{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:52:46Z","timestamp":1777618366227,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T00:00:00Z","timestamp":1654560000000},"content-version":"vor","delay-in-days":67,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective<\/jats:italic> Febrile status epilepticus evolves from a febrile seizure (FS) in 5% of cases. Its prompt recognition is challenging, especially when motor manifestations are absent or subtle. We describe the ictal electroclinical features of non\u2010convulsive febrile status epilepticus (NCFSE) following an apparently concluded FS, initially misinterpreted as postictal obtundation and in some way mimicking the described \u201cnon\u2010epileptic twilight state\u201d.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic> We present an electroclinical study of 18 children, collected in our unit, who presented with NCFSE after an apparently resolved FS, longitudinally followed for one year to seven years and nine months (mean: four years and three months). The age at first NCFSE ranged between one year and two months and five years and eight months (mean: two years and six months). Patients were examined after spontaneous or rectal diazepam\u2010induced resolution of a FS, while showing persisting impairment of awareness.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic> A lack of responsiveness to painful stimulation, abnormal posturing and aphasia were present in all cases, variably associated with perioral cyanosis, hypersalivation, automatisms, gaze deviation and other lateralizing signs; eyes were open. The EEG recording started 20 to 140 minutes after the apparent resolution of the FS and was invariably characterized by delta or theta\u2010delta pseudorhythmic activity, mainly involving the fronto\u2010temporal regions, with hemispheric predominance in two thirds of the cases. The electroclinical condition, lasting 25 to 210 minutes, quickly recovered after intravenous diazepam. Follow\u2010up revealed normal neurodevelopment and EEG in almost all patients (learning disability emerged in three). In five subjects, NCSE relapsed (twice in two). None presented afebrile seizures.<\/jats:p><jats:p><jats:italic>Significance<\/jats:italic> Our series highlights the electroclinical features of focal NCFSE. Distinctive elements are a lack of reactivity, cyanosis, lateralizing clinical and EEG signs, and resolution clearly tied to intravenous benzodiazepine administration.<\/jats:p>","DOI":"10.1684\/epd.2021.1402","type":"journal-article","created":{"date-parts":[[2022,5,21]],"date-time":"2022-05-21T06:41:35Z","timestamp":1653115295000},"page":"387-396","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Non\u2010convulsive febrile status epilepticus mimicking a postictal state after a febrile seizure: an ictal electroclinical and evolutive study"],"prefix":"10.1002","volume":"24","author":[{"given":"Jacopo","family":"Proietti","sequence":"first","affiliation":[{"name":"U.O.C. di Neuropsichiatria Infantile, Dipartimento ad Attivit\u00e0 Integrata Materno Infantile \u2013 AOUI di Verona Verona Italy"},{"name":"PhD program Applied Sciences of Life and Health University of Verona Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Fiorini","sequence":"additional","affiliation":[{"name":"U.O.C. di Neuropsichiatria Infantile, Dipartimento ad Attivit\u00e0 Integrata Materno Infantile \u2013 AOUI di Verona Verona Italy"},{"name":"Centro Ricerca per le Epilessie in et\u00e0 Pediatrica (CREP) Azienda Ospedaliera Universitaria di Verona Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Meneghello","sequence":"additional","affiliation":[{"name":"U.O.C. di Neuropsichiatria Infantile, Dipartimento ad Attivit\u00e0 Integrata Materno Infantile \u2013 AOUI di Verona Verona Italy"},{"name":"U.O.S. di Neuropsichiatria Infantile Azienda Ulss9 Scaligera Verona (Italy)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaetano","family":"Cantalupo","sequence":"additional","affiliation":[{"name":"U.O.C. di Neuropsichiatria Infantile, Dipartimento ad Attivit\u00e0 Integrata Materno 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