{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T11:53:22Z","timestamp":1782820402088,"version":"3.54.5"},"reference-count":33,"publisher":"Practical Medicine Publishing House","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prob. Balneo. Physio. Exer. Therapy"],"published-print":{"date-parts":[[2024,4,22]]},"abstract":"<jats:p>Several chronic non-communicable diseases are associated with arterial hypertension and are closely related to increased blood pressure. The theory of centralized aerobic-anaerobic energy balance compensation (TCAAEBC) was formulated in connection with the above-mentioned processes. This theory, including the hypothesis of the \u00abegoistic brain\u00bb, is a broader concept. The key point of TCAAEBC is hypoxic anaerobic metabolism, which affects reflex vascular zones, including the neurons of the respiratory and cardiovascular centers of the rhomboid fossa of the medulla oblongata. Hypoxia correction using manual techniques, physical exercises, and other non-pharmaceutical methods under certain conditions can stabilize the level of blood pressure and has a curative effect in the case of arterial hypertension syndrome.<\/jats:p>","DOI":"10.17116\/kurort202410102134","type":"journal-article","created":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T05:33:41Z","timestamp":1713504821000},"page":"34","source":"Crossref","is-referenced-by-count":1,"title":["Theory of centralized aerobic-anaerobic energy balance compensation and non-pharmaceutical treatment methods of arterial hypertension"],"prefix":"10.21320","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0251-2715","authenticated-orcid":false,"given":"A.Yu.","family":"Shishonin","sequence":"first","affiliation":[{"name":"Dr. Shishonin\u2019s Clinic","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.V.","family":"Yakovleva","sequence":"additional","affiliation":[{"name":"Dr. Shishonin\u2019s Clinic","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8926-5627","authenticated-orcid":false,"given":"K.V.","family":"Zhukov","sequence":"additional","affiliation":[{"name":"Dr. Shishonin\u2019s Clinic","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4828-8571","authenticated-orcid":false,"given":"A.A.","family":"Vecher","sequence":"additional","affiliation":[{"name":"Dr. Shishonin\u2019s Clinic","place":["Moscow, Russia"]},{"name":"Peoples\u2019 Friendship University of Russia","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4294-239X","authenticated-orcid":false,"given":"B.A.","family":"Gasparyan","sequence":"additional","affiliation":[{"name":"Dr. Shishonin\u2019s Clinic","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5131-7401","authenticated-orcid":false,"given":"V.I.","family":"Pavlov","sequence":"additional","affiliation":[{"name":"S.I. Spasokukotsky Moscow Scientific and Practical Center for Medical Rehabilitation, Restorative and Sports Medicine","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"8834","reference":[{"key":"key-10.17116\/kurort202410102134-1","unstructured":"Yunusova SG, Rozental\u2019 AN, Baltina TV. Stress. Biologicheskij i psihologicheskij aspekty. Uchenye zapiski Kazanskogo gosudarstvennogo universiteta. Gumanitarnye nauki. 2008;150(3):139-150. (In Russ.)"},{"key":"key-10.17116\/kurort202410102134-2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00057.2021"},{"key":"key-10.17116\/kurort202410102134-3","doi-asserted-by":"publisher","DOI":"10.31744\/einstein_journal\/2019AO4685"},{"key":"key-10.17116\/kurort202410102134-4","unstructured":"Krotkova IF, Ebzeeva EYu. Simptomaticheskie arterial\u2019nye gipertenzii. Spravochnik poliklinicheskogo vracha. 2017;3:21-25. (In Russ.)"},{"key":"key-10.17116\/kurort202410102134-5","doi-asserted-by":"publisher","DOI":"10.15829\/1560-4071-2020-3-3786"},{"key":"key-10.17116\/kurort202410102134-6","unstructured":"Shulepova AM, Tanatarova GN. Snizhenie effektivnosti antigipertenzivnoj terapii arterial\u2019noj gipertenzii I stepeni pri vertebrogennoj patologii. Nauka i zdravoohranenie. 2014;6:68-72. (In Russ.)"},{"key":"key-10.17116\/kurort202410102134-7","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2022.110835"},{"key":"key-10.17116\/kurort202410102134-8","doi-asserted-by":"crossref","unstructured":"Fehm HL, Kern W, Peters A.The selfish brain: competition for energy resources. Progress in Brain Research. Elsevier. 2006;153:129-140","DOI":"10.1016\/S0079-6123(06)53007-9"},{"key":"key-10.17116\/kurort202410102134-9","doi-asserted-by":"publisher","DOI":"10.3390\/life14010157"},{"key":"key-10.17116\/kurort202410102134-10","unstructured":"Vetcher AA, Zhukov KV, Gasparuan BA, Shishonin AY. The Role of Cervical Vertebral Arteries Blood Flow in Centralized Aerobic- Anaerobic Energy Balance Compensation: When Hypothesis Becomes a Theory. Ann Cardiovasc Dis. 2021;5(1):1027-1032"},{"key":"key-10.17116\/kurort202410102134-11","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61752-3"},{"key":"key-10.17116\/kurort202410102134-12","doi-asserted-by":"crossref","unstructured":"De Simone G, Mancusi C, Esposito R, De Luca N, Galderisi M. Echocardiography in Arterial Hypertension. High Blood Press Cardiovasc Prev. 2018;25(2):159-166","DOI":"10.1007\/s40292-018-0259-y"},{"key":"key-10.17116\/kurort202410102134-13","doi-asserted-by":"crossref","unstructured":"Finocchi C, Sassos D. Headache and arterial hypertension. Neurol Sci. 2017;38(S1):67-72","DOI":"10.1007\/s10072-017-2893-x"},{"key":"key-10.17116\/kurort202410102134-14","doi-asserted-by":"crossref","unstructured":"Wermelt JA, Schunkert H. Management of arterial hypertension. Herz. 2017;42(5):515-526","DOI":"10.1007\/s00059-017-4574-1"},{"key":"key-10.17116\/kurort202410102134-15","unstructured":"Ivanova ES, Karpova AV. Osteohondroz, kak odin iz faktorov riska razvitiya arterial\u2019noj gipertonii. Profilakticheskaya medicina. 2020;5(2):17-18. (In Russ.)"},{"key":"key-10.17116\/kurort202410102134-16","unstructured":"Osteohondroz pozvonochnika. Klinicheskie rekomendacii. M. 2016. Accessed March 16, 2024. (In Russ.). https:\/\/img-cdn.tinkoffjournal.ru\/osteohondroz-pozvonochnika.pdf"},{"key":"key-10.17116\/kurort202410102134-17","doi-asserted-by":"crossref","unstructured":"Rapsomaniki E, Timmis A, George J, Pujades-Rodriguez M, Shah AD, Denaxas S, White IR, Caulfield MJ, Deanfield JE, Smeeth L, Williams B, Hingorani A, Hemingway H. Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1\u00b725 million people. Lancet. 2014;383(9932):1899-1911","DOI":"10.1016\/S0140-6736(14)60685-1"},{"key":"key-10.17116\/kurort202410102134-18","unstructured":"Chertkov AK, Kutepov SM, Muhochev VA. Lechenie osteohondroza poyasnichnogo otdela pozvonochnika protezirovaniem mezhpozvonkovyh diskov funkcional\u2019nymi endoprotezami. Travmatologiya i Ortopediya Rossii. 2000;3:58-62. (In Russ.)"},{"key":"key-10.17116\/kurort202410102134-19","unstructured":"Dittmar C. Ein neuer Beweis fiir die Reizbarkeit der centripetalen Fasern des Riickenmarks. Ber. Verhandl. siiclis. Gesellsch. Wissensch. (Math.-Phys. K.). 1870;22:18"},{"key":"key-10.17116\/kurort202410102134-20","unstructured":"Dittmar C. Uber die Lage des sogenanntcn Gefasszentrums in der Medulla oblongata. Ber u Verh Ges Math.-physik. 1873;25:449-469"},{"key":"key-10.17116\/kurort202410102134-21","unstructured":"Owsjannikov PH. Die tonischen und reflectorischen Centren des Gefassnerven. Ber. Verhandl. sachs. Gesellsch. Wissenseh. (Math.-Phys. K.). 1871;23:135"},{"key":"key-10.17116\/kurort202410102134-22","doi-asserted-by":"crossref","unstructured":"Wang SC, Ranson SW. Autonomic responses to electrical stimulation of the lower brain stem. Journal of Comparative Neurology. 1939;71(3):437-455","DOI":"10.1002\/cne.900710304"},{"key":"key-10.17116\/kurort202410102134-23","doi-asserted-by":"crossref","unstructured":"Wang SC, Ranson SW. Descending pathways from the hypothalamus to the medulla and spinal cord. Observations on blood pressure and bladder responses. Journal of Comparative Neurology. 1939;71(3):457-472","DOI":"10.1002\/cne.900710305"},{"key":"key-10.17116\/kurort202410102134-24","doi-asserted-by":"crossref","unstructured":"Alexander RS. Tonic and reflex functions of medullary sympathetic cardiovascular centers. Journal of Neurophysiology. 1946;9(3):205-217","DOI":"10.1152\/jn.1946.9.3.205"},{"key":"key-10.17116\/kurort202410102134-25","unstructured":"Mihajlova SD, Semushkina TN, Sokolov AV, Mikaelyan NP, Storozhakov GI. Impul\u2019snaya aktivnost\u2019 bul\u2019barnyh kardiovaskulyarnyh nejronov pri gipoksii i giperkapnii. Vestnik RGMU. 2012;4;55-61. (In Russ.)"},{"key":"key-10.17116\/kurort202410102134-26","unstructured":"Drapkina OM, Vasil\u2019eva LE. Vliyanie sindroma obstruktivnogo sonnogo apnoe na serdechno-sosudistyj risk u pacientov s ozhireniem. Profilakticheskaya medicina. 2020;5(2):21-22. (In Russ.)"},{"key":"key-10.17116\/kurort202410102134-27","unstructured":"Dushenko K. Net nichego praktichnee horoshej teorii. Himiya i zhizn\u2019. Elektronnyj zhurnal. 2024Accessed March 16, 2024. (In Russ.). https:\/\/hij.ru\/read\/26641\/"},{"key":"key-10.17116\/kurort202410102134-28","unstructured":"Ermoshkin VI. Gipoteza o besprichinnoj gipertonii. \u00abZdorov\u2019e i obrazovanie v XXI veke\u00bb (Seriya medicina). 2012;14:53-59. (In Russ.)"},{"key":"key-10.17116\/kurort202410102134-29","doi-asserted-by":"crossref","unstructured":"He ZB, Lv Y-K, Li H, Yao Q, Wang K, Song X, Wu Z, Qin X. Atlantoaxial Misalignment Causes High Blood Pressure in Rats: A Novel AHT Model. BioMed Res Int. 2017;2017:5986957","DOI":"10.1155\/2017\/5986957"},{"key":"key-10.17116\/kurort202410102134-30","doi-asserted-by":"publisher","DOI":"10.3390\/ECB2023-14551"},{"key":"key-10.17116\/kurort202410102134-31","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11082147"},{"key":"key-10.17116\/kurort202410102134-32","doi-asserted-by":"publisher","DOI":"10.29328\/journal.abb.1001031"},{"key":"key-10.17116\/kurort202410102134-33","doi-asserted-by":"publisher","DOI":"10.3390\/polym13234248"}],"container-title":["Problems of Balneology, Physiotherapy and Exercise Therapy"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T11:31:27Z","timestamp":1782819087000},"score":1,"resource":{"primary":{"URL":"https:\/\/mediasphera.ru\/issues\/voprosy-kurortologii-fizioterapii-i-lechebnoj-fizicheskoj-kultury\/2024\/2\/1004287872024021034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,22]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,4,19]]}},"alternative-id":["10.17116\/kurort202410102134"],"URL":"https:\/\/doi.org\/10.17116\/kurort202410102134","relation":{},"ISSN":["0042-8787"],"issn-type":[{"value":"0042-8787","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4,22]]}}}