{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T01:55:34Z","timestamp":1783734934652,"version":"3.55.0"},"reference-count":9,"publisher":"Media Sphere Publishing House","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["S.S. Korsakov J. Neuro. Psych."],"published-print":{"date-parts":[[2024,4,23]]},"abstract":"<jats:p>Objective. To study the quality of life (QoL) of patients with multiple sclerosis (MS) in the Smolensk region who receive MS disease-modifying therapies (DMT). Material and methods. The study included 37 patients receiving MS DMT. The 36-Item Short Form Health Survey (SF-36), the Multiple sclerosis Quality of Life (MusiQol), the Hamilton Depression Rating Scale, a scale of satisfaction with treatment, the Fatigue Severity Scale were administered. Results. The results of the survey showed a decrease in QoL of MS patients compared to the control group. The level of disability and the duration of the disease have the greatest impact on QoL. Factors such as sex, MS DMT, and the socio-economic status of the patient have less impact on QoL. Conclusion. Given the priority impact of the level of disability on QoL of the patient, there is a need for earlier prescription of DMT to stop the progression of the disease.<\/jats:p>","DOI":"10.17116\/jnevro202412412136","type":"journal-article","created":{"date-parts":[[2024,12,28]],"date-time":"2024-12-28T08:09:17Z","timestamp":1735373357000},"page":"36","source":"Crossref","is-referenced-by-count":1,"title":["Quality of life of patients with multiple sclerosis in the Smolensk region"],"prefix":"10.17116","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0183-5643","authenticated-orcid":false,"given":"N.N.","family":"Maslova","sequence":"first","affiliation":[{"name":"Smolensk State Medical University","place":["Smolensk, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2597-9887","authenticated-orcid":false,"given":"V.E.","family":"Nikitenkova","sequence":"additional","affiliation":[{"name":"Smolensk State Medical University","place":["Smolensk, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8821-5804","authenticated-orcid":false,"given":"U.E.","family":"Gapeeva","sequence":"additional","affiliation":[{"name":"Smolensk State Medical University","place":["Smolensk, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4732-2287","authenticated-orcid":false,"given":"P.A.","family":"Shchukin","sequence":"additional","affiliation":[{"name":"Smolensk State Medical University","place":["Smolensk, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6743","reference":[{"key":"key-10.17116\/jnevro202412412136-1","doi-asserted-by":"publisher","DOI":"10.14412\/2074-2711-2022-1S-9-15"},{"key":"key-10.17116\/jnevro202412412136-2","doi-asserted-by":"publisher","DOI":"10.17116\/jnevro20191192242"},{"key":"key-10.17116\/jnevro202412412136-3","doi-asserted-by":"publisher","DOI":"10.20538\/1682-0363-2008-5-1-236-238"},{"key":"key-10.17116\/jnevro202412412136-4","unstructured":"https:\/\/www.mediasphera.ru\/issues\/zhurnal-nevrologii-i-psikhiatrii-im-s-s-korsakova-2\/2015\/8\/downloads\/ru\/271997-729820150853 Maslova NN, Pysina AM, Epischeva JuV. Et al. Neuropsychological aspects and quality of life of patients with multiple sclerosis. Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova. 2015;115(8-2):67-67. (In Russ.). Available from: @@https:\/\/www.mediasphera.ru\/issues\/zhurnal-nevrologii-i-psikhiatrii-im-s-s-korsakova-2\/2015\/8\/downloads\/ru\/271997-729820150853"},{"key":"key-10.17116\/jnevro202412412136-5","doi-asserted-by":"publisher","DOI":"10.5455\/medarh.2020.74.368-373"},{"key":"key-10.17116\/jnevro202412412136-6","unstructured":"https:\/\/scienceeducation.ru\/ru\/article\/view?id=7160"},{"key":"key-10.17116\/jnevro202412412136-7","unstructured":"Balyazin VA, Goncharova ZA, Rudenko OYu. The factors which influence the multiply sclerosis patients\u2019 quality of life. Sovremennyye problemy nauki i obrazovaniya. 2012;(5):56. 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