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This review highlights the anatomy and vascularization of the LC, along with the latest research findings obtained via OCT. The article details age-related changes in the LC and the impact of intraocular pressure (IOP) changes on its properties. A novel parameter, the lamina cribrosa curvature index (LCCI), reflecting LC deformation, has been shown to be the most important biomarker of glaucomatous damage.<\/jats:p>","DOI":"10.17116\/oftalma202514101176","type":"journal-article","created":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T09:33:38Z","timestamp":1741253618000},"page":"76","source":"Crossref","is-referenced-by-count":2,"title":["The role of the structure of the lamina cribrosa in the diagnosis and treatment of glaucoma. Structural and circulatory changes in the lamina cribrosa with aging and elevated intraocular pressure"],"prefix":"10.17116","volume":"141","author":[{"given":"N.I.","family":"Kurysheva","sequence":"first","affiliation":[{"name":"Medical Biological University of Innovations and Continuing Education of the Federal Biophysical Center named after A.I. 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