{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T20:06:38Z","timestamp":1648584398728},"reference-count":16,"publisher":"Consilium Medicum","issue":"8","license":[{"start":{"date-parts":[[2016,8,15]],"date-time":"2016-08-15T00:00:00Z","timestamp":1471219200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Terapevticheskii arkhiv"],"abstract":"<jats:p>Aim. To comparatively assess desensitization schemes with and without plasmapheresis in patients with low presensitization. Subjects and methods. The investigators studied the efficiency of the two desensitization schemes (cascade plasma filtration + intravenous immunoglobulin used in a dose of 100 mg\/kg in 19 patients (a study group; panel reactive antibodies (PRA) 25.1\u00b16.1%) versus 2 g\/kg in 23 patients (a comparison group, PRA 18.9\u00b14.4%). The crossmatch reaction was negative in both groups. The median follow-up period was 23.5 (quartiles 1 and 3: 10.25 and 26) months. Results. The study group was noted to have 6 episodes of acute rejection and 1 episode of infection; the comparison group had 13 and 3 episodes, respectively. The overall renal graft survival was 79 and 65% in the study and comparison groups, respectively; the 1-year graft survival was 94 and 62%. Graft function was significantly better in the study group: there was a lower daily proteinuria level (p<\/jats:p>","DOI":"10.17116\/terarkh201688867-72","type":"journal-article","created":{"date-parts":[[2016,9,13]],"date-time":"2016-09-13T15:21:04Z","timestamp":1473780064000},"page":"67-72","source":"Crossref","is-referenced-by-count":0,"title":["Renal transplantation in recipients with moderate presensitization"],"prefix":"10.26442","volume":"88","author":[{"given":"A V","family":"Vatazin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A B","family":"Zulkarnaev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18344","published-online":{"date-parts":[[2016,8,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.15825\/1995-1191-2015-2-7-22"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfs089"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13195"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000000469"},{"key":"ref5","unstructured":"\u0411\u0438\u043a\u0431\u043e\u0432 \u0411.\u0422., \u0422\u043e\u043c\u0438\u043b\u0438\u043d\u0430 \u041d.\u0410. \u0417\u0430\u043c\u0435\u0441\u0442\u0438\u0442\u0435\u043b\u044c\u043d\u0430\u044f \u0442\u0435\u0440\u0430\u043f\u0438\u044f \u0431\u043e\u043b\u044c\u043d\u044b\u0445 \u0441 \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u043f\u043e\u0447\u0435\u0447\u043d\u043e\u0439 \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c\u044e \u043c\u0435\u0442\u043e\u0434\u0430\u043c\u0438 \u043f\u0435\u0440\u0438\u0442\u043e\u043d\u0435\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0434\u0438\u0430\u043b\u0438\u0437\u0430 \u0438 \u0442\u0440\u0430\u043d\u0441\u043f\u043b\u0430\u043d\u0442\u0430\u0446\u0438\u0438 \u043f\u043e\u0447\u043a\u0438 \u0432 \u0440\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0444\u0435\u0434\u0435\u0440\u0430\u0446\u0438\u0438 \u0432 1998\u20142011 \u0433. 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