{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:23:33Z","timestamp":1747200213099,"version":"3.40.5"},"reference-count":15,"publisher":"Media Sphere Publishing House","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rus. Ann. Ophthal."],"published-print":{"date-parts":[[2024,4,23]]},"abstract":"<jats:p>The influence of various patterns of preliminary femtosecond laser-assisted fragmentation of the lens nucleus on the energy and hydrodynamic parameters of phacoemulsification remains insufficiently studied. Purpose. This study evaluates the influence of various patterns of preliminary femtosecond laser-assisted fragmentation of the lens nucleus on the energy, hydrodynamic parameters of phacoemulsification, and the degree of corneal endothelial cell loss. Material and methods. Hybrid phacoemulsification was performed in 336 patients (336 eyes) with grade IV immature cataract according to the Buratto classification in three age-matched groups. Group 1 included 103 patients (103 eyes) who underwent hybrid phacoemulsification with preliminary femtosecond laser-assisted fragmentation of the nucleus with a \u00abpizza\u00bb pattern (division of the nucleus with 10 radial cuts). Group 2 included 112 patients (112 eyes) who underwent femtosecond laser-assisted fragmentation of the nucleus with a \u00abcylinders\u00bb pattern (division of the nucleus with 8 radial cuts in combination with 5 circular cuts). Group 3 included 121 patients (121 eyes) who underwent femtosecond laser-assisted fragmentation of the nucleus with a \u00abgrid\u00bb pattern (division of the nucleus with 8 radial cuts in combination with multiple mutually perpendicular cuts in the central zone in the form of a grid with a 0.5 mm cell). Effective ultrasound time and the volume of irrigation solution for emulsification of the lens nucleus fragments were determined during the operation. The loss of corneal endothelial cells was assessed 3 months after surgery. Results. The minimum effective ultrasound time was noted after using the \u201cgrid\u201d pattern \u2014 4.05 (2.88; 4.74) s, which was significantly less than with the \u201ccylinders\u201d pattern \u2014 4.97 (3.78; 5.88) s and the \u201cpizza\u201d pattern \u2014 6.15 (4.52; 7.75) s (p&lt;0.05). The effective ultrasound time when using the \u201ccylinders\u201d pattern was significantly less than with the \u201cpizza\u201d pattern (p&lt;0.05). The volume of irrigation solution used for emulsification of the lens nucleus fragments was significantly less in the \u201cgrid\u201d pattern \u2014 41.5 (33.5; 49.5) ml compared to the \u201ccylinders\u201d patterns 58.5 (51.0; 66.0), p&lt;0.05 and \u201cpizza\u201d pattern 75.0 (66.0; 83.5), p&lt;0.01. The volume of irrigation solution when using the \u201ccylinders\u201d pattern was significantly less than when using the \u201cpizza\u201d pattern (p&lt;0.05). The loss of corneal endothelial cells after using the \u201cgrid\u201d pattern was 8.82 (7.59; 9.87)%, which was significantly less than after the \u201ccylinders\u201d patterns \u2014 9.97 (8.81; 10.83)%, p&lt;0.05 and \u201cpizza\u201d \u2014 11.70 (10.62; 12.97)%, p&lt;0.05. At the same time, the loss of endothelial cells after using the \u201ccylinders\u201d pattern was significantly less than after the \u201cpizza\u201d pattern (p&lt;0.05). Conclusions. The choice of the optimal pattern of preliminary femtosecond laser-assisted fragmentation of the lens nucleus provides a significant decrease in the energy and hydrodynamic parameters of phacoemulsification and, accordingly, the loss of corneal endothelial cells.<\/jats:p>","DOI":"10.17116\/oftalma2024140022129","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T15:03:15Z","timestamp":1715612595000},"page":"129","source":"Crossref","is-referenced-by-count":0,"special_numbering":"Vyp. 2","title":["Influence of the pattern of femtosecond laser-assisted lens nucleus fragmentation on the energy and hydrodynamic parameters of phacoemulsification"],"prefix":"10.17116","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4043-456X","authenticated-orcid":false,"given":"Yu.N.","family":"Yusef","sequence":"first","affiliation":[{"name":"Krasnov Research Institute of Eye Disease","place":["Moscow, Russia"]},{"name":"I.M. Sechenov First Moscow State Medical University (Sechenov University)","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0486-7819","authenticated-orcid":false,"given":"S.N.","family":"Yusef","sequence":"additional","affiliation":[{"name":"Krasnov Research Institute of Eye Disease","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8134-8089","authenticated-orcid":false,"given":"A.S.","family":"Vvedenskiy","sequence":"additional","affiliation":[{"name":"Krasnov Research Institute of Eye Disease","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2001-9310","authenticated-orcid":false,"given":"M.N.","family":"Ivanov","sequence":"additional","affiliation":[{"name":"Krasnov Research Institute of Eye Disease","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6791-4219","authenticated-orcid":false,"given":"L.","family":"Alkharki","sequence":"additional","affiliation":[{"name":"Krasnov Research Institute of Eye Disease","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2450-0395","authenticated-orcid":false,"given":"N.D.","family":"Fokina","sequence":"additional","affiliation":[{"name":"I.M. Sechenov First Moscow State Medical University (Sechenov University)","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6743","reference":[{"key":"key-10.17116\/oftalma2024140022129-1","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20091117-04"},{"key":"key-10.17116\/oftalma2024140022129-2","unstructured":"Nagy Z. Femtosecond Laser-Assisted Cataract Surgery: Facts and Results. New-Jersey: SLACK Incorporated; 2014"},{"key":"key-10.17116\/oftalma2024140022129-3","unstructured":"Avetisov SE, Mamikonyan VR, Yusef YN, Yusef SN, Ivanov MN, Avetisov KS. Hybrid phacoemulsification: a new stage in the improvement of cataract surgery (?). Russian Annals of Ophthalmology=Vestnik oftal\u2019mologii. 2014;130(2):4-7. 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