{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:26:46Z","timestamp":1783988806546,"version":"3.55.0"},"reference-count":14,"publisher":"Media Sphere Publishing House","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rus. Ann. Ophthal."],"published-print":{"date-parts":[[2024,4,23]]},"abstract":"<jats:p>Purpose. The study investigates corneal and higher-order internal aberrations in patients with amblyopia of different etiologies and their relationship with visual acuity, refraction, axial length, and fixation parameters. Material and methods. Forty-five patients (90 eyes) were examined. All patients were divided into five groups: 1 \u2014 with dysbinocular amblyopia; 2 \u2014 with refractive amblyopia; 3 \u2014 with anisometropic amblyopia; 4 \u2014 with relative amblyopia due to congenital myopia; 5 (control) \u2014 fellow eyes without amblyopia. Aberrometry was performed using the OPD-Scan III device (Nidek, Japan). Fixation parameters were studied on the MP-3 microperimeter (Nidek, Japan). Correlation analysis was performed using Pearson\u2019s linear correlation coefficient (r). Results. In amblyopia associated with congenital myopia, a significant increase in corneal and internal aberrations RMS, Total HOA, astigmatism (V) (0.65\u00b10.26; 1.01\u00b10.31; 4.22\u00b11.17; \u20132.17\u00b10.72; 0.86\u00b10.3, respectively; control group \u2014 0.44\u00b10.19; 0.58\u00b10.27; 1.0\u00b10.75; \u20130.94\u00b10.89; 0.47\u00b10.65) and internal spherical aberration (0.06\u00b10.02; control group \u2014 0.04\u00b10.03) was found. In dysbinocular amblyopia, a significant increase in internal aberrations Trefoil (V) and Coma (H) (0.75\u00b10.52 and 0.17\u00b10.35, respectively; control group \u2014 0.05\u00b10.28 and \u20130.07\u00b10.21) was found, which correlated with a decrease in fixation density in the 2\u00b0 ring (r= \u20130.40, r= \u20130.41). Conclusions. The increased level of higher-order aberrations in amblyopia associated with congenital myopia is due to the anatomical and optical features of the eyes. The increase in internal aberrations Trefoil (V) and Coma (H) in dysbinocular amblyopia is associated with a mismatch of the optical elements of the eye due to impaired fixation, i.e., it is not the cause, but the consequence of amblyopia.<\/jats:p>","DOI":"10.17116\/oftalma202414002148","type":"journal-article","created":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T09:57:10Z","timestamp":1715680630000},"page":"48","source":"Crossref","is-referenced-by-count":1,"title":["Wavefront characteristics in amblyopia of different etiologies in children"],"prefix":"10.17116","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8480-0894","authenticated-orcid":false,"given":"V.V.","family":"Neroev","sequence":"first","affiliation":[{"name":"Helmholtz National Medical Research Center of Eye Diseases","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8864-4518","authenticated-orcid":false,"given":"E.P.","family":"Tarutta","sequence":"additional","affiliation":[{"name":"Helmholtz National Medical Research Center of Eye Diseases","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8383-0127","authenticated-orcid":false,"given":"R.R.","family":"Khubieva","sequence":"additional","affiliation":[{"name":"Helmholtz National Medical Research Center of Eye Diseases","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6743","reference":[{"key":"key-10.17116\/oftalma202414002148-1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2019-314759"},{"key":"key-10.17116\/oftalma202414002148-2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.10.008"},{"key":"key-10.17116\/oftalma202414002148-3","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.12-9941"},{"key":"key-10.17116\/oftalma202414002148-4","doi-asserted-by":"publisher","DOI":"10.1016\/S1091-8531(03)00111-3"},{"key":"key-10.17116\/oftalma202414002148-5","doi-asserted-by":"crossref","unstructured":"Koshelev DI. 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