{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:14:25Z","timestamp":1788480865503,"version":"build-2803163510"},"reference-count":0,"publisher":"Il Pensiero Scientifico Editore","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,1,1]]},"abstract":"<jats:p>SUMMARY. Background. A number of studies suggest that the clinical characteristics and long-term outcome of schizoaffective patients closely resemble those observed in schizophrenia when cases are diagnosed according to DSM criteria. The primary aim was to compare remission and recovery rates in a cohort of chronic schizoaffective and schizophrenic outpatients. Methods. A sample of 102 consecutive outpatients, 46 affected by schizophrenia (45.1%, mean age 44.22\u00b19.97 years) and 66 affected by schizoaffective disorder (54.9%, mean age 43.00\u00b19.07 years) was examined in the study. Personal data and psychiatric history were collected according to AMDP system; premorbid assessment was performed by means of PAS. Axis I and II psychiatric diagnosis was confirmed by means of SCID-I and II. Psychopathological status was evaluated by means of PANSS and CGI-SCH scales; neuropsychological evaluation was performed by means of BACS and MMSE; Functioning, subjective well-being and quality of life were respectively evaluated by means of PSP, SWN and WHOQoL-bref. Results. Schizophrenic and schizoaffective patients investigated were characterized by an overlapping age at onset, mean duration of illness, mean duration of untreated psychosis and common sociodemographic characteristics; subjects\u2019 cross-sectional psychopathological and neurocognitive profiles were remarkably similar. However, schizoaffective patients are more frequently of the female gender, showing a better social premorbid adjustment and a somewhat more complicated clinical course in terms of more frequent hospitalizations and suicidality; outcome measures are substantially better among schizoaffective patients: rates of clinical remission were 43.5% and 54.5% in schizophrenic and schizoaffective patients, respectively; 13% and 25.8% of schizophrenic and schizoaffective patients, respectively, were considered as functionally remitted; recovery was observed in 6.5% and 22.7% of schizophrenic and schizoaffective patients, respectively; the majority of patients, both schizophrenic and schizoaffective, were taking antipsychotics, mainly atypical, although a significantly higher proportion of schizoaffective subjects were on mood stabilizers, antidepressants and benzodiazepines. Conclusion. Compared to schizophrenic patients, DSM-IV-TR schizoaffective patients may be considered as a subgroup of psychotic patients displaying several specific characteristics in terms of clinical course, clinical and functional outcome and treatment.<\/jats:p>","DOI":"10.1708\/1407.15624","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T19:52:57Z","timestamp":1769457177000},"source":"Crossref","is-referenced-by-count":5,"title":["Long-term outcome of schizoaffective disorder. Are there any differences with respect to schizophrenia?"],"prefix":"10.1708","volume":"49","author":[{"given":"Federica","family":"Pinna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Sanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Perra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachele","family":"Pisu Randaccio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrica","family":"Diana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernardo","family":"Carpiniello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"The Cagliari Recovery Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"55112","container-title":["Rivista di Psichiatria"],"original-title":[],"deposited":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T19:52:57Z","timestamp":1769457177000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.rivistadipsichiatria.it\/articoli.php?archivio=yes&vol_id=1407&id=15624"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1,1]]}},"URL":"https:\/\/doi.org\/10.1708\/1407.15624","relation":{"is-cited-by":[{"id-type":"doi","id":"10.3389\/fpsyt.2017.00045","asserted-by":"object"},{"id-type":"doi","id":"10.21203\/rs.3.rs-8503226\/v1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/0020764019882709","asserted-by":"object"}]},"ISSN":["0035-6484"],"issn-type":[{"value":"0035-6484","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1,1]]}}}