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Each aneurysm was assessed regarding contrast enhancement pattern. Microsurgical treatment of aneurysm was accompanied by resection of its wall for subsequent histological and immunohistochemical analysis regarding thrombosis, inflammation and neovascularization. Specimens were subjected to histological and immunochemical analysis. Immunohistochemical analysis was valuable to estimate inflammatory markers CD68 and CD3, as well as neurovascularization marker SD31. Results. Aneurysms with contrast-enhanced walls were characterized by higher number of CD3+, CD68+, CD31+ cells and parietal clots. Intensity of contrast enhancement correlated with aneurysm wall abnormalities. Conclusion. Contrast enhancement of aneurysm wall can characterize various morphological abnormalities.<\/jats:p>","DOI":"10.17116\/neiro20248803152","type":"journal-article","created":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T04:27:33Z","timestamp":1718598453000},"page":"52","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of intracranial saccular aneurysm wall: neuroimaging and histopathological correlates"],"prefix":"10.17116","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1897-9312","authenticated-orcid":false,"given":"K.S.","family":"Semin","sequence":"first","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8447-2600","authenticated-orcid":false,"given":"G.A.","family":"Demyashkin","sequence":"additional","affiliation":[{"name":"Sechenov First Moscow State Medical University","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0516-3613","authenticated-orcid":false,"given":"N.E.","family":"Zakharova","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6103-9329","authenticated-orcid":false,"given":"Sh.Sh.","family":"Eliava","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6395-2055","authenticated-orcid":false,"given":"A.S.","family":"Kheireddin","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0932-4752","authenticated-orcid":false,"given":"A.N.","family":"Konovalov","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8719-2225","authenticated-orcid":false,"given":"D.B.","family":"Kalaeva","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8924-7346","authenticated-orcid":false,"given":"A.I.","family":"Batalov","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4480-0275","authenticated-orcid":false,"given":"I.N.","family":"Pronin","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgical Center","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6743","reference":[{"key":"key-10.17116\/neiro20248803152-1","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyy310"},{"key":"key-10.17116\/neiro20248803152-2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2019.0006"},{"key":"key-10.17116\/neiro20248803152-3","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.017391"},{"key":"key-10.17116\/neiro20248803152-4","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20180950"},{"key":"key-10.17116\/neiro20248803152-5","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurad.2018.09.007"},{"key":"key-10.17116\/neiro20248803152-6","doi-asserted-by":"publisher","DOI":"10.17116\/neiro20238705155"},{"key":"key-10.17116\/neiro20248803152-7","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000140636.30204.da"},{"key":"key-10.17116\/neiro20248803152-8","doi-asserted-by":"crossref","unstructured":"Roa JA, Zanaty M, Osorno-Cruz C, Ishii D, Bathla G, Ortega-Gutierrez S, Hasan DM, Samaniego EA. 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