{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T11:21:34Z","timestamp":1648984894250},"reference-count":0,"publisher":"Association of Basic Medical Sciences of FBIH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bosn J of Basic Med Sci"],"abstract":"<jats:p>Down syndrome\u00a0is a genetic state characterized by trisomy of chromosome 21. In the retrospective study for 12 years period (1991-2002) we have conducted\u00a0correlation\u00a0between\u00a0cytogenetics\u00a0analyses and\u00a0clinical findings\u00a0in our centre at 96 male and 83 female patients.\u00a0Down syndrome\u00a0was confirmed by\u00a0cytogenetics\u00a0analyses in 84 (87.5%) male patients and excluded in 12 (12.5%) male patients. Most common karyotype is free trisomy found in 139 (89.7%) examinees, than follows translocation form determined in 9 (5.8%), and mosaicism determined in 7 (4.5%) examinees. Our results indicate that\u00a0cytogenetics\u00a0analyses are necessary to confirm\u00a0diagnosis\u00a0of\u00a0Down syndrome.<\/jats:p>","DOI":"10.17305\/bjbms.2005.3236","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T23:17:01Z","timestamp":1527722221000},"page":"61-67","source":"Crossref","is-referenced-by-count":0,"title":["Cytogenetic findings at Down syndrome and their correlation with clinical findings"],"prefix":"10.17305","volume":"5","author":[{"given":"Amra","family":"\u0106atovi\u0107","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sulejman","family":"Kendi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6922","published-online":{"date-parts":[[2005,11,20]]},"container-title":["Bosnian Journal of Basic Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3236\/908","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3236\/908","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T20:34:37Z","timestamp":1578342877000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/view\/3236"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11,20]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,3,5]]}},"URL":"https:\/\/doi.org\/10.17305\/bjbms.2005.3236","relation":{},"ISSN":["1840-4812","1512-8601"],"issn-type":[{"value":"1840-4812","type":"electronic"},{"value":"1512-8601","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11,20]]}}}