{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T11:29:50Z","timestamp":1659094190535},"reference-count":10,"publisher":"Consilium Medicum","issue":"1","license":[{"start":{"date-parts":[[2017,1,15]],"date-time":"2017-01-15T00:00:00Z","timestamp":1484438400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Terapevticheskii arkhiv"],"abstract":"<jats:p>Aim. To determine the clinical features of skin diseases developing in the presence of metabolic disturbances in patients with chronic diffuse liver diseases. Subjects and methods. A total of 368 patients with different clinical forms of hepatopathy were comprehensively examined. Results. 817 cases of seborrhea, skin itch, xerodermia, xanthomatosis, and dyschromia were detected in 318 (86.4%) patients. Conclusion. The prevalence and intensity of cutaneous manifestations depended on the nature of the pathological liver process and indirectly testified to its severity and activity. The symptoms of skin diseases were most pronounced in patients with autoimmune liver lesions, chronic toxic hepatitis, and cirrhosis.<\/jats:p>","DOI":"10.17116\/terarkh201789149-52","type":"journal-article","created":{"date-parts":[[2017,2,13]],"date-time":"2017-02-13T14:21:57Z","timestamp":1486995717000},"page":"49-52","source":"Crossref","is-referenced-by-count":1,"title":["Clinical features of \u00abmetabolism\u00bb diseases of the skin in patients with chronic diffuse liver diseases"],"prefix":"10.26442","volume":"89","author":[{"given":"O N","family":"Pozdnyakova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O B","family":"Nemchaninova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S G","family":"Lykova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T B","family":"Reshetnikova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18344","published-online":{"date-parts":[[2017,1,15]]},"reference":[{"key":"ref1","unstructured":"\u0413\u0430\u0441\u0442\u0440\u043e\u044d\u043d\u0442\u0435\u0440\u043e\u043b\u043e\u0433\u0438\u044f: \u041d\u0430\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0435 \u0440\u0443\u043a\u043e\u0432\u043e\u0434\u0441\u0442\u0432\u043e. \u041f\u043e\u0434 \u0440\u0435\u0434. \u0418\u0432\u0430\u0448\u043a\u0438\u043d\u0430 \u0410.\u0412., \u041b\u0430\u043f\u0438\u043d\u043e\u0439 \u0422.\u041b. \u041c.: \u0413\u042d\u041e\u0422\u0410\u0420-\u041c\u0435\u0434\u0438\u0430; 2008."},{"key":"ref2","unstructured":"\u041c\u0430\u043b\u044c\u043a\u043e\u0432 \u041f.\u0413., \u0414\u0430\u043d\u0438\u043b\u043e\u0432\u0430 \u041d.\u0412., \u041c\u043e\u0441\u043a\u0432\u0438\u043d\u0430 \u041b.\u0412. \u0412\u043d\u0435\u043f\u0435\u0447\u0435\u043d\u043e\u0447\u043d\u044b\u0435 \u043e\u0441\u043b\u043e\u0436\u043d\u0435\u043d\u0438\u044f \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0432\u0438\u0440\u0443\u0441\u043d\u043e\u0433\u043e \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0430 \u0441 (\u043e\u0431\u0437\u043e\u0440). \u0424\u0443\u043d\u0434\u0430\u043c\u0435\u043d\u0442\u0430\u043b\u044c\u043d\u044b\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f. 2009;5:41-46."},{"key":"ref3","unstructured":"\u0421\u0432\u0435\u0447\u043d\u0438\u043a\u043e\u0432\u0430 \u0415.\u0412., \u0421\u0435\u0440\u0433\u0435\u0435\u0432 \u042e.\u0412. \u0414\u0435\u0440\u043c\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0430\u0441\u043f\u0435\u043a\u0442\u044b \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0432\u0438\u0440\u0443\u0441\u043d\u044b\u0445 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u043e\u0432. \u0421\u043e\u0432\u0440\u0435\u043c\u0435\u043d\u043d\u044b\u0435 \u043f\u0440\u043e\u0431\u043b\u0435\u043c\u044b \u0434\u0435\u0440\u043c\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0438, \u0438\u043c\u043c\u0443\u043d\u043e\u043b\u043e\u0433\u0438\u0438 \u0438 \u0432\u0440\u0430\u0447\u0435\u0431\u043d\u043e\u0439 \u043a\u043e\u0441\u043c\u0435\u0442\u043e\u043b\u043e\u0433\u0438\u0438. 2006;2(2):43-47."},{"key":"ref4","unstructured":"\u0425\u0430\u0444\u0438\u0441\u043e\u0432\u0430 \u041e.\u041e., \u041c\u0430\u0437\u0443\u0440\u0447\u0438\u043a \u041d.\u0412., \u041d\u0438\u044f\u0437\u043e\u0432 \u0410.\u0420., \u041e\u0433\u0443\u0440\u0446\u043e\u0432 \u041f.\u041f. \u041a\u043e\u0436\u043d\u044b\u0435 \u043f\u0440\u043e\u044f\u0432\u043b\u0435\u043d\u0438\u044f \u043f\u0440\u0438 \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u043c \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0435 \u0421. \u0412\u0435\u0441\u0442\u043d\u0438\u043a \u043f\u043e\u0441\u043b\u0435\u0434\u0438\u043f\u043b\u043e\u043c\u043d\u043e\u0433\u043e \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u043e\u0433\u043e \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u043d\u0438\u044f. 2014;1:13-15."},{"key":"ref5","unstructured":"\u041a\u043e\u0440\u043e\u0442\u0430\u0435\u0432\u0430 \u0418.\u0410., \u0421\u043a\u043b\u044f\u0440 \u041b.\u0424., \u0421\u0438\u043c\u0430\u043a\u043e\u0432\u0430 \u0410.\u0418., \u0421\u0438\u043d\u0433\u0443\u0440 \u041b.\u0413., \u041f\u043e\u043f\u043e\u0432 \u0410.\u0424. \u041f\u0441\u043e\u0440\u0438\u0430\u0437 \u0438 \u043f\u043e\u0437\u0434\u043d\u044f\u044f \u043a\u043e\u0436\u043d\u0430\u044f \u043f\u043e\u0440\u0444\u0438\u0440\u0438\u044f, \u0430\u0441\u0441\u043e\u0446\u0438\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u0430\u044f \u0441 \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u043c \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u043e\u043c \u0421 \u043f\u0440\u0438 \u0412\u0418\u0427-\u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0438 (\u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u043d\u0430\u0431\u043b\u044e\u0434\u0435\u043d\u0438\u044f). \u0412\u0435\u0441\u0442\u043d\u0438\u043a \u0434\u0435\u0440\u043c\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0438 \u0438 \u0432\u0435\u043d\u0435\u0440\u043e\u043b\u043e\u0433\u0438\u0438. 2015;4:90-94."},{"key":"ref6","unstructured":"\u041c\u0430\u043d\u0442\u0443\u043b\u0430 \u0410.\u0410. \u041e\u0441\u043e\u0431\u0435\u043d\u043d\u043e\u0441\u0442\u0438 \u0434\u0435\u0440\u043c\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u043f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0438 \u0443 \u0431\u043e\u043b\u044c\u043d\u044b\u0445 \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u043c\u0438 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0430\u043c\u0438. \u0414\u0435\u0440\u043c\u0430\u0442\u043e\u043b\u043e\u0433i\u044f \u0442\u0430 \u0432\u0435\u043d\u0435\u0440\u043e\u043b\u043e\u0433i\u044f. 2009;4(46):41-45."},{"key":"ref7","unstructured":"\u0411\u0443\u0442\u0430\u0440\u0435\u0432\u0430 \u041c.\u041c., \u0416\u0438\u043b\u043e\u0432\u0430 \u041c.\u0411. \u041a\u0440\u0430\u0441\u043d\u044b\u0439 \u043f\u043b\u043e\u0441\u043a\u0438\u0439 \u043b\u0438\u0448\u0430\u0439, \u0430\u0441\u0441\u043e\u0446\u0438\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0439 \u0441 \u0432\u0438\u0440\u0443\u0441\u043d\u044b\u043c \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u043e\u043c \u0421 \u2014 \u043e\u0441\u043e\u0431\u0435\u043d\u043d\u043e\u0441\u0442\u0438 \u0442\u0435\u0440\u0430\u043f\u0438\u0438. \u0412\u0435\u0441\u0442\u043d\u0438\u043a \u0434\u0435\u0440\u043c\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0438 \u0438 \u0432\u0435\u043d\u0435\u0440\u043e\u043b\u043e\u0433\u0438\u0438. 2010;1:105-108."},{"key":"ref8","unstructured":"\u0411\u0430\u043a\u0441\u0442\u043e\u043d \u041f. \u0414\u0435\u0440\u043c\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u044f. \u041f\u0435\u0440. \u0441 \u0430\u043d\u0433\u043b. \u041c.: \u00ab\u0411\u0418\u041d\u041e\u041c\u00bb; 2005."},{"key":"ref9","unstructured":"\u0412\u0443\u043b\u044c\u0444 \u041a., \u0414\u0436\u043e\u043d\u0441\u043e\u043d \u0420., \u0421\u044e\u0440\u043c\u043e\u043d\u0434 \u0414. \u0414\u0435\u0440\u043c\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u044f \u043f\u043e \u0422\u043e\u043c\u0430\u0441\u0443 \u0424\u0438\u0446\u043f\u0430\u0442\u0440\u0438\u043a\u0443. \u0410\u0442\u043b\u0430\u0441-\u0441\u043f\u0440\u0430\u0432\u043e\u0447\u043d\u0438\u043a. \u0412\u0442\u043e\u0440\u043e\u0435 \u0440\u0443\u0441\u0441\u043a\u043e\u0435 \u0438\u0437\u0434\u0430\u043d\u0438\u0435. \u041f\u0435\u0440. \u0441 \u0430\u043d\u0433\u043b. \u041c.: \u041f\u0440\u0430\u043a\u0442\u0438\u043a\u0430; 2007."},{"key":"ref10","unstructured":"\u041c\u044f\u0434\u0435\u043b\u0435\u0446 \u041e.\u0414., \u0410\u0434\u0430\u0441\u043a\u0435\u0432\u0438\u0447 \u0412.\u041f. \u0424\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u0430\u044f \u043c\u043e\u0440\u0444\u043e\u043b\u043e\u0433\u0438\u044f \u0438 \u043e\u0431\u0449\u0430\u044f \u043f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u044f \u043a\u043e\u0436\u0438. \u0412\u0438\u0442\u0435\u0431\u0441\u043a: \u0418\u0437\u0434\u0430\u0442\u0435\u043b\u044c\u0441\u0442\u0432\u043e \u0412\u0438\u0442\u0435\u0431\u0441\u043a\u043e\u0433\u043e \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u043e\u0433\u043e \u0438\u043d\u0441\u0442\u0438\u0442\u0443\u0442\u0430; 1997."}],"container-title":["Terapevticheskii 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