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In four patients (16.7%), the inflammation was bilateral, while the remaining 20 (83.3%) had unilateral orbital involvement. A total of 13 US examinations were conducted in group 1, and 22 in group 2. All patients underwent orbital US, including duplex scanning of ocular and orbital vessels, along with multiplanar combined spatial analysis of the orbital inflammatory mass. Results. The ultrasound characteristics in orbital GPA, specifically acoustic density, presence of pathological blood flow within and around the inflammatory mass, and flow intensity varied according to the stage of the inflammatory process. Conclusion. Ultrasound is a non-invasive and accessible method for assessing inflammation activity in orbital GPA.<\/jats:p>","DOI":"10.17116\/oftalma202414006132","type":"journal-article","created":{"date-parts":[[2024,12,28]],"date-time":"2024-12-28T05:49:26Z","timestamp":1735364966000},"page":"32","source":"Crossref","is-referenced-by-count":0,"title":["Potential of ultrasonography in determination of orbital inflammation activity in granulomatosis with polyangiitis"],"prefix":"10.17116","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3460-9191","authenticated-orcid":false,"given":"D.S.","family":"Ismailova","sequence":"first","affiliation":[{"name":"Krasnov Research Institute of Eye Diseases","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0714-0730","authenticated-orcid":false,"given":"O.V.","family":"Eksarenko","sequence":"additional","affiliation":[{"name":"Krasnov Research Institute of Eye Diseases","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0148-5655","authenticated-orcid":false,"given":"P.I.","family":"Novikov","sequence":"additional","affiliation":[{"name":"I.M. Sechenov First Moscow State Medical University (Sechenov University)","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6743","reference":[{"key":"key-10.17116\/oftalma202414006132-1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-116-6-488"},{"key":"key-10.17116\/oftalma202414006132-2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2012.08.003"},{"key":"key-10.17116\/oftalma202414006132-3","unstructured":"Anderson G, Coles ET, Crane M, Douglas AC, Gibbs AR, Geddes DM, Peel ET, Wood JB Wegener\u2019s granuloma. A series of 265 British cases seen between 1975 and 1910. 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