect of levetiracetam","volume":"2","author":"Genton P","year":"2000","journal-title":"Epileptic Disord"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000217916.00225.3a"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2007.11.003"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1592\/phco.21.17.1375.34432"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2008.01546.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2005.11.021"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2009.02.010"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.30.2.152"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-006-9039-1"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/08830738050200020101"}],"container-title":["Epileptic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1684\/epd.2012.0501","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T16:54:09Z","timestamp":1721580849000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1684\/epd.2012.0501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1684\/epd.2012.0501"],"URL":"https:\/\/doi.org\/10.1684\/epd.2012.0501","archive":["Portico"],"relation":{},"ISSN":["1294-9361","1950-6945"],"issn-type":[{"value":"1294-9361","type":"print"},{"value":"1950-6945","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}