{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T04:23:17Z","timestamp":1792815797988,"version":"4.5.0"},"reference-count":46,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,8,17]],"date-time":"2021-08-17T00:00:00Z","timestamp":1629158400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold><jats:italic>Objective<\/jats:italic><\/jats:bold>: Focal seizure semiology is often inadequately studied, specifically in preschool children. Among drug\u2010resistant epilepsies amenable to surgery, temporal lobe seizure semiology has been widely described in this age group. Nevertheless, a systematic anatomo\u2010electroclinical study has never been performed.<\/jats:p><jats:p><jats:bold><jats:italic>Methods<\/jats:italic><\/jats:bold>: We retrospectively reviewed the charts of patients younger than six years old at the time of video\u2010EEG recording who were operated on for temporal lobe epilepsy in our centre between 2010 and 2016. In order to describe the electroclinical semiology and establish anatomo\u2010clinical correlations, we reviewed all the recorded seizures on scalp and invasive video\u2010EEG and analysed pre\u2010 and postsurgical clinical data, MRI scans, and surgical and pathological data. We classified patients into the following four anatomical groups: mesio\u2010temporal, temporal lateral, polar, and mesio\u2010lateral, and for each group we selected video\u2010EEG samples for educational purposes.<\/jats:p><jats:p><jats:bold><jats:italic>Results<\/jats:italic><\/jats:bold>: Twenty\u2010eight patients fulfilled the selection criteria. Twenty\u2010three patients (82%) were explored with invasive electrodes that consisted of foramen ovale electrodes in 11 (39%) and stereoelectroencephalography in 12 (43%). The majority of the 53% of patients with mesio\u2010temporal epilepsies had specific ictal semiology, as described in adults. The others had subtle seizures or seizures limited to apnoea. The other groups also had some features comparable to adults, although no child reported the classic auras of lateral epilepsies. In total, 11% had infantile spasms (IS); post\u2010ictal examination provided lateralization signs in 28%. With a mean post\u2010surgical follow\u2010up duration of 5.5 years, 89% of the patients were classified as Engel Class I.<\/jats:p><jats:p><jats:bold><jats:italic>Significance<\/jats:italic><\/jats:bold>: Preschool children were shown to have non\u2010specific seizures, notably subtle events or IS. However, careful video\u2010EEG analysis can provide arguments for localizing the epileptogenic zone within the temporal lobe in most cases. Seizures with apnoea are characteristic of mesial temporal onset in patients with long\u2010term epilepsy\u2010associated tumours.<\/jats:p>","DOI":"10.1684\/epd.2021.1302","type":"journal-article","created":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T13:02:14Z","timestamp":1627563734000},"page":"590-610","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical semiology of temporal lobe seizures in preschool children: contribution of invasive recording to anatomical classification"],"prefix":"10.1002","volume":"23","author":[{"given":"Martine","family":"Fohlen","sequence":"first","affiliation":[{"name":"Pediatric neurosurgery Department Rothschild Fondation hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Taussig","sequence":"additional","affiliation":[{"name":"Pediatric neurosurgery Department Rothschild Fondation hospital Paris 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