{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:29:11Z","timestamp":1760956151235},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T00:00:00Z","timestamp":1644883200000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The role of neuroinflammation in epileptogenesis is extensively investigated, but short\u2010term effects of seizures on established CNS pathologies are less studied and less predictable. We describe the case of a woman with previous recurrent episodes of focal cerebral haemorrhage of unknown cause who developed a pseudo\u2010tumoural oedema triggered by provoked focal status epilepticus. A brain biopsy revealed that the underlying condition was primary angiitis of the CNS. Ictal\u2010induced blood\u2010brain barrier dysfunction allows the entry of water and inflammatory molecules that, in the context of CNS inflammatory diseases, may trigger a self\u2010reinforcing process. Caution should be observed when tapering antiepileptic drugs in patients with such conditions.<\/jats:p>","DOI":"10.1684\/epd.2021.1381","type":"journal-article","created":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T11:53:42Z","timestamp":1643975622000},"page":"203-207","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Focal status epilepticus may trigger relapse of primary angiitis of the CNS"],"prefix":"10.1002","volume":"24","author":[{"given":"Antoine","family":"Guilmot","sequence":"first","affiliation":[{"name":"Saint\u2010Luc University Hospital, Department of Neurology  Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia Maldonado","family":"Slootjes","sequence":"additional","affiliation":[{"name":"Saint\u2010Luc University Hospital, Department of Neurology  Brussels 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