{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T14:14:02Z","timestamp":1785248042072,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T00:00:00Z","timestamp":1566518400000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>We report the first patient to die from refractory convulsive status epilepticus (SE) after the removal of a stimulator. The removal occurred after a two\u2010year period of successful control of super\u2010refractory convulsive SE with deep brain stimulation of the bilateral anterior nucleus of the thalamus (ANT\u2010DBS). The female patient, born in 1990, suffered from high fever and seizures, and was diagnosed with viral encephalitis in 2005. After four weeks of medical treatment, she recovered with no neurological disabilities, but suffered from monthly seizures. Ten years later, the patient presented with convulsive SE, while four months pregnant in February of 2015. Her SE remained super\u2010refractory to drugs despite the termination of pregnancy. Therefore, ANT\u2010DBS was performed in March of 2015. The patient became SE\u2010free following activation of an ANT\u2010DBS stimulator. However, the stimulation treatment was terminated according to the family's request when a tremor developed two years after the treatment had begun. Subsequently, four SE episodes occurred and the tremor did not improve. The stimulator and electrodes were removed in August of 2017. The patient died of an uncontrolled SE two months later. This case demonstrates the effectiveness of ANT\u2010DBS for emergency super\u2010refractory convulsive SE with both positive and negative outcomes.<\/jats:p>","DOI":"10.1684\/epd.2019.1086","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T16:28:15Z","timestamp":1706027295000},"page":"379-384","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Deep brain stimulation of the anterior nucleus of the thalamus in a patient with super\u2010refractory convulsive status epilepticus"],"prefix":"10.1002","volume":"21","author":[{"given":"Liu","family":"Yuan","sequence":"first","affiliation":[{"name":"Neurosurgery Department, Fourth Medical Center PLA General Hospital Beijing"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaohui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Neurosurgery Department, Fourth Medical Center PLA General Hospital Beijing"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuangshuang","family":"Liang","sequence":"additional","affiliation":[{"name":"Neurosurgery Department, Fourth Medical Center PLA General Hospital Beijing"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Liu","sequence":"additional","affiliation":[{"name":"Neurosurgery Department, Fourth Medical Center PLA General Hospital Beijing"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoman","family":"Yu","sequence":"additional","affiliation":[{"name":"Neurosurgery Department, Fourth Medical Center PLA General Hospital Beijing"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuli","family":"Liang","sequence":"additional","affiliation":[{"name":"Functional Neurosurgery Department, Beijing Children's Hospital Capital Medical University Beijing 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