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One of its major risk factors is computer vision syndrome, which leads to increased tear film evaporation due to reduced blink rate, an increased number of incomplete blinks, and the development of meibomian gland dysfunction (MGD). Other DED risk factors may include exogenous and systemic stimuli, as well as changes of the ocular surface, including MGD. This article presents an analysis of data on the epidemiology and clinical features of DED in young and middle-aged adults, as well as potential therapeutic strategies, including elimination of modifiable risk factors, differentiated tear replacement therapy, anti-inflammatory treatment, and eyelid hygiene, including the use of Blepharogel Ochischenie cleansing gel, Blepharolosion lotion, Blepharosalfetka wipes, Blepharogel 1, Blepharogel 2, and Blepharogel Forte.<\/jats:p>","DOI":"10.17116\/oftalma2026142011112","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T09:17:32Z","timestamp":1773825452000},"page":"112","source":"Crossref","is-referenced-by-count":1,"title":["Dry eye disease in young and middle-aged adults"],"prefix":"10.17116","volume":"142","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7371-689X","authenticated-orcid":false,"given":"S.V.","family":"Yanchenko","sequence":"first","affiliation":[{"name":"Bukhara State Medical Institute named after Abu Ali ibn Sino","place":["Bukhara, Uzbekistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3548-0581","authenticated-orcid":false,"given":"B.G.","family":"Hamroev","sequence":"additional","affiliation":[{"name":"Bukhara State Medical Institute named after Abu Ali ibn Sino","place":["Bukhara, Uzbekistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1448-9690","authenticated-orcid":false,"given":"A.V.","family":"Malyshev","sequence":"additional","affiliation":[{"name":"Maykop State Technological University","place":["Maykop, Adygea"]},{"name":"Scientific Research Institution \u2014 S.V. 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