{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T14:01:54Z","timestamp":1761746514986,"version":"build-2065373602"},"reference-count":10,"publisher":"Media Sphere Publishing House","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rus. Ann. Ophthal."],"published-print":{"date-parts":[[2025,10,29]]},"abstract":"<jats:p>Objective. This study aimed to analyze the dynamics of corneal wavefront aberration changes after local corneal cross-linking and assess their impact on visual acuity in patients with keratoconus. Material and methods. The study group included 22 patients (37 eyes) aged 17 to 36 years with stage I\u2014III keratoconus. All patients underwent local corneal cross-linking according to the Dresden protocol. The follow-up period was 12 months. In addition to standard ophthalmological examinations, specialized diagnostics were performed using the topographers-aberrometers Orbscan III, Sirius, and the optical coherence tomograph Revo. Higher-order aberrations were analyzed preoperatively and at 1, 6, and 12 months postoperatively. Corneal morphology parameters were also assessed at the same time points. Results. At 1 month postoperatively, there was a slight increase in higher-order aberrations compared to baseline. However, by the 6th month, higher-order aberrations began to decrease, reaching their lowest levels by month 12. The improvement in best-corrected visual acuity (BCVA) correlated with the reduction in higher-order aberrations: following a slight decline during the first month, BCVA began to improve by month 6 and peaked by the end of the follow-up period, increasing by 35% (t&gt;2.0; p&lt;0.05) compared with the preoperative level. Conclusion. Local cross-linking has a positive effect on higher-order aberrations. The reduction in higher-order aberrations correlates with improved visual acuity after local crosslinking.<\/jats:p>","DOI":"10.17116\/oftalma202514105172","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T11:08:33Z","timestamp":1761736113000},"page":"72","source":"Crossref","is-referenced-by-count":0,"title":["Wavefront changes after local cross-linking for keratoconus"],"prefix":"10.17116","volume":"141","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1922-4939","authenticated-orcid":false,"given":"S.I.","family":"Anisimov","sequence":"first","affiliation":[{"name":"Russian University of Medicine","place":["Moscow, Russia"]},{"name":"OOO Glaznoy Centr \u201cVostok-Prozrenie\u201d","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9396-306X","authenticated-orcid":false,"given":"S.M.","family":"Micovic","sequence":"additional","affiliation":[{"name":"Russian University of Medicine","place":["Moscow, Russia"]},{"name":"OOO Glaznoy Centr \u201cVostok-Prozrenie\u201d","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6105-1632","authenticated-orcid":false,"given":"N.S.","family":"Anisimova","sequence":"additional","affiliation":[{"name":"Russian University of Medicine","place":["Moscow, Russia"]},{"name":"OOO Glaznoy Centr \u201cVostok-Prozrenie\u201d","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.A.","family":"Gavrilova","sequence":"additional","affiliation":[{"name":"Russian University of Medicine","place":["Moscow, Russia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6743","reference":[{"key":"key-10.17116\/oftalma202514105172-1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2021.101559"},{"key":"key-10.17116\/oftalma202514105172-2","unstructured":"Egorova GB, Bobrovskikh NV, Zueva YuS. Optical aberrations of the eye and feasibilities of their compensation by means of contact lenses and surgical interventions in primary ametropias and keratoconus. The Russian Annals of Ophthalmology. 2007;123(5):47-51. (In Russ.)"},{"key":"key-10.17116\/oftalma202514105172-3","doi-asserted-by":"publisher","DOI":"10.1364\/JOSAA.27.000941"},{"key":"key-10.17116\/oftalma202514105172-4","doi-asserted-by":"publisher","DOI":"10.1016\/j.visres.2011.08.020"},{"key":"key-10.17116\/oftalma202514105172-5","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2016.06.005"},{"key":"key-10.17116\/oftalma202514105172-6","doi-asserted-by":"publisher","DOI":"10.4103\/2008-322X.176894"},{"key":"key-10.17116\/oftalma202514105172-7","unstructured":"Amsler M. La notion du k\u00e9ratoc\u00f4ne. Bulletin des soci\u00e9t\u00e9s d\u2018ophtalmologie de France. 1951;64:272-275. 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