{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,12]],"date-time":"2025-07-12T22:59:59Z","timestamp":1752361199103},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,1,17]],"date-time":"2020-01-17T00:00:00Z","timestamp":1579219200000},"content-version":"vor","delay-in-days":47,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Reflex seizures are consistently elicited by a specific afferent sensory stimulus or an activity undertaken by the patient. Among many known stimuli, defecation has rarely been reported. We describe the case of a child with reflex seizures triggered by defecation, considering the diagnostic challenge, epilepsy evaluation with video\u2010EEG monitoring, as well as impact on neuropsychology, behaviour and quality of life. The child was a 10\u2010year\u2010old boy with seizure onset at age four with epilepsy diagnosis established one and a half years later. Seizures were focal with impaired awareness triggered by defecation. Video\u2010EEG and structural and functional neuroimaging were performed and all pointed to the left temporal region. The patient became seizure\u2010free with carbamazepine and valproic acid. Neuropsychological and quality of life assessments suggested global impairment, both before and after seizure control. This is the third case of epilepsy induced by defecation reported in the literature. The rarity of this entity may be a diagnostic challenge and postpone specific treatment. Reporting of cases of defecation reflex epilepsy may provide a better understanding of its physiopathology and optimize effective treatment, avoiding cognitive, behavioural and poor social consequences. [\n            <jats:italic>Published with video sequence<\/jats:italic>\n            ]\n          <\/jats:p>","DOI":"10.1684\/epd.2019.1112","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T16:27:25Z","timestamp":1706027245000},"page":"579-584","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Defecation reflex seizures: a case report with long\u2010term VEEG monitoring, neuroimaging and comprehensive epilepsy evaluation"],"prefix":"10.1002","volume":"21","author":[{"given":"Renata Pina","family":"Rocha","sequence":"first","affiliation":[{"name":"Department of Neurosciences and Behavioural Sciences University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugenia Fialho","family":"Macedo","sequence":"additional","affiliation":[{"name":"Department of Neurosciences and Behavioural Sciences University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regina Maria Fran\u00e7a","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Department of Neurosciences and Behavioural Sciences University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula","family":"Thom\u00e9","sequence":"additional","affiliation":[{"name":"Department of Neurosciences and Behavioural Sciences University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Am\u00e9rico C.","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Neurosciences and Behavioural Sciences University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauro","family":"Wichert-Ana","sequence":"additional","affiliation":[{"name":"Section of Nuclear Medicine, Internal Medicine Department, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Paula Andrade","family":"Hamad","sequence":"additional","affiliation":[{"name":"Department of Neurosciences and Behavioural Sciences University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000115564"},{"key":"e_1_2_6_3_1","first-page":"1920","article-title":"Central processing of rectal pain: a functional MR imaging study","volume":"20","author":"Baciu M.V.","year":"1999","journal-title":"AJNR"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1684\/j.1950-6945.2001.tb00380.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5421"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.1.111"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.2001.22001.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2012.03709.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2005.66104.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.1966.tb06262.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2006.00859.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.2002.03202.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1684\/epd.2011.0423"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.2.302"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2005.17505.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1989.tb03846.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-282X2005000300004"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2007.01.010"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-693X(97)82616-4"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNP.0000000000000382"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0303-8467(84)90072-6"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S107669"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2006.09.002"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/78.4.445"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000312283.88683.0d"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.3345\/kjp.2008.51.12.1346"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-44462002000100006"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410320620"},{"key":"e_1_2_6_29_1","first-page":"35","article-title":"Seizure","volume":"2","author":"Striano S.","year":"1993","journal-title":"Epilepsia, arithmetices: study of four cases"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2009.12.010"}],"container-title":["Epileptic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1684\/epd.2019.1112","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T16:41:57Z","timestamp":1706028117000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1684\/epd.2019.1112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["10.1684\/epd.2019.1112"],"URL":"https:\/\/doi.org\/10.1684\/epd.2019.1112","archive":["Portico"],"relation":{},"ISSN":["1294-9361","1950-6945"],"issn-type":[{"value":"1294-9361","type":"print"},{"value":"1950-6945","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"2019-07-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}