{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:23:30Z","timestamp":1747200210612,"version":"3.40.5"},"reference-count":25,"publisher":"Media Sphere Publishing House","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rus. Ann. Ophthal."],"published-print":{"date-parts":[[2024,4,23]]},"abstract":"<jats:p>Purpose. This study evaluates the long-term results of surgical treatment of patients with Fuchs\u2019 endothelial corneal dystrophy and cataract. Material and methods. The study included 24 patients (24 eyes) with primary Fuchs\u2019 endothelial corneal dystrophy and cataract, who underwent cataract phacoemulsification with IOL implantation and of Descemet\u2019s membrane endothelial keratoplasty with a semicircular graft (hemi-DMEK). The effect of treatment was assessed by best corrected visual acuity (BCVA), central corneal thickness (CCT) and endothelial cell density (ECD). Results. In total, surgical treatment involved 14 donor corneas that were divided in half during the preparation and isolation of the Descemet\u2019s membrane (DM). By month 12 after the surgery an increase in visual functions and graft transparency were observed in 23 patients (23 eyes) out of 24. Repeated keratoplasty was required in one case due to fibrosis of the posterior layers of recipient\u2019s corneal stroma. At 12 months postoperatively, the study group showed an increase in BCVA from 0.16\u00b10.1 to 0.75\u00b120, a decrease in CCT from 650.9\u00b14.5 \u03bcm to 519.6\u00b143.9, and a decreased in ECD from 2850.5\u00b184.7 cells\/mm2 up to 1285.5\u00b1277.2 cells\/mm2. Thus, the loss of endothelial cells at one year after surgery amounted to 54.9%. Conclusions. The developed method for transplantation of a semicircular DM fragment provides a tissue-saving approach to endothelial keratoplasty, and considering the high percentage of transparent engraftment of grafts and complete visual rehabilitation, it can be recommended in the treatment of patients with cataract and Fuchs\u2019 endothelial corneal dystrophy.<\/jats:p>","DOI":"10.17116\/oftalma202414001136","type":"journal-article","created":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T10:05:28Z","timestamp":1709805928000},"page":"36","source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of hemi-Descemet membrane endothelial keratoplasty and phacoemulsification for the treatment of primary Fuchs\u2019 endothelial corneal dystrophy combined with cataract"],"prefix":"10.17116","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5666-3493","authenticated-orcid":false,"given":"B.E.","family":"Malyugin","sequence":"first","affiliation":[{"name":"S.N. 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