{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:41:14Z","timestamp":1790163674839,"version":"4.1.0"},"reference-count":0,"publisher":"Association of Basic Medical Sciences of FBIH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bosn J of Basic Med Sci"],"abstract":"<jats:p>Calcium hydroxide\u00a0has a hard tissue inducing effect. It is a powder, that can be mixed with a physiological saline to a paste. The paste is highly alkaline with a pH 12.5 and its\u00a0application\u00a0to the pulp results in necrosis of the part of coronal pulp tissue shows no or only a milled inflammatory reaction. Analyzing the pH and the concentration of\u00a0calcium\u00a0ions in the periapical area, it is obvious that at least 2 weeks are necessary for\u00a0calcium hydroxide\u00a0bactericide activity.\u00a0Calcium hydroxide\u00a0retains its anti-bacterial properties for about two months when placed under a restoration, after which it degrades to\u00a0calcium\u00a0oxide and other less effective\u00a0calcium\u00a0salts. All\u00a0calcium hydroxide\u00a0preparations have a limited shelf life as they eventually turn into\u00a0calciumoxide.\u00a0Calcium hydroxide\u00a0can be used as linings, for indirect and direct pulp cupping, root dressing, root canal sealant, apical closure. The vehicles play a supportive role, giving pastes chemical characteristics such as dissociation and diffusion as well as favoring the correct filling of the root canal which are decisive factors for antimicrobial potential and tissue healing. The mechanism of action of\u00a0calcium hydroxide\u00a0on tissues, inducing the deposition of mineralized tissue, is an extremely important aspect for the indication of\u00a0calcium hydroxide, because it demonstrates biological compatibility of\u00a0calcium hydroxide.<\/jats:p>","DOI":"10.17305\/bjbms.2003.3488","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T23:12:26Z","timestamp":1527721946000},"page":"26-29","source":"Crossref","is-referenced-by-count":10,"title":["Clinical application of calcium hydroxide in dental pathology and endodontics"],"prefix":"10.17305","volume":"3","author":[{"given":"Amela","family":"La\u010devi\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edina","family":"Vrani\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irfan","family":"Zuli\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6922","published-online":{"date-parts":[[2003,11,20]]},"container-title":["Bosnian Journal of Basic Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3488\/1031","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3488\/1031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T20:27:41Z","timestamp":1578342461000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/view\/3488"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,11,20]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,5,5]]}},"URL":"https:\/\/doi.org\/10.17305\/bjbms.2003.3488","relation":{},"ISSN":["1840-4812","1512-8601"],"issn-type":[{"value":"1840-4812","type":"electronic"},{"value":"1512-8601","type":"print"}],"subject":[],"published":{"date-parts":[[2003,11,20]]}}}