{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T08:41:27Z","timestamp":1790498487085,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,1,13]],"date-time":"2015-01-13T00:00:00Z","timestamp":1421107200000},"content-version":"vor","delay-in-days":43,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:p>We describe the epilepsy features and emotion recognition abilities (recognition of basic facial emotions and recognition of emotional prosody) in a patient with Urbach\u2010Wiethe disease with bilateral amygdala calcifications. Our data, supported by ictal video\u2010EEG recording, indicated that our patient suffered from mesial temporal lobe epilepsy. Emotion recognition abilities were compared to those of healthy controls and those of patients with bilateral mesial temporal lobe epilepsy. Our patient showed a selective impairment of the recognition of facial expression of fear, whereas recognition of emotional prosody was preserved, in contrast to bilateral mesial temporal lobe epilepsy patients that presented with deficits in both domains. We also reviewed the literature on epilepsy in Urbach\u2010Wiethe disease (41 patients). Our findings suggest that in Urbach\u2010Wiethe disease, the circumscribed damage of both amygdalae results in a selective dysfunction of fearful face processing, in contrast to bilateral mesial temporal lobe epilepsy patients who present with a widespread and multimodal impairment in the judgement of emotional stimuli.<\/jats:p>","DOI":"10.1684\/epd.2014.0696","type":"journal-article","created":{"date-parts":[[2019,8,2]],"date-time":"2019-08-02T13:24:29Z","timestamp":1564752269000},"page":"518-527","source":"Crossref","is-referenced-by-count":34,"title":["Temporal lobe epilepsy and emotion recognition without amygdala: a case study of Urbach\u2010Wiethe disease and review of the literature"],"prefix":"10.1002","volume":"16","author":[{"given":"Stefano","family":"Meletti","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences, Metabolism, and Neurosciences; University of Modena and Reggio Emilia, Modena"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano","family":"Cantalupo","sequence":"additional","affiliation":[{"name":"Department of Life and Reproduction Sciences, University of Verona, Verona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Santoro","sequence":"additional","affiliation":[{"name":"IRCCS Institute of Neurological Sciences, Neurology Unit, Bellaria Hospital, Bologna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Benuzzi","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Metabolism, and Neurosciences; University of Modena and Reggio Emilia, Modena"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Federica","family":"Marliani","sequence":"additional","affiliation":[{"name":"IRCCS Institute of Neurological Sciences, Neuroradiology Unit, Bellaria Hospital, Bologna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo Alberto","family":"Tassinari","sequence":"additional","affiliation":[{"name":"Department of Neuroscience University of Parma  Parma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido","family":"Rubboli","sequence":"additional","affiliation":[{"name":"IRCCS Institute of Neurological Sciences, Neurology Unit, Bellaria Hospital, Bologna"},{"name":"Danish Epilepsy Centre Filadelfia\/University of Copenhagen  Dianalund Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/372669a0"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1037\/0894-4105.15.3.396"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2006.00018.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-008-0971-9"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2007.03115.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2011.11.024"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2011.01.027"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2007.02.014"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5251.557"},{"key":"e_1_2_8_11_1","first-page":"344","article-title":"Clinical and molecular abnormalities in lipoid proteinosis","volume":"15","author":"Desmet S.","year":"2005","journal-title":"Eur J Dermatol"},{"key":"e_1_2_8_12_1","first-page":"54","article-title":"Contribution to the recognition of Urbach\u2010Wiethe lipoid proteinosis (Hyalinosis cutis et mucosae)","volume":"10","author":"Eberhartinger C.","year":"1959","journal-title":"Hautarzt"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3323"},{"key":"e_1_2_8_14_1","first-page":"734","article-title":"Radiographic and computed tomographic findings in lipid proteinosis. 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