{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T21:34:31Z","timestamp":1790026471611,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,6,18]],"date-time":"2014-06-18T00:00:00Z","timestamp":1403049600000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:p><jats:italic>Aim<\/jats:italic>. Panayiotopoulos syndrome (PS) is an age\u2010related seizure susceptibility syndrome that affects the central autonomic system. Although the majority of the few ictal recordings obtained so far suggest an occipital origin, semiological and interictal EEG data appear to favour more extensive involvement. In this study, the characteristics (including those based on semiology and EEG) of children with Panayiotopoulos syndrome (<jats:italic>n<\/jats:italic>=24) and those with lesion\u2010related, symptomatic occipital lobe epilepsy (SOLE) (<jats:italic>n<\/jats:italic>=23) were compared.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>. Detailed semiological information and EEG parameters including the localisation, distribution, density (n\/sec), reactivity, and morphological characteristics of spike\u2010wave foci and their relationship with different states of vigilance were compared between the two groups.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>. The age at seizure onset was significantly younger in patients with symptomatic occipital lobe epilepsy than in those with PS (mean age at onset: 3.4 <jats:italic>versus<\/jats:italic> 5.6 years, respectively; <jats:italic>p<\/jats:italic>=0.044). Autonomic seizures (<jats:italic>p<\/jats:italic>=0.001) and ictal syncope (<jats:italic>p<\/jats:italic>=0.055) were more frequent in PS than in symptomatic occipital lobe epilepsy (87.5% and 37.5% <jats:italic>versus<\/jats:italic> 43.5% and 13%, respectively). The interictal spike\u2010wave activity increased significantly during non\u2010rapid eye movement (non\u2010REM) sleep in both groups. The spike waves in non\u2010REM seen in PS tended to spread mainly to central and centro\u2010temporal regions.<\/jats:p><jats:p><jats:italic>Conclusions<\/jats:italic>. The results indicate that although common features do exist, Panayiotopoulos syndrome differs from symptomatic occipital lobe epilepsy and has a unique low epileptogenic threshold related to particular brain circuits.<\/jats:p>","DOI":"10.1684\/epd.2014.0652","type":"journal-article","created":{"date-parts":[[2019,8,2]],"date-time":"2019-08-02T13:24:44Z","timestamp":1564752284000},"page":"197-202","source":"Crossref","is-referenced-by-count":13,"title":["Panayiotopoulos syndrome and symptomatic occipital lobe epilepsy of childhood: a clinical and EEG study"],"prefix":"10.1002","volume":"16","author":[{"given":"Gulten","family":"Tata","sequence":"first","affiliation":[{"name":"Department of Neurology Ozel Yeni Iklim Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betul Tekin","family":"Guveli","sequence":"additional","affiliation":[{"name":"Bakirkoy Mazhar Osman Research\u2010Training 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