{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:23:38Z","timestamp":1747200218879,"version":"3.40.5"},"reference-count":37,"publisher":"Media Sphere Publishing House","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rus. Ann. Ophthal."],"published-print":{"date-parts":[[2024,4,23]]},"abstract":"<jats:p>Purpose. This study aimed to identify factors associated with the development of myopic maculopathy (MM) in patients with acquired myopia. Material and methods. The study included a total of 135 patients (41 men, 94 women; 135 eyes) over 30 years old with acquired myopia and axial length (AL) of 26 mm. Forty-six patients had MM, while 89 (66%) had no macular changes. Optical coherence tomography angiography (OCT-A) and B-scan ultrasound of the eyes were performed to detect staphylomas of the posterior pole sclera. OCT was used to assess corneal stromal thickness and choroidal thickness. Corneal biomechanics were measured using the Corvis ST device, and ocular vessel hemodynamics were evaluated using color Doppler imaging. Binary logistic regression was employed, with a multivariable logistic model built for each of these potential risk factors, adjusted for sex, age, AL, and spherical equivalent (SE). Results. Age, AL, SE, and extra-macular myopic changes were significantly associated with the presence of MM. Of the seven qualitative risk factors studied, the presence of extra-macular changes, staphyloma, and wide macular staphyloma localization were statistically significant. Among the quantitative factors, significant associations were found with the width and depth of staphyloma, the area of the ultrasound cross-section of staphyloma (W\u00d7D), choroidal thickness in all examined zones, all corneal stromal thickness parameters, corneal deformation amplitude (DA), curvature radius highest concavity (radius HC), and corneal peak distance (PD). Conclusion. The statistically significant risk factors associated with MM were age, AL, SE, the presence and size of staphylomas, choroidal and corneal stromal thickness, as well as several parameters characterizing corneal biomechanical properties. The strongest associations with MM were found for corneal PD, staphyloma depth, and choroidal thickness in the nasal perifovea.<\/jats:p>","DOI":"10.17116\/oftalma202414005135","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T12:30:43Z","timestamp":1732192243000},"page":"35","source":"Crossref","is-referenced-by-count":0,"title":["Risk factors associated with myopic maculopathy in acquired myopia"],"prefix":"10.17116","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7501-5571","authenticated-orcid":false,"given":"O.V.","family":"Kolenko","sequence":"first","affiliation":[{"name":"Khabarovsk branch of the S.N. Fedorov National Medical Research Centre \u201cMNTK \u201cEye Microsurgery\u201d","place":["Khabarovsk, Russia"]},{"name":"Postgraduate Institute for Public Health Specialists","place":["Khabarovsk, Russia"]},{"name":"Far-Eastern State Medical University","place":["Khabarovsk, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9839-8429","authenticated-orcid":false,"given":"L.V.","family":"Bushnina","sequence":"additional","affiliation":[{"name":"Khabarovsk branch of the S.N. Fedorov National Medical Research Centre \u201cMNTK \u201cEye Microsurgery\u201d","place":["Khabarovsk, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5446-0633","authenticated-orcid":false,"given":"I.E.","family":"Pashentsev","sequence":"additional","affiliation":[{"name":"Khabarovsk branch of the S.N. Fedorov National Medical Research Centre \u201cMNTK \u201cEye Microsurgery\u201d","place":["Khabarovsk, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3757-8351","authenticated-orcid":false,"given":"N.V.","family":"Pomytkina","sequence":"additional","affiliation":[{"name":"Khabarovsk branch of the S.N. Fedorov National Medical Research Centre \u201cMNTK \u201cEye Microsurgery\u201d","place":["Khabarovsk, Russia"]},{"name":"Far-Eastern State Medical University","place":["Khabarovsk, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2028-1140","authenticated-orcid":false,"given":"E.L.","family":"Sorokin","sequence":"additional","affiliation":[{"name":"Khabarovsk branch of the S.N. Fedorov National Medical Research Centre \u201cMNTK \u201cEye Microsurgery\u201d","place":["Khabarovsk, Russia"]},{"name":"Far-Eastern State Medical University","place":["Khabarovsk, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6743","reference":[{"key":"key-10.17116\/oftalma202414005135-1","doi-asserted-by":"publisher","DOI":"10.17116\/oftalma2016132185-90"},{"key":"key-10.17116\/oftalma202414005135-2","unstructured":"Dalidovich AA. Diagnostics of myopic maculopathy. Ophthalmology. Eastern Europe. 2011;9(2):68-78 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-3","unstructured":"Budzinskaya MV, Zhabina OA, Andreeva IV, Plyukhova AA, Shchegoleva IV. Myopic maculopathy. In: X S\u201dezd oftal\u2019mologov Rossii [X Congress of Ophthalmologists of Russia]. M. 2015:142 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-4","unstructured":"Tarutta EP, Markosyan GA, Ryabinina MV, Zolnikova IV, Krouzhkova GV. Morphometric and functional features of macula in patients with high congenital myopia. Russian Annals of Ophthalmology = Vestnik oftal\u2019mologii. 2012;128(1):3-8 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-5","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.18-24032"},{"key":"key-10.17116\/oftalma202414005135-6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2019.07.010"},{"key":"key-10.17116\/oftalma202414005135-7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2016.01.005"},{"key":"key-10.17116\/oftalma202414005135-8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.04.022"},{"key":"key-10.17116\/oftalma202414005135-9","doi-asserted-by":"publisher","DOI":"10.3109\/09286580903450346"},{"key":"key-10.17116\/oftalma202414005135-10","doi-asserted-by":"publisher","DOI":"10.25276\/2410-1257-2018-2-95-97"},{"key":"key-10.17116\/oftalma202414005135-11","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2018.10.005"},{"key":"key-10.17116\/oftalma202414005135-12","unstructured":"Sorokin EL, Egorov VV, Kolenko OV, Zhirov AL, Bushnina LV. Study of the frequency and structure of degenerative myopia among patients with myopic refraction. Ophthalmology. 2013;10(1):14-17 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-13","unstructured":"Sorokin EL, Bushnina LV. Clarification of frequency of various myopic changes of ocular gundus in patients with complicated myopia and their part in the structure of patients with myopic refraction. Far Eastern Medical Journal. 2013;(3):89-91 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-14","unstructured":"Bushnina LV, Sorokin EL, Kashura OI, Pshenichnov MV. Issledovanie vozrastnogo perioda formirovaniya tsentral\u2019nykh oslozhnenii priobretennoi miopii. Modern Technologies in Ophthalmology. 2014;(2):97-99 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-15","unstructured":"Bushnina LV, Sorokin EL, Kolenko OV. The share of primary visual disability in patients with complicated myopia. Rossijskij obshchenatsional\u2019nyj oftal\u2019mologicheskij forum. 2013;1:197-198 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-16","unstructured":"Bushnina LV, Sorokin EL, Pashentsev YaE. Study of age-related features of morphometric indices of the macular zone in eyes with axial uncomplicated myopia. Modern Technologies in Ophthalmology. 2016;(4):38-42 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-17","unstructured":"Russian Federation patent for invention \u21162595001\/20.08.2016. Bull. \u211623. Sorokin EL, Bushnina LV. A method for predicting atrophic myopic maculopathy. (In Russ.). Accessed September 21, 2023. https:\/\/www1.fips.ru\/registers-doc-view\/fips_servlet?DB=RUPAT&DocNumber=2595001&TypeFile=html"},{"key":"key-10.17116\/oftalma202414005135-18","doi-asserted-by":"publisher","DOI":"10.25276\/0235-4160-2020-1-32-38"},{"key":"key-10.17116\/oftalma202414005135-19","doi-asserted-by":"publisher","DOI":"10.17116\/oftalma202213806155"},{"key":"key-10.17116\/oftalma202414005135-20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.01.020"},{"key":"key-10.17116\/oftalma202414005135-21","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2019-315255"},{"key":"key-10.17116\/oftalma202414005135-22","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.056727"},{"key":"key-10.17116\/oftalma202414005135-23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.01.035"},{"key":"key-10.17116\/oftalma202414005135-24","doi-asserted-by":"publisher","DOI":"10.17116\/oftalma2015131438-48"},{"key":"key-10.17116\/oftalma202414005135-25","unstructured":"Tarutta EP, Kushnarevich NYu. Biomechanical and hemodinamic factors to the genesis of chorioretinal dystrophies in myopia. Russian Annals of Ophthalmology = Vestnik oftal\u2019mologii. 1997;113(4):21-23 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-26","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-20742"},{"key":"key-10.17116\/oftalma202414005135-27","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.18-24471"},{"key":"key-10.17116\/oftalma202414005135-28","doi-asserted-by":"publisher","DOI":"10.1016\/j.oret.2019.04.023"},{"key":"key-10.17116\/oftalma202414005135-29","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-10660-z"},{"key":"key-10.17116\/oftalma202414005135-30","unstructured":"Iomdina EN. Biomechanical and biochemical disorders of the sclera in progressive myopia and methods of their correction. In: Visual functions and their correction in children. Avetisov SE, Kashchenko TP, Shamshinova AM, eds. M.: Meditsina; 2005:163-183 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-31","unstructured":"Curtin BJ. The posterior staphyloma of pathologic myopia. Trans Am Ophthalmol Soc. 1977;75:67-86"},{"key":"key-10.17116\/oftalma202414005135-32","unstructured":"Savitskaya NF, Nikolaeva TE. Comparative study of the structure of the vessels of the choroid and retina in emmetropia and myopia of varying degrees. Russian Annals of Ophthalmology = Vestnik oftal\u2019mologii. 1982;(3):44-47 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-33","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-12772"},{"key":"key-10.17116\/oftalma202414005135-34","unstructured":"Avetisov ES. Miopiya. M.: Meditsina; 1968 (In Russ.)"},{"key":"key-10.17116\/oftalma202414005135-35","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2017.10.005"},{"key":"key-10.17116\/oftalma202414005135-36","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.03.035"},{"key":"key-10.17116\/oftalma202414005135-37","doi-asserted-by":"publisher","DOI":"10.1002\/0471722146"}],"container-title":["Russian Annals of Ophthalmology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T08:40:53Z","timestamp":1745397653000},"score":1,"resource":{"primary":{"URL":"https:\/\/mediasphera.ru\/issues\/vestnik-oftalmologii\/2024\/5\/10042465X2024051035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,23]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,11,12]]}},"alternative-id":["10.17116\/oftalma202414005135"],"URL":"https:\/\/doi.org\/10.17116\/oftalma202414005135","relation":{},"ISSN":["0042-465X"],"issn-type":[{"type":"print","value":"0042-465X"}],"subject":[],"published":{"date-parts":[[2024,4,23]]}}}