{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:40:57Z","timestamp":1759412457992,"version":"3.40.5"},"reference-count":21,"publisher":"Media Sphere Publishing House","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rus. Ann. Ophthal."],"published-print":{"date-parts":[[2023,3,16]]},"abstract":"<jats:p>Purpose. The study evaluates the effectiveness of eyelid hygiene (EH) in correction of the ocular surface (OS) condition in patients with dry eye disease (DED) ahead of cataract phacoemulsification (CPE). Material and methods. The study included 90 patients with cataract: the first group consisted of 45 DED patients with lipid deficiency, the second group \u2014 45 DED patients with lipid\/mucous deficiency. Prior to CPE, all patients were randomized into three subgroups of 15 people each. In subgroups 1.1 and 2.1 patients did not receive any treatment for correction of the state of ocular surface. Patients in subgroups 1.2 and 1.3 were instilled 0.18% sodium hyaluronate (SH); in subgroups 2.2 and 2.3 \u2014 fixed combination of 0.15% SH and 3% trehalose. In subgroups 1.3 and 2.3 EH was performed (with \u00abBlefarogel cleansing\u00bb, \u00abBlefarolotion\u00bb, \u00abBlefarogel-1\u00bb two times a day for one month before CPE). The control points were: 1) at study inclusion; 2) after correction of the ocular surface condition; 3) 30 days after CPE. The following parameters were evaluated: OSDI, TBUT (Norn\u2019s test), severity of meibomian gland dysfunction (MGD), patient satisfaction with CPE (CPE-PS). Statistical analysis: M\u00b1SD calculation, Mann-\u2014Whitney, Kruskal\u2014Wallis and Wilcoxon tests. Results. At the second control point, a statistically significant more pronounced OSDI decrease and bigger increase in TBUT were observed in subgroups 1.3 and 2.3 compared to subgroups 1.2 and 2.2 (Mann\u2014Whitney U-test). Apparently, this was associated with a reduction in MGD severity in patients who received EH. At the third control point, significant lower values of OSDI and MGD severity, higher TBUT values and greater CFE-PS were recorded in subgroups 1.3 and 2.3 (Kruskal\u2014Wallis test, Wilcoxon two-sample test). Conclusion. Carrying out EH using the \u00abBlefarogel cleansing\u00bb, \u00abBlefarolotion\u00bb, \u00abBlefarogel-1\u00bb and artificial tear in patients with DED and cataract can increase the efficiency of correction of ocular surface condition and improve patient satisfaction with the outcome of CPE.<\/jats:p>","DOI":"10.17116\/oftalma202313901146","type":"journal-article","created":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T18:20:49Z","timestamp":1678990849000},"page":"46","source":"Crossref","is-referenced-by-count":8,"title":["Therapeutic hygiene of eyelids in dry eye disease prior to cataract phacoemulsification"],"prefix":"10.17116","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2100-2972","authenticated-orcid":false,"given":"S.N.","family":"Sakhnov","sequence":"first","affiliation":[{"name":"Kuban State Medical University","place":["Krasnodar, Russia"]},{"name":"Krasnodar branch of S.N. Fedorov National Medical Research Center \u00abMNTK \u00abEye Microsurgery\u00bb","place":["Krasnodar, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7371-689X","authenticated-orcid":false,"given":"S.V.","family":"Yanchenko","sequence":"additional","affiliation":[{"name":"Kuban State Medical University","place":["Krasnodar, Russia"]},{"name":"Research Institute \u2014 Prof. S.V. Ochapovsky Regional Clinical Hospital No. 1","place":["Krasnodar, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1448-9690","authenticated-orcid":false,"given":"A.V.","family":"Malyshev","sequence":"additional","affiliation":[{"name":"Kuban State Medical University","place":["Krasnodar, Russia"]},{"name":"Research Institute \u2014 Prof. S.V. Ochapovsky Regional Clinical Hospital No. 1","place":["Krasnodar, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1511-1219","authenticated-orcid":false,"given":"G.Yu.","family":"Karapetov","sequence":"additional","affiliation":[{"name":"Research Institute \u2014 Prof. S.V. Ochapovsky Regional Clinical Hospital No. 1","place":["Krasnodar, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0243-0891","authenticated-orcid":false,"given":"T.G.","family":"Katkhanov","sequence":"additional","affiliation":[{"name":"Kuban State Medical University","place":["Krasnodar, Russia"]},{"name":"Research Institute \u2014 Prof. S.V. 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