{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:23:38Z","timestamp":1747200218003,"version":"3.40.5"},"reference-count":19,"publisher":"Media Sphere Publishing House","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rus. Ann. Ophthal."],"published-print":{"date-parts":[[2024,4,23]]},"abstract":"<jats:p>Purpose. This study assesses the impact of preoperative administration of Oku-Oku eye drops on the severity of conjunctival hyperemia and the risk of hemorrhagic complications in the early postoperative period following glaucoma surgery. Material and methods. The study included a group of 30 patients (30 eyes) with uncontrolled primary open-angle glaucoma who underwent non-penetrating deep sclerectomy. The main group included 15 eyes, in which Oku-Oku drops were administered twice \u2014 on the day before surgery (upon hospital admission) and immediately before the operation. The control group consisted of 15 eyes that underwent surgery without additional medications. Intraocular pressure (IOP) and conjunctival hyperemia were measured before and after surgery. The duration of coagulation during surgery was also recorded. The rate of hemorrhagic complications was compared between the groups. Results. The performed glaucoma surgery significantly reduced IOP in both groups, with no significant differences in postoperative IOP levels. Conjunctival hyperemia increased in both groups postoperatively, though the increase was slightly less in the main group. There was a significant difference in the duration of scleral vessel coagulation in the surgical area, amounting to 3.8\u00b12.6 seconds in the main group and 6.9\u00b13.0 seconds in the control group. Hemorrhagic complications occurred less frequently in the main group. Conclusion. Preoperative use of Oku-Oku eye drops reduced the severity of conjunctival hyperemia and the width of scleral vessels. The reduction in hemorrhagic complications in the early postoperative period may contribute to decreased scarring. Oku-Oku can be included in the comprehensive preoperative preparation for glaucoma surgery and other procedures with a risk of bleeding. Further research is needed to evaluate the effectiveness of Oku-Oku in the perioperative period.<\/jats:p>","DOI":"10.17116\/oftalma2024140051118","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T12:30:43Z","timestamp":1732192243000},"page":"118","source":"Crossref","is-referenced-by-count":0,"title":["Perioperative prevention of bleeding in glaucoma surgery"],"prefix":"10.17116","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5171-8261","authenticated-orcid":false,"given":"A.A.","family":"Antonov","sequence":"first","affiliation":[{"name":"Krasnov Research Institute of Eye Diseases","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7735-9650","authenticated-orcid":false,"given":"A.A.","family":"Vitkov","sequence":"additional","affiliation":[{"name":"Krasnov Research Institute of Eye Diseases","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1421-8882","authenticated-orcid":false,"given":"A.V.","family":"Volzhanin","sequence":"additional","affiliation":[{"name":"Krasnov Research Institute of Eye Diseases","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3885-9649","authenticated-orcid":false,"given":"I.V.","family":"Kozlova","sequence":"additional","affiliation":[{"name":"Krasnov Research Institute of Eye Diseases","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4603-4873","authenticated-orcid":false,"given":"S.A.","family":"Ovsepyan","sequence":"additional","affiliation":[{"name":"Krasnov Research Institute of Eye Diseases","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6743","reference":[{"key":"key-10.17116\/oftalma2024140051118-1","doi-asserted-by":"publisher","DOI":"10.37690\/1811-0185-2020-10-26-36"},{"key":"key-10.17116\/oftalma2024140051118-2","doi-asserted-by":"publisher","DOI":"10.21516\/2072-0076-2024-17-1-7-19"},{"key":"key-10.17116\/oftalma2024140051118-3","doi-asserted-by":"publisher","DOI":"10.17116\/oftalma2016132396-102"},{"key":"key-10.17116\/oftalma2024140051118-4","doi-asserted-by":"publisher","DOI":"10.32364\/2311-7729-2020-20-3-133-141"},{"key":"key-10.17116\/oftalma2024140051118-5","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-015-0134-8"},{"key":"key-10.17116\/oftalma2024140051118-6","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1996.01100130258004"},{"key":"key-10.17116\/oftalma2024140051118-7","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2012.82"},{"key":"key-10.17116\/oftalma2024140051118-8","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007293.pub4"},{"key":"key-10.17116\/oftalma2024140051118-9","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(65)93017-5"},{"key":"key-10.17116\/oftalma2024140051118-10","doi-asserted-by":"crossref","unstructured":"Lama PJ, Fechtner RD. 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