{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,10,3]],"date-time":"2022-10-03T16:50:15Z","timestamp":1664815815061},"reference-count":0,"publisher":"Association of Basic Medical Sciences of FBIH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bosn J of Basic Med Sci"],"abstract":"<jats:p>Innocent\u00a0heart murmurs\u00a0are hearth\u00a0murmurs\u00a0that occur in patients with a normal\u00a0heart\u00a0structure. They do not represent a disease of the\u00a0heartand vascular system, and should not be treated as such. Iron-deficiency\u00a0anaemia\u00a0often causes, along with other symptoms, systolic\u00a0heart murmurs\u00a0and tachycardia. It appears in children of all ages representing a most common haematological paediatric disease. To establish the influence of iron-deficiency\u00a0anaemia\u00a0on genesis of innocent\u00a0murmurs\u00a0and to compare auscultatory and phono-electrocardiographic findings in patients with\u00a0anaemia\u00a0and\u00a0heart murmurs\u00a0before and after iron therapy. The study includes 120 patients with innocent\u00a0heart murmurs\u00a0that have been auscultated at cardio-rheumatic outpatient department of\u00a0Pediatric\u00a0Clinic of the Clinical Center of the University of Sarajevo, during the period from 01\/01\/2004 to 31\/12\/2004. Further diagnostic procedure, i.e. laboratory tests, diagnosed iron-deficiency\u00a0anaemia\u00a0in 30\/120 patients. These patients have been followed in this study. 22\/30 patients had systolic\u00a0murmur\u00a0I\/II intensity of Levin scale; 8\/30 patients had II\/VI systolic\u00a0murmurs\u00a0of intensity by Levin. The highest number of examinees had 0-1 years of age, and in this group the number of boys was higher than the number of girls (M: F = 12:4). During the auscultatory and phono-ECG examinations of\u00a0murmurs, 6 patients had haemoglobin values less than 95 g\/l, which corresponds to an average and severe type of\u00a0anaemia. 24 patients had haemoglobin values between 95 and 110 g\/l, which corresponds to benign type of\u00a0anaemia. The most numerous were patients aged between 0 - 1 year (3 patients with hemoglobin value Hb &lt; 95 g\/l, 13 patients with hemoglobin value Hb 95-110 g\/l). All patients were treated with iron medicaments. After three months, clinical and laboratory re-evaluation was performed and it has demonstrated that after iron therapy 24 patients had level of a haemoglobin Hb &gt;110 g\/l and 6 patients had haemoglobin levels between 95 and 110 g\/l. By auscultatory and phono-ECG examinations,\u00a0murmurs\u00a0of a level of intensity I\/II was registered in only one child, while in the other 29 patients there were not any registered\u00a0heart murmurs. Diagnosis of\u00a0anaemia\u00a0in the paediatric\u00a0population\u00a0group delays definitive diagnosis of\u00a0heart murmurs. Innocent\u00a0murmurs\u00a0in children with sideropenic\u00a0anaemia\u00a0occur as its consequence. After adequately conducted iron therapy, i.e. cured\u00a0anaemia,\u00a0heart murmurs\u00a0were not auscultated.\u00a0\u00a0<\/jats:p>","DOI":"10.17305\/bjbms.2005.3269","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T23:18:35Z","timestamp":1527722315000},"page":"39-45","source":"Crossref","is-referenced-by-count":2,"title":["Heart Murmur and Anaemia in the Pediatric Population"],"prefix":"10.17305","volume":"5","author":[{"given":"Senka","family":"Mesihovi\u0107-Dinarevi\u0107","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasna","family":"Ibrahimovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edo","family":"Hasanbegovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emina","family":"I\u0107indi\u0107-Naka\u0161","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aida","family":"Smaji\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6922","published-online":{"date-parts":[[2008,8,20]]},"container-title":["Bosnian Journal of Basic Medical Sciences"],"original-title":[],"link":[{"URL":"http:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3269\/919","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3269\/919","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T13:05:54Z","timestamp":1554296754000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/view\/3269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8,20]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,4,1]]}},"URL":"https:\/\/doi.org\/10.17305\/bjbms.2005.3269","relation":{},"ISSN":["1840-4812","1512-8601"],"issn-type":[{"value":"1840-4812","type":"electronic"},{"value":"1512-8601","type":"print"}],"subject":[],"published":{"date-parts":[[2008,8,20]]}}}