{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:02:41Z","timestamp":1790737361016,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T00:00:00Z","timestamp":1654560000000},"content-version":"vor","delay-in-days":67,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case study of a surgical candidate, a 51\u2010year\u2010old woman with left temporal lobe epilepsy, who failed a left injection intracarotid amobarbital procedure (<jats:italic>e.g<\/jats:italic>., Wada test), scoring 0 of 8 items. This raised concerns for postoperative memory decline. However, the patient was uninterested in a neuromodulatory approach and wished to be reconsidered for surgery. A stereotactic laser amygdalohippocampotomy (SLAH) was considered, encouraging the need for an alternative test to evaluate risk of memory decline. We developed a novel approach to testing memory during stimulation of a depth electrode implanted in the hippocampus, <jats:italic>i.e<\/jats:italic>., an <jats:italic>electric Wada<\/jats:italic>. During multiple stimulation trials across a range of amplitudes, the patient scored up to 8 of 8 items, which suggested strong contralateral memory support. The surgical team proceeded with a radiofrequency ablation and a subsequent SLAH. The patient remains seizure\u2010free at 12 months post SLAH with no evidence of verbal or visuospatial memory decline based on a post\u2010surgical neuropsychological battery. We believe that this case study provides a proof of concept for the feasibility and possible utility of an electric version of the Wada procedure. Future studies are needed to develop an optimal paradigm and to validate this approach.<\/jats:p>","DOI":"10.1684\/epd.2021.1390","type":"journal-article","created":{"date-parts":[[2022,5,21]],"date-time":"2022-05-21T06:41:35Z","timestamp":1653115295000},"page":"411-416","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Electrical Wada for pre\u2010surgical memory testing: a case report"],"prefix":"10.1002","volume":"24","author":[{"given":"Erik","family":"Kaestner","sequence":"first","affiliation":[{"name":"Center for Multimodal Imaging and Genetics University of California San Diego CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel P.","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Department of Neurology Emory University School of Medicine Atlanta GA USA"},{"name":"Department of Biomedical Engineering Georgia Tech Atlanta GA 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of Neurology Emory University School of Medicine Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelsey C.","family":"Hewitt","sequence":"additional","affiliation":[{"name":"Department of Neurology Emory University School of Medicine Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Epstein","sequence":"additional","affiliation":[{"name":"Department of Neurology Emory University School of Medicine Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie R.","family":"McDonald","sequence":"additional","affiliation":[{"name":"Center for Multimodal Imaging and Genetics University of California San Diego CA USA"},{"name":"Department of Psychiatry University of California San Diego CA USA"},{"name":"San Diego State University\/University of California San Diego Joint Doctoral Program in Clinical Psychology San Diego CA 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