{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T02:09:12Z","timestamp":1794276552559,"version":"4.9.0"},"reference-count":19,"publisher":"Media Sphere Publishing House","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Burdenko's Journal of Neurosurgery"],"published-print":{"date-parts":[[2024,4,23]]},"abstract":"<jats:p>Robot-assisted implantation of deep electrodes for stereo-EEG monitoring has become popular in recent years in patients with drug-resistant epilepsy. However, there are still few data on safety of this technique. Objective. To assess the incidence of complications in patients with drug-resistant epilepsy undergoing robot-assisted implantation of stereo-EEG electrodes. Material and methods. We retrospectively studied the results of implantation of stereo-EEG electrodes in 187 patients with drug-resistant epilepsy. All patients underwent non-invasive preoperative examination (video-EEG, MRI, PET, SPECT, MEG). In case of insufficient data, stereo-EEG monitoring was prescribed. We determined electrode insertion trajectory using a robotic station and MR images. Implantation of electrodes was carried out using a Rosa robot (Medtech, France). All patients underwent invasive EEG monitoring after implantation. Results. There were 11.25\u00b13 electrodes per a patient. Implantation of one electrode took 7.5\u00b14.9 min. Postoperative MRI revealed electrode malposition in 2.3% of cases. None was associated with complications. The complication rate per electrode was 0.6%. Complications affected stereo-EEG monitoring only in 3 cases (1.6%). The mortality rate was 0.5%. Bilateral implantation (p=0.005), insular (p=0.040) and occipital (p=0.045) deep electrode implantation were associated with lower incidence of complications. Longer duration of the procedure influenced the incidence of electrode placement in the lateral ventricle (p=0.028), and implantation in the frontal lobe was more often associated with epidural placement of electrodes (p=0.039). Conclusion. Robot-assisted implantation of stereo-EEG electrodes is a safe procedure with minimal risk of complications. Rare electrode malposition does not usually affect invasive monitoring.<\/jats:p>","DOI":"10.17116\/neiro20248801128","type":"journal-article","created":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T15:50:11Z","timestamp":1707493811000},"page":"28","source":"Crossref","is-referenced-by-count":2,"title":["Safety of robot-assisted implantation of deep electrodes for invasive stereo-EEG monitoring"],"prefix":"10.17116","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8107-3065","authenticated-orcid":false,"given":"I.M.","family":"Alekseev","sequence":"first","affiliation":[{"name":"Pirogov National Medical Surgical Center","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2379-2836","authenticated-orcid":false,"given":"Zh.Zh.","family":"Pekov","sequence":"additional","affiliation":[{"name":"Pirogov National Medical Surgical Center","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2713-5904","authenticated-orcid":false,"given":"N.V.","family":"Pedyash","sequence":"additional","affiliation":[{"name":"Pirogov National Medical Surgical Center","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2974-1462","authenticated-orcid":false,"given":"A.A.","family":"Zuev","sequence":"additional","affiliation":[{"name":"Pirogov National Medical Surgical Center","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6743","reference":[{"key":"key-10.17116\/neiro20248801128-1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.14596"},{"key":"key-10.17116\/neiro20248801128-2","doi-asserted-by":"publisher","DOI":"10.1111\/epi.13492"},{"key":"key-10.17116\/neiro20248801128-3","doi-asserted-by":"crossref","unstructured":"Rosenow F, Luders H. Presurgical evaluation of epilepsy. Brain. 2001;124(Pt 9):1683-1700","DOI":"10.1093\/brain\/124.9.1683"},{"key":"key-10.17116\/neiro20248801128-4","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2019.0098"},{"key":"key-10.17116\/neiro20248801128-5","doi-asserted-by":"publisher","DOI":"10.1016\/j.nec.2015.08.003"},{"key":"key-10.17116\/neiro20248801128-6","doi-asserted-by":"publisher","DOI":"10.17116\/neiro20218502199"},{"key":"key-10.17116\/neiro20248801128-7","doi-asserted-by":"publisher","DOI":"10.1007\/s11548-016-1452-x"},{"key":"key-10.17116\/neiro20248801128-8","doi-asserted-by":"crossref","unstructured":"Sutherland GR, Maddahi Y, Gan LS, Lama S, Zareinia K. Robotics in the neurosurgical treatment of glioma. 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