{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T06:27:32Z","timestamp":1786516052141,"version":"build-2736575974"},"reference-count":15,"publisher":"Media Sphere Publishing House","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Stomatology"],"published-print":{"date-parts":[[2026,8,12]]},"abstract":"<jats:p>Objective. To carry out a comprehensive analysis of dental manifestations and identify the features of the dental system in children with premature aging syndromes. Material and methods. The study included 7 patients with premature aging syndromes: a boy and a girl with Hutchinson\u2014Gilford syndrome, 2 girls with Cockayne syndrome type A and B, one girl each with neonatal progeroid syndrome, Penttinen syndrome and mandibular hypoplasia, deafness, progeroid features and lipodystrophy (MDPL syndrome). During a clinical examination by a dentist, the condition of the hard tissues of the teeth, periodontal and oral mucosa was assessed. According to orthopantomography data, the condition of occlusion and dentition was assessed. Results. According to the results of the observations, a common pattern was revealed for all the examined patients: jaw hypoplasia and multiple caries. In patients with Hutchinson\u2014Guilford and MDPL-syndrome, crowding and multiple carious lesions of the teeth were the most characteristic; for a patient with Penttinen syndrome, mandibular macrognathia, mesial occlusion and thickening of the mucous membrane of the frontal, sphenoid sinuses, a decrease in the cells of the latticed labyrinth;a feature of neonatal progeroid syndrome is the presence of neonatal incisors at birth, followed by hypo-\/oligodontia or adentia. Conclusion. Knowledge of dento-mandibular anomalies in premature aging syndromes will allow dentists to timely detect pathologic changes in the dento-mandibular system and correct the dental status of patients with progeroid syndromes, which will significantly improve their quality of life.<\/jats:p>","DOI":"10.17116\/stomat202610504163","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T05:23:17Z","timestamp":1786512197000},"page":"63","source":"Crossref","is-referenced-by-count":0,"title":["Features of the dentoalveolar system in children with premature aging syndromes"],"prefix":"10.17116","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7363-3093","authenticated-orcid":false,"given":"A.L.","family":"Kungurtseva","sequence":"first","affiliation":[{"name":"I.M. Sechenov First Moscow State Medical University (Sechenov University)","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2209-0923","authenticated-orcid":false,"given":"Z.V.","family":"Sinkina","sequence":"additional","affiliation":[{"name":"LLC \u00abDocDent\u00bb","place":["Moscow, Russia"]},{"name":"LLC \u00abInwhite Medical\u00bb","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7747-6873","authenticated-orcid":false,"given":"Yu.V.","family":"Tikhonovich","sequence":"additional","affiliation":[{"name":"I.M. Sechenov First Moscow State Medical University (Sechenov University)","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0412-4938","authenticated-orcid":false,"given":"N.A.","family":"Sholokhova","sequence":"additional","affiliation":[{"name":"Children\u2019s state clinical hospital of St. Vladimir","place":["Moscow, Russia"]},{"name":"Russian Medical Academy of Continuous Professional Education","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5689-0194","authenticated-orcid":false,"given":"A.V.","family":"Vitebskaya","sequence":"additional","affiliation":[{"name":"I.M. Sechenov First Moscow State Medical University (Sechenov University)","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6743","reference":[{"key":"key-10.17116\/stomat202610504163-1","doi-asserted-by":"crossref","unstructured":"Golounina OO, Fadeev VV, Belaya ZE. Hereditary syndromes with signs of premature aging. Osteoporosis and osteopathies. 2019;22(3):4-18. (In Russ.)","DOI":"10.14341\/osteo12331"},{"key":"key-10.17116\/stomat202610504163-2","doi-asserted-by":"publisher","DOI":"10.1111\/acel.13983"},{"key":"key-10.17116\/stomat202610504163-3","unstructured":"Gordon LB, Brown WT, Collins FS. Hutchinson-Gilford Progeria Syndrome. 2003 Dec 12 [updated 2023 Oct 19]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024"},{"key":"key-10.17116\/stomat202610504163-4","unstructured":"Laugel V., Adam MP, Feldman J, Mirzaa GM, Cockayne Syndrome. 2000 Dec 28 [updated 2019 Aug 29]. GeneReviews [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024. PMID: 20301516"},{"key":"key-10.17116\/stomat202610504163-5","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-8-9"},{"key":"key-10.17116\/stomat202610504163-6","doi-asserted-by":"publisher","DOI":"10.1038\/s41431-020-0673-1"},{"key":"key-10.17116\/stomat202610504163-7","doi-asserted-by":"publisher","DOI":"10.14341\/probl13369"},{"key":"key-10.17116\/stomat202610504163-8","doi-asserted-by":"publisher","DOI":"10.1038\/s41431-018-0323-z"},{"key":"key-10.17116\/stomat202610504163-9","doi-asserted-by":"publisher","DOI":"10.1038\/s41431-018-0323-z"},{"key":"key-10.17116\/stomat202610504163-10","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2670"},{"key":"key-10.17116\/stomat202610504163-11","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-0419"},{"key":"key-10.17116\/stomat202610504163-12","unstructured":"The Progeria Handbook \u00abA Guide for Families & Health Care Providers of Children with Progeria\u00bb, 2nd Edition.  www.progeriaresearch.org (18.02.2026)"},{"key":"key-10.17116\/stomat202610504163-13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2009.01521.x"},{"key":"key-10.17116\/stomat202610504163-14","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3088"},{"key":"key-10.17116\/stomat202610504163-15","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0351"}],"container-title":["Stomatology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T05:30:50Z","timestamp":1786512650000},"score":1,"resource":{"primary":{"URL":"https:\/\/mediasphera.ru\/issues\/stomatologiya\/2026\/4\/1003917352026041063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,12]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,8,12]]}},"alternative-id":["10.17116\/stomat202610504163"],"URL":"https:\/\/doi.org\/10.17116\/stomat202610504163","relation":{},"ISSN":["0039-1735"],"issn-type":[{"value":"0039-1735","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,12]]}}}