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This review presents the results of morphological studies, including immunohistochemical studies, reflecting the features of biointegration of palpebral implants in uncomplicated and complicated course of the postoperative period, and describes the modern understanding of the causes and immunopathological processes underlying the development of nonspecific inflammatory response, which is one of the most serious complications that often becomes an indication for implant removal.<\/jats:p>","DOI":"10.17116\/oftalma2024140022166","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T15:03:15Z","timestamp":1715612595000},"page":"166","source":"Crossref","is-referenced-by-count":2,"special_numbering":"Vyp. 2","title":["Clinical and morphological aspects of the use of palpebral implants made of noble metals"],"prefix":"10.17116","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6461-8243","authenticated-orcid":false,"given":"Y.O.","family":"Grusha","sequence":"first","affiliation":[{"name":"Krasnov Research Institute of Eye Diseases","place":["Moscow, Russia"]},{"name":"I.M. 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