{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T12:33:02Z","timestamp":1787401982088,"version":"build-2736575974"},"reference-count":26,"publisher":"The Korean Society of Anesthesiologists","issue":"4","license":[{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004071","name":"Khon Kaen University","doi-asserted-by":"publisher","award":["63240"],"award-info":[{"award-number":["63240"]}],"id":[{"id":"10.13039\/501100004071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["anesth-pain-med.org"],"crossmark-restriction":true},"short-container-title":["Anesth Pain Med"],"published-print":{"date-parts":[[2022,10,31]]},"abstract":"<jats:p>Background: Thoracic paravertebral block (PVB) is an effective regional block for pain control after breast surgery. However, accidentally puncturing adjacent vital structures may cause undesirable complications. Erector spinae plane block (ESPB) has been considered a safer proxy of PVB for beginners. This study aimed to evaluate the analgesic effects of ultrasound-guidance PVB and ESPB after breast surgery.Methods: This randomized control trial was conducted in patients who underwent mastectomy. Forty-four females were randomly allocated into PVB group or ESPB group. All patients received a block with 20 ml of 0.5% levobupivacaine before general anesthesia. The primary outcome was the 24-h postoperative morphine requirements. The other outcomes of interest were postoperative pain scores, time to first analgesic request, dermatome of sensory blockade, block-related complications, and opioid adverse events.Results: The 24-h morphine requirements were significantly lower in PVB compared to the ESPB group (3.5 \u00b1 3.3 vs. 8.6 \u00b1 3.8 mg, P &lt; 0.001). The overall pain scores were also lower in the PVB group (P &lt; 0.001). Only 14 patients in the PVB group requested additional morphine, whereas all patients in the ESPB group requested it (P = 0.004). The dermatome of sensory blockade was wider in the PVB group (7 vs. 4 levels, P = 0.019). No serious complications occurred in either group.Conclusions: Compared to ESPB, PVB provided lower postoperative opioid requirements, lower pain scores, and wider sensory blockade after mastectomy.<\/jats:p>","DOI":"10.17085\/apm.22157","type":"journal-article","created":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T02:21:11Z","timestamp":1663640471000},"page":"445-453","update-policy":"https:\/\/doi.org\/10.17085\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A randomized double-blind controlled study comparing erector spinae plane block and thoracic paravertebral block for postoperative analgesia after breast surgery"],"prefix":"10.17085","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7843-689X","authenticated-orcid":true,"given":"Aumjit","family":"Wittayapairoj","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3465-6772","authenticated-orcid":true,"given":"Nattanan","family":"Sinthuchao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7427-0896","authenticated-orcid":true,"given":"Ongart","family":"Somintara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6933-6846","authenticated-orcid":true,"given":"Viriya","family":"Thincheelong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1260-471X","authenticated-orcid":true,"given":"Wilawan","family":"Somdee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2573","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.7314\/apjcp.2016.17.s3.43"},{"key":"ref2","first-page":"170","volume-title":"Factors associated with acute postoperative pain following breast reconstruction. JPRAS Open 2017; 11: 1-13","author":"Kulkarni","year":"2021"},{"key":"ref3","first-page":"1973","volume-title":"Prevalence of and factors associated with persistent pain following breast cancer surgery. JAMA 2009; 302: 1985-92","author":"G\u00e4rtner","year":"2012"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3344\/kjp.2018.31.3.155"},{"key":"ref5","first-page":"48","volume-title":"Comparision of thoracic epidural block vs paravertebral block in patients under going breast surgery","author":"Soni","year":"2015"},{"key":"ref6","first-page":"2367","volume-title":"Erector spinae plane block and paravertebral block for breast surgery: a retrospective propensity-matched noninferiority trial","author":"Aoyama","year":"2020"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2018.06.033"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/ija.ija_758_18"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4103\/ija.ija_310_19"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2019.06.036"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.4103\/ija.ija_536_19"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2019-101013"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e3181af7e7b"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/s0007-1226(96)90218-0"},{"key":"ref15","first-page":"621","volume-title":"The erector spinae plane block: a novel analgesic technique in thoracic neuropathic pain","author":"Forero","year":"2016"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/aap.0000000000000789"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14408"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-020-01613-8"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2019-100893"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-020-01002-0"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097\/01.aoa.0000552928.96744.71"},{"key":"ref22","first-page":"212","volume-title":"In-plane ultrasound-guided thoracic paravertebral block: a preliminary report of 36 cases with radiologic confirmation of catheter position","author":"Renes","year":"2010"},{"key":"ref23","first-page":"575","volume-title":"Single-injection versus multiple-injection technique of ultrasound-guided paravertebral blocks: a randomized controlled study comparing dermatomal spread","author":"Uppal","year":"2017"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeq265"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/262070"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.5812\/kowsar.22287523.3443"}],"container-title":["Anesthesia and Pain Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/anesth-pain-med.org\/upload\/pdf\/apm-22157.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/anesth-pain-med.org\/journal\/view.php?doi=10.17085\/apm.22157","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/anesth-pain-med.org\/upload\/pdf\/apm-22157.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,30]],"date-time":"2022-10-30T22:07:27Z","timestamp":1667167647000},"score":1,"resource":{"primary":{"URL":"http:\/\/anesth-pain-med.org\/journal\/view.php?doi=10.17085\/apm.22157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,31]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,10]]}},"URL":"https:\/\/doi.org\/10.17085\/apm.22157","relation":{},"ISSN":["1975-5171","2383-7977"],"issn-type":[{"value":"1975-5171","type":"print"},{"value":"2383-7977","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,31]]},"assertion":[{"value":"2022-03-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-20","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-31","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}