{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T10:33:04Z","timestamp":1794047584075,"version":"4.8.0"},"reference-count":0,"publisher":"Slovenian Chemical Society","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACSi"],"abstract":"<jats:p>This study provides a comprehensive assessment of Ozoroa insignis Delile leaves in terms of their phytochemical, biological, and computational features. The extract showed substantial amounts of alkaloids (57.59 mg\/g), flavonoids (141.48 mg\/g), saponins (61.72 mg\/g), and phenols (142.15 mg\/g). DPPH and H2O2 scavenging activities reached 64.53% and 70.56%, respectively, at a concentration of 50 \u03bcg\/mL. Fraction A showed the strongest inhibition, with the IC50 values of \u03b1-amylase and \u03b1-glucosidase of 53.61 and 78.5 \u03bcg\/mL, respectively. Molecular docking showed that all six GC-MS-identified compounds exhibited binding affinities ranging from \u20134.6 to \u20136.0 kcal\/mol. Overall, O. insignis is considered a promising source of bioactive compounds with antioxidant and enzyme-inhibiting properties for future pharmacological investigation.<\/jats:p>","DOI":"10.17344\/acsi.2025.9205","type":"journal-article","created":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T10:18:08Z","timestamp":1794046688000},"page":"648-660","source":"Crossref","is-referenced-by-count":0,"title":["Phytochemical composition, biological activities, and molecular docking analysis of Ozoroa insignis Delile leaf extracts"],"prefix":"10.17344","volume":"73","author":[{"given":"Abdulkadir","family":"Yunusa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abubakar","family":"Bawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misbahu","family":"Sambo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magret Samuel","family":"Nadro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman Mahmoud","family":"Dogara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ateeq Ahmed","family":"Al-Zahrani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussain Daifallah","family":"Almalki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemn","family":"Star","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7072","published-online":{"date-parts":[[2026,9,25]]},"container-title":["Acta Chimica Slovenica"],"original-title":[],"deposited":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T10:18:16Z","timestamp":1794046696000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.matheo.si\/index.php\/ACSi\/article\/view\/9205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,25]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,9,25]]}},"URL":"https:\/\/doi.org\/10.17344\/acsi.2025.9205","relation":{},"ISSN":["1580-3155"],"issn-type":[{"value":"1580-3155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,25]]}}}