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Torasemide is the most effective and safe loop diuretic with the optimal pharmacokinetic profile, the additional properties associated with simultaneous blockade of the renin-angiotensin-aldosterone system and with the antiadrenergic effects of the drug, its positive impact on myocardial fibrosis and minimal severe potential negative effects. Sustained-release torasemide provides a more comfortable removal of excess liquid and does not deteriorate quality of life.<\/jats:p>","DOI":"10.17116\/terarkh2017899115-119","type":"journal-article","created":{"date-parts":[[2017,10,17]],"date-time":"2017-10-17T11:06:24Z","timestamp":1508238384000},"page":"115-119","source":"Crossref","is-referenced-by-count":5,"title":["Use of loop diuretics in heart failure: Current aspects"],"prefix":"10.26442","volume":"89","author":[{"given":"N V","family":"Kurlykina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E M","family":"Seredenina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y\u0430 A","family":"Orlova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18344","published-online":{"date-parts":[[2017,9,15]]},"reference":[{"key":"key-10.17116\/terarkh2017899115-119-1","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.109.192064"},{"key":"key-10.17116\/terarkh2017899115-119-2","unstructured":"Mareev VYu, Ageev FT, Arutyunov GP , Koroteev AV, Mareev YuV, Ovchinnikov AG, Belenkov YuN, Vasyuk YuA, Galyavich AS, Garganeeva AA, Gilyarevskii SR, Glezer MG, Koziolova NA, Kots YaI, Lopatin YuM, Martynov AI, Moiseev VS, Revishvili ASh, Sitnikova MYu, Skibitskii VV, Sokolov EI, Storozhakov GI, Fomin IV, Chesnikova AI, Shlyakhto EV, Akchurin RS, Aronov DM, Arkhipov MV, Bart BYa, Belousov YuB, Boitsov SA, Gendlin GE, Golikov AP, Golitsyn SP, Gurevich MA, Danielyan MO, Dovgalevskii PYa, Zadionchenko VS, Karpov RS, Karpov YuA, Kobalava ZhD, Kuznetsov VA, Lazebnik LB, Nasonov EL, Nedogoda SV, Nikitin YuP, Oganov RG, Panchenko EP, Perepech NB, Podzolkov VI, Pozdnyakov YuA, Rakov AL, Ruda MYa, Rylova AK, Simonenko VB, Sidorenko BA, Staroverov II, Sulimov VA, Tarlovskaya EI, Tereshchenko SN, Fomina IG, Chazova IE, Drapkina OM. 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