{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T01:06:45Z","timestamp":1649466405807},"reference-count":44,"publisher":"Consilium Medicum","issue":"3","license":[{"start":{"date-parts":[[2017,3,15]],"date-time":"2017-03-15T00:00:00Z","timestamp":1489536000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Terapevticheskii arkhiv"],"abstract":"<jats:p>Aim. To investigate the prognostic value of serum N-terminal pro-brain natriuretic peptide (NT-proBNP) in the development of acute kidney injury (AKI) in patients with acute decompensated chronic heart failure (ADCHF). Subjects and methods. Eighty-three patients (55 (66%) men and 28 (34%) women; mean age, 65\u00b111 years) with ADCHF were examined. AKI was diagnosed and classified according to the 2012 Kidney Disease Improving Global Outcomes Clinical Practice guidelines. To rule out contrast-induced AKI, the investigation enrolled only patients in whom radiopague agents had not been injected 7 days before and during hospitalization. Enzyme immunoassay was used to determine serum NT-proBNP concentrations in all the patients upon hospital admission. Results. AKI was diagnosed in 18 (22%) patients, 13 (16%) had Stage I, 4 (5%) had Stage II, and 1 (1%) had Stage III. The serum concentration of NT-proBNP was significantly higher in patients with AKI than that in the other patients [1512.1 (981.0; 2246.2) and 861.8 (499.0; 1383.6) pg\/ml (p=0.008). The rise in NT-proBNP concentrations of more than 942 pg\/ml was established to be associated with a considerable increase in the risk of AKI (relative risk (RR) was 4.3; 95% confidence interval (CI), 1.27\u201414.90; p=0.02). R\u041e\u0421 analysis indicated that a NT-proBNP level of &gt;942 pg\/ml allows prediction of AKI with a sensitivity of 78% (52; 94) and a specificity of 55% (44; 69) (AUC=0.70; p=0.006). Four (5%) patients died in hospital. NT-proBNP levels in all the dead were greater than 942 pg\/ml. Two of the 4 deceased patients had AKI. Conclusion. A high level of NT-proBNP in a patient with ADCHF during hospitalization can serve as a biomarker for high risk of AKI and for high mortality rates.<\/jats:p>","DOI":"10.17116\/terarkh201789378-84","type":"journal-article","created":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T10:05:54Z","timestamp":1490263554000},"page":"78-84","source":"Crossref","is-referenced-by-count":3,"title":["Value of N-terminal pro brain natriuretic peptide in predicting acute kidney injury in patients with acute decompensated chronic heart failure"],"prefix":"10.26442","volume":"89","author":[{"given":"M V","family":"Menzorov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A M","family":"Shutov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V I","family":"Midlenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N V","family":"Larionova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I V","family":"Morozova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O V","family":"Akulova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18344","published-online":{"date-parts":[[2017,3,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000339789"},{"key":"ref2","unstructured":"\u0421\u043c\u0438\u0440\u043d\u043e\u0432 \u0410.\u0412., \u0414\u043e\u0431\u0440\u043e\u043d\u0440\u0430\u0432\u043e\u0432 \u0412.\u0410., \u0420\u0443\u043c\u044f\u043d\u0446\u0435\u0432 \u0410.\u0428., \u041a\u0430\u044e\u043a\u043e\u0432 \u0410.\u0413. \u041e\u0441\u0442\u0440\u043e\u0435 \u043f\u043e\u0432\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u0435 \u043f\u043e\u0447\u0435\u043a. \u041c.: \u041c\u0418\u0410; 2015."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/479730"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-007-0754-4"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfn300"},{"key":"ref6","unstructured":"\u041c\u0430\u0440\u0435\u0435\u0432 \u0412.\u042e., \u0410\u0433\u0435\u0435\u0432 \u0424.\u0422., \u0410\u0440\u0443\u0442\u044e\u043d\u043e\u0432 \u0413.\u041f., \u041a\u043e\u0440\u043e\u0442\u0435\u0435\u0432 \u0410.\u0412., \u041c\u0430\u0440\u0435\u0435\u0432 \u042e.\u0412., \u041e\u0432\u0447\u0438\u043d\u043d\u0438\u043a\u043e\u0432 \u0410.\u0413. \u041d\u0430\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u044b\u0435 \u0440\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0430\u0446\u0438\u0438 \u041e\u0421\u0421\u041d, \u0420\u041a\u041e \u0438 \u0420\u041d\u041c\u041e\u0422 \u043f\u043e \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0435 \u0438 \u043b\u0435\u0447\u0435\u043d\u0438\u044e \u0425\u0421\u041d (\u0447\u0435\u0442\u0432\u0435\u0440\u0442\u044b\u0439 \u043f\u0435\u0440\u0435\u0441\u043c\u043e\u0442\u0440). \u0421\u0435\u0440\u0434\u0435\u0447\u043d\u0430\u044f \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c. 2013; 7(81):379-472."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2369-13-51"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1253\/circj.cj-12-0994"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.17650\/1818-8338-2013-2-29-33"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2004.08.005"},{"key":"ref11","unstructured":"\u041c\u0435\u043d\u0437\u043e\u0440\u043e\u0432 \u041c.\u0412., \u0428\u0443\u0442\u043e\u0432 \u0410.\u041c. \u041b\u0438\u043f\u043e\u043a\u0430\u0438\u043d, \u0430\u0441\u0441\u043e\u0446\u0438\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0439 \u0441 \u0436\u0435\u043b\u0430\u0442\u0438\u043d\u0430\u0437\u043e\u0439 \u043d\u0435\u0439\u0442\u0440\u043e\u0444\u0438\u043b\u043e\u0432 \u0432 \u043f\u0440\u043e\u0433\u043d\u043e\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0438 \u043e\u0441\u0442\u0440\u043e\u0433\u043e \u043f\u043e\u0432\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u044f \u043f\u043e\u0447\u0435\u043a \u0443 \u0431\u043e\u043b\u044c\u043d\u044b\u0445 \u0441 \u043e\u0441\u0442\u0440\u044b\u043c \u043a\u043e\u0440\u043e\u043d\u0430\u0440\u043d\u044b\u043c \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u043e\u043c. \u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430. 2014;92(3):54-58."},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2261-12-8"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2013.07.004"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/cc13752"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfs380"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159\/000349964"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gft510"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.07.051"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2007.01454.x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2008.07.014"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi859"},{"key":"ref22","unstructured":"\u041c\u0435\u043d\u0437\u043e\u0440\u043e\u0432 \u041c.\u0412., \u0428\u0443\u0442\u043e\u0432 \u0410.\u041c., \u041c\u0430\u043a\u0435\u0435\u0432\u0430 \u0415.\u0420. \u0438 \u0434\u0440. \u0421\u043b\u043e\u0436\u043d\u043e\u0441\u0442\u0438 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u043e\u0441\u0442\u0440\u043e\u0433\u043e \u043f\u043e\u0432\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u044f \u043f\u043e\u0447\u0435\u043a \u0443 \u0431\u043e\u043b\u044c\u043d\u044b\u0445 \u0438\u043d\u0444\u0430\u0440\u043a\u0442\u043e\u043c \u043c\u0438\u043e\u043a\u0430\u0440\u0434\u0430 \u0441 \u043f\u043e\u0434\u044a\u0435\u043c\u043e\u043c \u0441\u0435\u0433\u043c\u0435\u043d\u0442\u0430 ST. \u0422\u0435\u0440. \u0430\u0440\u0445\u0438\u0432. 2014; 86(4):25-29."},{"key":"ref23","unstructured":"\u041c\u0435\u043d\u0437\u043e\u0440\u043e\u0432 \u041c.\u0412., \u0428\u0443\u0442\u043e\u0432 \u0410.\u041c., \u0428\u0443\u0442\u043e\u0432 \u0410.\u041c., \u041b\u0443\u043a\u044c\u044f\u043d\u043e\u0432\u0430 \u0412.\u0410., \u0413\u0435\u0440\u0434\u0442 \u0410.\u041c., \u0413\u0440\u0438\u0448\u0435\u043d\u044c\u043a\u0438\u043d \u0418.\u042e. \u041e\u0441\u0442\u0440\u043e\u0435 \u043f\u043e\u0432\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u0435 \u043f\u043e\u0447\u0435\u043a \u0443 \u0431\u043e\u043b\u044c\u043d\u044b\u0445 \u0441 \u0438\u043d\u0441\u0443\u043b\u044c\u0442\u043e\u043c. \u041d\u0435\u0444\u0440\u043e\u043b\u043e\u0433\u0438\u044f. 2014;18(2):55-60."},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.3265\/Nefrologia.pre2011.Sep.10988"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.04.017"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2015.03.043"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1681\/asn.2006010063"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181b9eb3b"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2002.125623"},{"key":"ref30","unstructured":"\u0421\u0430\u043f\u0440\u044b\u0433\u0438\u043d \u0414.\u0411., \u041c\u043e\u0448\u0438\u043d\u0430 \u0412.\u0410. \u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435 \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u044f \u043c\u043e\u0437\u0433\u043e\u0432\u043e\u0433\u043e \u043d\u0430\u0442\u0440\u0438\u0439\u0443\u0440\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043f\u0435\u043f\u0442\u0438\u0434\u0430 (\u0430\u043c\u0438\u043d\u043e\u0442\u0435\u0440\u043c\u0438\u043d\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0444\u0440\u0430\u0433\u043c\u0435\u043d\u0442\u0430) \u2014 NT proBNP, \u043f\u0440\u0438 \u043a\u0430\u0440\u0434\u0438\u043e\u0432\u0430\u0441\u043a\u0443\u043b\u044f\u0440\u043d\u043e\u0439 \u043f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0438. \u041b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u043d\u0430\u044f \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430. 2003;8:1-8."},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000054164.99881.00"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2004.01.004"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0796fje"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1590\/s0004-27302006000200006"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199807303390507"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2003.152"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.071233"},{"key":"ref38","unstructured":"Ruan ZB, Zhu L, Yin YG, Chen GC. Cystatin C, N-terminal probrain natriuretic peptides and outcomes in acute heart failure with acute kidney injury in a 12-month follow-up: Insights into the cardiorenal syndrome. J Res Med Sci. 2014;19(5):404-409."},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2014-0191"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/951629"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2015.10.015"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2013.01.014"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2003.026138"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2005.10.011"}],"container-title":["Terapevticheskii arkhiv"],"original-title":[],"link":[{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/viewFile\/32218\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/viewFile\/32218\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T23:40:13Z","timestamp":1634082013000},"score":1,"resource":{"primary":{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/view\/32218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,15]]},"references-count":44,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,3,15]]}},"URL":"https:\/\/doi.org\/10.17116\/terarkh201789378-84","relation":{},"ISSN":["2309-5342","0040-3660"],"issn-type":[{"value":"2309-5342","type":"electronic"},{"value":"0040-3660","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3,15]]}}}