{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T19:11:38Z","timestamp":1648753898256},"reference-count":0,"publisher":"Association of Basic Medical Sciences of FBIH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bosn J of Basic Med Sci"],"abstract":"<jats:p>The aim of this study were to determine which\u00a0antipsychotic\u00a0are currently in use, to establish which doses are administrated to\u00a0patients, to find out is there a practice of proscribing simultaneously more then one\u00a0antipsychotic\u00a0drug, to determine whether\u00a0antipsychotic\u00a0are proscribed in divided doses, to establish whether there is, besides\u00a0antipsychotics,\u00a0treatment\u00a0with other medicaments (co-administration), especially with antiparkinsonics. The research (study) is epidemiological-clinical prospective, descriptive and analytical and it was conducted at University hospitals in Sarajevo, Tuzla and Mostar. Criteria for inclusion, non-inclusion and exclusion from the study were precisely defined as a mean for formation of sample. Based on this hypothesis were established, zero and alterative. According to zero hypothesis in the\u00a0treatment\u00a0of schizophrenia at University hospitals in FBiH new\u00a0antipsychotic\u00a0drugs are in use, small doses are proscribed (up to 20 mg), not more then one\u00a0antipsychotic\u00a0drug is used simultaneously,\u00a0antipsychotics\u00a0are administrated once a day and alongside with\u00a0antipsychotics\u00a0other medicaments are not co-administrated, especially antiparkinsons. The results of our study are showing that majority of\u00a0patients\u00a0are treated with classical\u00a0antipsychotics. Minority of\u00a0patients\u00a0is treated with atypical neuroleptics like olanzapine, which is proscribed only in Sarajevo. Use of risperidone and ziprasidone is registered also only in Sarajevo, but only small number of\u00a0patients\u00a0is treated with these drugs. Most frequent\u00a0antipsychotics\u00a0were promazine and haloperidol. The range between minimal and maximal daily dose of promazine was from 50 to 450 mg\/daily, and for haloperidol from 1 to 75 mg\/daily. Above-mentioned drugs were administrated in an average from two to three times a day. Alongside with\u00a0antipsychotics, other drugs were used. Most frequent was the use of biperidine in oral and parenteral formulation, as well as nitrazepam and diazepam. The importance of this study is following: data are useful for the current mental health care reform in FBiH, results will point out place and position of FBiH in contemporary world trends in the\u00a0treatment\u00a0of schizophrenia, they will contribute to rational use of\u00a0antipsychotic\u00a0therapy, they will point out possible ways in reduction of side effects, often dangerous adverse effects of\u00a0antipsychotics, and they will give contribution to faster rehabilitation of schizophrenics with the reduction of financial means for the\u00a0treatment\u00a0of\u00a0patients\u00a0with schizophrenia.<\/jats:p>","DOI":"10.17305\/bjbms.2005.3238","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T23:17:01Z","timestamp":1527722221000},"page":"78-83","source":"Crossref","is-referenced-by-count":0,"title":["Models of treatment with antipsychotics of the schizophrenic patients"],"prefix":"10.17305","volume":"5","author":[{"given":"Svjetlana","family":"Loga-Zec","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irfan","family":"Zuli\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ned\u017ead","family":"Mulabegovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Slobodan","family":"Loga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saida","family":"Fi\u0161ekovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasna","family":"Kusturica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6922","published-online":{"date-parts":[[2005,11,20]]},"container-title":["Bosnian Journal of Basic Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3238\/910","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3238\/910","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T20:34:36Z","timestamp":1578342876000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/view\/3238"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11,20]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,3,5]]}},"URL":"https:\/\/doi.org\/10.17305\/bjbms.2005.3238","relation":{},"ISSN":["1840-4812","1512-8601"],"issn-type":[{"value":"1840-4812","type":"electronic"},{"value":"1512-8601","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11,20]]}}}