{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T12:08:42Z","timestamp":1779451722454,"version":"3.53.1"},"reference-count":8,"publisher":"Media Sphere Publishing House","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Foren. Med. Expert."],"published-print":{"date-parts":[[2026,5,22]]},"abstract":"<jats:p>This article presents the results of a chemical forensic analysis of medicinal tablets discovered during the archaeological excavation of an ancient burial site in the Rostov region. The aim of the study was to determine the chemical composition of the tablets using a comprehensive set of analytical methods, including high-performance liquid chromatography coupled with time-of-flight mass spectrometry (HPLC-TOF-MS), infrared spectroscopy (FT-IR) and inductively coupled plasma optical emission spectrometry (ICP-OES). An additional objective was to develop a methodological framework for the forensic chemical examination of similar archaeological specimens. Three types of tablets were analyzed. The study outlines sample preparation protocols for each method, analytical conditions, and the results obtained. Morphine, papaverine, and noscapine \u2014 alkaloids of the opium poppy (Papaver somniferum and related species) were identified in all examined samples, along with nicotine. Furthermore, the molecular and elemental composition of one tablet was found to correspond to lead oxychloride (mendipite), a naturally occurring mineral. This investigation represents a unique contribution to forensic medical science and archaeology, as no comparable studies have been previously conducted.<\/jats:p>","DOI":"10.17116\/sudmed20266903129","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T11:33:33Z","timestamp":1779449613000},"page":"29","source":"Crossref","is-referenced-by-count":0,"title":["Chemical forensic analysis of medicinal tablets discovered during excavations of an ancient burial"],"prefix":"10.17116","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6788-2907","authenticated-orcid":false,"given":"A.N.","family":"Prihodko","sequence":"first","affiliation":[{"name":"Bureau of Forensic Medical Examination of the Moscow City Health Department","place":["Moscow, Russia"]},{"name":"Russian Medical Academy of Postgraduate Education Ministry of Health of the Russia","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.Yu.","family":"Svetlolobov","sequence":"additional","affiliation":[{"name":"Bureau of Forensic Medical Examination of the Moscow City Health Department","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2219-5315","authenticated-orcid":false,"given":"S.V.","family":"Shigeev","sequence":"additional","affiliation":[{"name":"Bureau of Forensic Medical Examination of the Moscow City Health Department","place":["Moscow, Russia"]},{"name":"Russian University of Medicine","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0223-2433","authenticated-orcid":false,"given":"P.V.","family":"Pinchuk","sequence":"additional","affiliation":[{"name":"Bureau of Forensic Medical Examination of the Moscow City Health Department","place":["Moscow, Russia"]},{"name":"Pirogov Russian National Research Medical University","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0160-8520","authenticated-orcid":false,"given":"E.V.","family":"Vdovchenkov","sequence":"additional","affiliation":[{"name":"Institute of Oriental Studies of the Russian Academy of Sciences","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9638-0156","authenticated-orcid":false,"given":"N.I.","family":"Shishlina","sequence":"additional","affiliation":[{"name":"State Historical Museum","place":["Moscow, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6743","reference":[{"key":"key-10.17116\/sudmed20266903129-1","unstructured":"Beglov SI, Yatsenko VV. Late Sarmatian burial mound near the Mokry Chaltyr steam. The Crimea during the sarmatian period (2nd century BC \u2014 4th century AD). Sevastopol: Albatros; 2023. (In Russ.)"},{"key":"key-10.17116\/sudmed20266903129-2","unstructured":"Shishlina NI. The northwestern Caspian region in the Bronze age (5th \u2014 3rd mil. BC). GIM; 2007. (In Russ.)"},{"key":"key-10.17116\/sudmed20266903129-3","unstructured":"Sarianidi V. Margiana and Soma-Haoma. Electronic Journal of Vedic Studies (EJVS). 2003;9(1c)"},{"key":"key-10.17116\/sudmed20266903129-4","doi-asserted-by":"publisher","DOI":"10.1663\/0013-0001(2003)057[0295:AEFTTO]2.0.CO;2"},{"key":"key-10.17116\/sudmed20266903129-5","doi-asserted-by":"publisher","DOI":"10.1002\/ansa.202200062"},{"key":"key-10.17116\/sudmed20266903129-6","doi-asserted-by":"publisher","DOI":"10.17116\/sudmed20206302132"},{"key":"key-10.17116\/sudmed20266903129-7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jas.2023.105873"},{"key":"key-10.17116\/sudmed20266903129-8","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2014.09.008"}],"container-title":["Forensic Medical Expertise"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T11:33:44Z","timestamp":1779449624000},"score":1,"resource":{"primary":{"URL":"https:\/\/mediasphera.ru\/issues\/sudebno-meditsinskaya-ekspertiza\/2026\/3\/1003945212026031029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,22]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5,22]]}},"alternative-id":["10.17116\/sudmed20266903129"],"URL":"https:\/\/doi.org\/10.17116\/sudmed20266903129","relation":{},"ISSN":["0039-4521"],"issn-type":[{"value":"0039-4521","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,22]]}}}