{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:01:01Z","timestamp":1785456061704,"version":"3.56.0"},"reference-count":0,"publisher":"Il Pensiero Scientifico Editore","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,3,1]]},"abstract":"<jats:p>SUMMARY. Aim. A wide range of clinical phenomena have been reported with dose reduction or drug discontinuation of Selective Serotonin Reuptake Inhibitors (SSRIs) or Serotonin Norepinephrine Reuptake Inhibitors (SNRIs). In 2015, a new classification of SSRIs\/SNRIs withdrawal (i.e., new withdrawal symptoms, rebound symptoms withdrawal, persistent post-withdrawal disorders) was outlined on the basis of the literature and clinical observations. A semistructured clinical interview, the Diagnostic clinical Interview for Drug Withdrawal 1 - New Symptoms of SSRI and SNRI (DID-W1), was developed for identifying and differentiating such syndromes. Its inter-rater reliability has been tested. Methods. Seventeen consecutive outpatients with a history of SSRI or SNRI dose reduction or discontinuation were assessed independently by 2 clinicians at different times during the same day. Percent agreement, Cohen\u2019s kappa, and the squared correlation coefficient were used to measure inter-rater reliability. Results. The percent agreement for the whole interview was 97.06%, the Cohen\u2019s kappa 0.85 (95% CI of 0.61-1.08), the squared correlation coefficient 0.72. Discussion and conclusions. The kappa values indicated excellent inter-rater agreement. Validity evaluation and comparison with other instruments need to be performed. The DID-W1 may help diagnosing the clinical phenomena related to SSRI and SNRI discontinuation, their differentiation from relapse, and the potential iatrogenic origin of psychiatric symptoms in clinical practice.<\/jats:p>","DOI":"10.1708\/2891.29158","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T20:47:27Z","timestamp":1769460447000},"source":"Crossref","is-referenced-by-count":1,"title":["The Diagnostic clinical Interview for Drug Withdrawal 1 (DID-W1) \u2013 New Symptoms of Selective Serotonin Reuptake Inhibitors (SSRI) or Serotonin Norepinephrine Reuptake Inhibitors (SNRI): inter-rater reliability"],"prefix":"10.1708","volume":"53","author":[{"given":"Fiammetta","family":"Cosci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guy","family":"Chouinard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie-Anne","family":"Chouinard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni Andrea","family":"Fava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"55112","container-title":["Rivista di Psichiatria"],"original-title":[],"deposited":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T20:47:28Z","timestamp":1769460448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.rivistadipsichiatria.it\/articoli.php?archivio=yes&vol_id=2891&id=29158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,3,1]]}},"URL":"https:\/\/doi.org\/10.1708\/2891.29158","relation":{"is-cited-by":[{"id-type":"doi","id":"10.32872\/cpe.v1i2.32158","asserted-by":"object"},{"id-type":"doi","id":"10.1159\/000540031","asserted-by":"object"},{"id-type":"doi","id":"10.3389\/fpsyt.2020.574357","asserted-by":"object"}]},"ISSN":["0035-6484"],"issn-type":[{"value":"0035-6484","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3,1]]}}}