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A group of experts was brought together by the International League Against Epilepsy (ILAE) to formulate recommendations for such circumstances. Every effort was made to base these recommendations on direct published literature or extrapolations from basic information available about ASMs. Actual published literature in this area is, however, limited, and at times, assumptions were made by the experts to generate these recommendations. During times of shortage of ASMs, switching between different ASMs (<jats:italic>e.g.<\/jats:italic>, oxcarbazepine and carbamazepine) can occasionally be considered as a mitigation procedure. However, for many ASMs, the option of an overnight switch to another drug does not exist. Switching from brand to generic or between generic products has often been shown to be safe, if required. Finally, when supplies of benzodiazepines or equipment to administer medications intravenously are not available, rectal administration of some ASMs may be an emergency alternative route for treating serial seizures and status epilepticus. Decision\u2010making with regard to treatment and possible options should be driven by what is best for the patient.<\/jats:p>","DOI":"10.1684\/epd.2022.1468","type":"journal-article","created":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T13:27:16Z","timestamp":1658928436000},"page":"751-764","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Recommendations for treatment strategies in people with epilepsy during times of shortage of antiseizure medications"],"prefix":"10.1002","volume":"24","author":[{"given":"Ali A.","family":"Asadi\u2010Pooya","sequence":"first","affiliation":[{"name":"Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Neurology, Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archana A.","family":"Patel","sequence":"additional","affiliation":[{"name":"Boston Children\u2019s Hospital, Harvard Medical School. Department of Neurology, Division of Epilepsy &amp; Clinical Neurophysiology  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugen","family":"Trinka","sequence":"additional","affiliation":[{"name":"Department of Neurology, Christian\u2010Doppler Medical Centre Paracelsus Medical University, Centre for Cognitive Neuroscience Salzburg, Member of the European Reference Network, EpiCARE, Salzburg, Austria; Department of Public Health, Health Services Research and Health Technology Assessment, UMIT \u2013 University for Health Sciences, Medical Informatics and Technology, Hall in Tirol, Austria; Karl\u2010Landsteiner Institute for Neurorehabilitation and Space Neurology, Salzburg, Austria; Neuroscience Institute..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Mazurkiewicz\u2010Beldzinska","sequence":"additional","affiliation":[{"name":"Department of Developmental Neurology Chair of Neurology, Medical University of Gda\u0144sk  Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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