{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:22:51Z","timestamp":1747200171458,"version":"3.40.5"},"reference-count":28,"publisher":"Media Sphere Publishing House","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Burdenko's Journal of Neurosurgery"],"published-print":{"date-parts":[[2023,12,6]]},"abstract":"<jats:p>Background. Management of patients in acute period of aneurysmal subarachnoid hemorrhage Hunt\u2014Hess grade IV-V is still a complex and unsolved problem, especially regarding surgical treatment and various complications. Objective. To analyze postoperative outcomes in patients undergoing surgery in acute period of aneurysmal subarachnoid hemorrhage Hunt\u2014Hess grade IV\u2014V between 2006 and 2020, as well as to assess various factors influencing treatment outcomes. Material and methods. We analyzed 163 patients who underwent surgery within 21 days after aneurysmal subarachnoid hemorrhage Hunt\u2014Hess grade IV\u2014V. All patients were divided into 2 groups depending on the period: 2006\u20142011 (group 1) and 2012\u20142020 (group 2). Results. Mortality reduced from 28.6% in group 1 to 8.3% in group 2. At the same time, incidence of vegetative state (GOS grade 2) increased from 4.8% to 17.4%. Incidence of outcomes GOS grade 3 \u2014 5 was similar. Conclusion. Large or giant aneurysm, repeated preoperative subarachnoid hemorrhage, intraoperative aneurysm rupture and prolonged temporary clipping can impair postoperative outcomes in patients with hemorrhage Hunt\u2014Hess grade IV\u2014V. External ventricular drainage, intraarterial injection of verapamil, intracisternal administration of calcium channel blockers and active surgical tactics improve postoperative outcomes and reduce mortality.<\/jats:p>","DOI":"10.17116\/neiro2023870615","type":"journal-article","created":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T09:14:21Z","timestamp":1701854061000},"page":"5","source":"Crossref","is-referenced-by-count":0,"title":["Surgical treatment of intracranial aneurysms in acute period of hemorrhage in Hunt\u2014Hess grade IV\u2014V patients at Burdenko Neurosurgical Center between 2006 and 2020"],"prefix":"10.17116","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6103-9329","authenticated-orcid":false,"given":"Sh.Sh.","family":"Eliava","sequence":"first","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4001-3212","authenticated-orcid":false,"given":"Yu.V.","family":"Pilipenko","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4908-8923","authenticated-orcid":false,"given":"O.B.","family":"Belousova","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4734-3815","authenticated-orcid":false,"given":"G.I.","family":"Gvazava","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2622-7804","authenticated-orcid":false,"given":"F.V.","family":"Grebenev","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0932-4752","authenticated-orcid":false,"given":"An.N.","family":"Konovalov","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4721-9320","authenticated-orcid":false,"given":"K.G.","family":"Mikeladze","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8870-7649","authenticated-orcid":false,"given":"M.D.","family":"Varyukhina","sequence":"additional","affiliation":[{"name":"Federal Research Clinical Center of Intensive Care and Rehabilitology","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6743","reference":[{"key":"key-10.17116\/neiro2023870615-1","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyaa465"},{"key":"key-10.17116\/neiro2023870615-2","unstructured":"Belousova OB. 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