{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T15:29:59Z","timestamp":1780414199378,"version":"3.54.1"},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,1,25]],"date-time":"2016-01-25T00:00:00Z","timestamp":1453680000000},"content-version":"vor","delay-in-days":55,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Aim<\/jats:italic>. We describe two patients with refractory myoclonic status epilepticus treated with the ketogenic diet.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>. Between May 1, 2014 and January 1, 2015, two patients who met the diagnostic criteria for refractory myoclonic status epilepticus, seen at our department, were placed on the ketogenic diet and followed for a minimum of six months.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>. One patient with myoclonic epilepsy of unknown aetiology had a 75\u201390% seizure reduction, and the other with progressive encephalopathy associated with myoclonic epilepsy had a 50% seizure reduction. Both patients retained good tolerability for the diet. At the last control, one patient had isolated myoclonias and EEG showed occasional generalized spike\u2010and\u2010polyspike waves; the patient is now successfully attending kindergarten. The quality of life of the second patient improved significantly. In both cases, the number of antiepileptic drugs was reduced.<\/jats:p><jats:p><jats:italic>Conclusion<\/jats:italic>. The ketogenic diet is an effective and well\u2010tolerated treatment option for patients with refractory myoclonic status epilepticus and should be considered earlier in the course of treatment.<\/jats:p>","DOI":"10.1684\/epd.2015.0781","type":"journal-article","created":{"date-parts":[[2019,8,2]],"date-time":"2019-08-02T13:24:29Z","timestamp":1564752269000},"page":"491-495","source":"Crossref","is-referenced-by-count":23,"title":["The ketogenic diet in two paediatric patients with refractory myoclonic status epilepticus"],"prefix":"10.1002","volume":"17","author":[{"given":"Roberto Horacio","family":"Caraballo","sequence":"first","affiliation":[{"name":"Servicio de Neurolog\u00eda, Hospital de Pediatr\u00eda \u201cProf Dr Juan P Garrahan\u201d Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela Reyes","family":"Valenzuela","sequence":"additional","affiliation":[{"name":"Servicio de Neurolog\u00eda, Hospital de Pediatr\u00eda \u201cProf Dr Juan P Garrahan\u201d Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa","family":"Armeno","sequence":"additional","affiliation":[{"name":"Servicio de Neurolog\u00eda, Hospital de Pediatr\u00eda \u201cProf Dr Juan P Garrahan\u201d Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Fortini","sequence":"additional","affiliation":[{"name":"Servicio de Neurolog\u00eda, Hospital de Pediatr\u00eda \u201cProf Dr Juan P Garrahan\u201d Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graciela","family":"Mestre","sequence":"additional","affiliation":[{"name":"Servicio de Neurolog\u00eda, Hospital de Pediatr\u00eda \u201cProf Dr Juan P Garrahan\u201d Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Araceli","family":"Cresta","sequence":"additional","affiliation":[{"name":"Servicio de Neurolog\u00eda, Hospital de Pediatr\u00eda \u201cProf Dr Juan P Garrahan\u201d Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,25]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"783","volume-title":"Handbook of Clinical Neurology","author":"Caraballo R","year":"2013"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2011.06.009"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2014.09.033"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-011-9546-3"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073813487601"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2008.01765.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073809347597"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2011.03289.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2013.07.020"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2015.03.017"},{"key":"e_1_2_7_12_1","volume-title":"Status epilepticus, its clinical features and treatments in children and adults","author":"Shorvon S.","year":"2006"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2013.03.007"}],"container-title":["Epileptic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1684\/epd.2015.0781","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T16:25:32Z","timestamp":1710779132000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1684\/epd.2015.0781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["10.1684\/epd.2015.0781"],"URL":"https:\/\/doi.org\/10.1684\/epd.2015.0781","archive":["Portico"],"relation":{},"ISSN":["1294-9361","1950-6945"],"issn-type":[{"value":"1294-9361","type":"print"},{"value":"1950-6945","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12]]}}}