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Treatment of patients (171 patients, 182 eyes) with HRE included 2 consecutive stages: stage I \u2014 relief of acute symptoms of the disease with the help of conservative treatment (instillations of interferon inducers, autologous serum, corneal protectors, tear substitutes, use of therapeutic soft contact lenses); in some cases, phototherapeutic keratectomy was used in the absence of the effect of conservative therapy, as well as in the localization of the focus in the optical zone. Stage II involved anti-relapse therapy based on the use of a Russian-produced herpes vaccine in the intercurrent period. After vaccination, observation for 2 years or more showed that 81.3% of patients achieved clinical recovery (complete cessation of HRE recurrences), 15.8% had a decrease in the frequency and severity of relapses, while 2.9% of patients did not respond to the treatment.<\/jats:p>","DOI":"10.17116\/oftalma2024140022102","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T15:03:15Z","timestamp":1715612595000},"page":"102","source":"Crossref","is-referenced-by-count":0,"special_numbering":"Vyp. 2","title":["Recurrent herpetic erosion of the cornea: diagnosis, treatment and prevention of recurrences"],"prefix":"10.17116","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8594-2395","authenticated-orcid":false,"given":"Evg.A.","family":"Kasparova","sequence":"first","affiliation":[{"name":"Krasnov Research Institute of Eye Diseases","place":["Moscow, Russia"]},{"name":"OOO Moscow Research Ophthalmological Center \u201cNoviy Vzglyad\u201d","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3372-7989","authenticated-orcid":false,"given":"E.A.","family":"Kasparova","sequence":"additional","affiliation":[{"name":"OOO Moscow Research Ophthalmological Center \u201cNoviy Vzglyad\u201d","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6945-237X","authenticated-orcid":false,"given":"N.R.","family":"Marchenko","sequence":"additional","affiliation":[{"name":"Krasnov Research Institute of Eye Diseases","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.A.","family":"Kasparov","sequence":"additional","affiliation":[{"name":"Krasnov Research Institute of Eye Diseases","place":["Moscow, Russia"]},{"name":"OOO Moscow Research Ophthalmological Center \u201cNoviy Vzglyad\u201d","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6743","reference":[{"key":"key-10.17116\/oftalma2024140022102-1","unstructured":"Kurenkov VV. 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