{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T20:00:13Z","timestamp":1759694413813},"reference-count":0,"publisher":"Association of Basic Medical Sciences of FBIH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bosn J of Basic Med Sci"],"abstract":"<jats:p>Serum\u00a0and\u00a0tissue\u00a0angiotensin-converting enzyme\u00a0(ACE) was measured in 20\u00a0patients\u00a0with\u00a0lichen planus\u00a0before and after therapy, and in 20 healthy individuals.\u00a0Serum\u00a0and\u00a0tissue\u00a0ACE activity was determined by spectrophotometric method using hippuryl-l-histidyl-l-leucine as a substrate. The\u00a0enzyme\u00a0activity is expressed in the following units: 1 U corresponds to 1 nmol of hippuric acid released by hydrolysis of hippuryl-l-histidyl-l-leucine per minute and one liter of\u00a0serum\u00a0or 50 mg\u00a0tissue. Before therapy,\u00a0serum\u00a0ACE activity was significantly increased in\u00a0patients\u00a0with\u00a0lichen planus\u00a0(35.9 +\/- 2.33 U\/L) in comparison to healthy individuals (28.16 +\/- 1.7 U\/L).\u00a0Tissue\u00a0ACE activity was increased in\u00a0patients\u00a0with\u00a0lichen planus\u00a0(2.24 +\/- 0.41 U\/50 mg) in comparison to healthy individuals (1.86 +\/- 0.16 U\/50 mg), but the difference was not significant. After therapy,\u00a0serum\u00a0and\u00a0tissue\u00a0ACE activity decreased and no significant difference in ACE activity was found. The determination of\u00a0serum\u00a0ACE activity may be a good non-specific parameter for the assessment of therapeutic effects.<\/jats:p>","DOI":"10.17305\/bjbms.2005.3272","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T23:14:23Z","timestamp":1527722063000},"page":"59-62","source":"Crossref","is-referenced-by-count":4,"title":["Serum and tissue angiotensin converting enzyme in patients with lichen planus"],"prefix":"10.17305","volume":"5","author":[{"given":"Faruk","family":"Alendar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasminko","family":"Huski\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nermina","family":"Babi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ned\u017ead","family":"Mulabegovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6922","published-online":{"date-parts":[[2005,8,20]]},"container-title":["Bosnian Journal of Basic Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3272\/922","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/download\/3272\/922","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T20:34:51Z","timestamp":1578342891000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bjbms.org\/ojs\/index.php\/bjbms\/article\/view\/3272"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8,20]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,4,1]]}},"URL":"https:\/\/doi.org\/10.17305\/bjbms.2005.3272","relation":{},"ISSN":["1840-4812","1512-8601"],"issn-type":[{"value":"1840-4812","type":"electronic"},{"value":"1512-8601","type":"print"}],"subject":[],"published":{"date-parts":[[2005,8,20]]}}}