{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T17:48:59Z","timestamp":1722275339875},"reference-count":0,"publisher":"Association of Basic Medical Sciences of FBIH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bosn J of Basic Med Sci"],"abstract":"<jats:p>Turner Syndrome\u00a0is a genetic condition in females that results from an abnormal chromosome. One of the X chromosomes is missing or misshapen in the most cells of the body. Three classics\u00a0clinical\u00a0symptoms\u00a0of the\u00a0syndrome\u00a0are: incomplete sexual maturation, short stature and pterygium colli.\u00a0Turner Syndrome\u00a0is diagnosed by karyotyping. In the retrospective study for a twelve years period (1991-2002)\u00a0correlation\u00a0between\u00a0clinical\u00a0and\u00a0cytogenetics\u00a0findings\u00a0was established in our Center among 47 examinees from all parts of Federation of Bosnia and Herzegovina, who had suspect\u00a0clinical\u00a0diagnosis\u00a0of\u00a0Turner Syndrome. The\u00a0syndrome\u00a0was demonstrated by\u00a0cytogeneticsexaminations in 30(63,8%) examinees and excluded in 17 (36,2%) examinees. The most frequent karyotype is monosomy of X chromosome (45,X) found at 63,3%, than isochromosome of Xq (46,XisoXq) found at 16,7%, mosaic form (46,XX\/45,X) and deletion of Xp (46,XdelXp) both at 6,7%, than deletion of Xq (46,XdelXq) and ring of Xp (46,XX\/46,XringXp) both at 3,3%. Our results suggest that promptly and exactly\u00a0diagnosis\u00a0of\u00a0Turner syndrome\u00a0is very important due to introducing growth hormone therapy and estrogen therapy at a very young age.<\/jats:p>","DOI":"10.17305\/bjbms.2005.3271","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T23:14:23Z","timestamp":1527722063000},"page":"54-58","source":"Crossref","is-referenced-by-count":5,"title":["Cytogenetics findings at Turner Syndrome and their correlation with clinical findings"],"prefix":"10.17305","volume":"5","author":[{"given":"Amra","family":"\u0106atovi\u0107","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sulejman","family":"Kendi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6922","published-online":{"date-parts":[[2005,8,20]]},"container-title":["Bosnian Journal of Basic Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3271\/921","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3271\/921","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T20:34:52Z","timestamp":1578342892000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/view\/3271"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8,20]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,4,1]]}},"URL":"https:\/\/doi.org\/10.17305\/bjbms.2005.3271","relation":{},"ISSN":["1840-4812","1512-8601"],"issn-type":[{"value":"1840-4812","type":"electronic"},{"value":"1512-8601","type":"print"}],"subject":[],"published":{"date-parts":[[2005,8,20]]}}}