{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T10:58:05Z","timestamp":1775473085435,"version":"3.50.1"},"reference-count":27,"publisher":"Medical Association of Zenica-Doboj","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicinski Glasnik"],"published-print":{"date-parts":[[2019,9,22]]},"abstract":"<jats:p>&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;Aim&amp;lt;br \/&amp;gt;&amp;lt;\/strong&amp;gt; To correlate the maximum anterior sagittal curvature (Kmax) changes and uncorrected (UDVA) and corrected distance visual acuity (CDVA) in keratoconus patients after the cross-linking (CXL) procedure. &amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Methods&amp;lt;br \/&amp;gt;&amp;lt;\/strong&amp;gt;Forty-four eyes of 34 patients with keratoconus were analysed after the standard Dresden protocol CXL procedure had been performed. All patients underwent complete preoperative examination with a follow-up of 12 months with focus on UDVA, CDVA and Oculus Pentacam (Scheimpflug technology) analysis. We analysed and correlated K max changes in the postoperative period of 12 months together with visual acuity changes. &amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Results&amp;lt;br \/&amp;gt;&amp;lt;\/strong&amp;gt; Visual acuity improved significantly in the first 3 months after the procedure and even more significantly until the end of the first year. Even K max is the most relevant and most followed parameter for progression and regression of keratoconus, its lowering was not directly correlated with the visual acuity improvement (both uncorrected and corrected) in the first 6 months after corneal CXL procedure. K max was changed significantly in the period of 12 months post cross linking, but not in the first 6 months. &amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Conclusion&amp;lt;br \/&amp;gt;&amp;lt;\/strong&amp;gt;Corneal CXL should be considered as a procedure not just for corneal stiffening and stabilization, but also for visual acuity improvement in keratoconus patients.&amp;lt;\/p&amp;gt;<\/jats:p>","DOI":"10.17392\/1071-20","type":"journal-article","created":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T10:28:16Z","timestamp":1713695296000},"page":"123-128","source":"Crossref","is-referenced-by-count":4,"title":["Cross-linking treatment for better visual acuity"],"prefix":"10.17392","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7703-7563","authenticated-orcid":false,"given":"Senad","family":"Gri\u0161evi\u0107","sequence":"first","affiliation":[{"name":"Eye Clinic Svjetlost Sarajevo","place":["Sarajevo,Bosnia and Herzegovina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fanka","family":"Gilevska","sequence":"additional","affiliation":[{"name":"Ophthalmology Clinic \u201cSistina Ophthalmology\u201d","place":["Skopje,North Macedonia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alma","family":"Bi\u0161\u010devi\u0107","sequence":"additional","affiliation":[{"name":"Eye Clinic Svjetlost Sarajevo","place":["Sarajevo,Bosnia and Herzegovina"]},{"name":"University Eye Hospital \u2018\u2019Svjetlost\u2019\u2019 Zagreb, School of Medicine University of Rijeka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melisa","family":"Ahmedbegovi\u0107-Pjano","sequence":"additional","affiliation":[{"name":"Eye Clinic Svjetlost Sarajevo","place":["Sarajevo,Bosnia and Herzegovina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajla","family":"Pidro","sequence":"additional","affiliation":[{"name":"Eye Clinic Svjetlost Sarajevo","place":["Sarajevo,Bosnia and Herzegovina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudi","family":"Patel","sequence":"additional","affiliation":[{"name":"NHS National Services Scotland","place":["Edinburgh,United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja","family":"Boha\u010d","sequence":"additional","affiliation":[{"name":"University Eye Hospital \u2018\u2019Svjetlost\u2019\u2019 Zagreb, School of Medicine University of Rijeka"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"49509","published-online":{"date-parts":[[2019,9,22]]},"reference":[{"key":"ref1","first-page":"795738","article-title":"The genetic and environmental factors for keratoconus","author":"AGordon-ShaagA","year":"2015. 2015","unstructured":"Gordon-Shaag A, Millodot M, Shneor E, Liu Y. The \ngenetic and environmental factors for keratoconus. \nBiomed Res Int 2015; 2015:795738.","journal-title":"Biomed Res Int"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.ajo.2016.12.015","article-title":"Age-specific incidence and prevalence of keratoconus: a nationwide registration study","author":"DGodefrooijD","year":"2017","unstructured":"Godefrooij DA, de Wit GA, Uiterwaal CS, Imhof CA, \nWisse RPL. Age-specific incidence and prevalence of \nkeratoconus: a nationwide registration study. Am J \nOphthalmol 2017; 175:169-72.","journal-title":"Am J Ophthalmol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4103\/0974-9233.106379","article-title":"Corneal ectasias: study cohorts and epidemiology","author":"ABialasiewiczA","year":"2013","unstructured":"Bialasiewicz A, Edward DP. Corneal ectasias: stu-\ndy cohorts and epidemiology. Middle East Afr J \nOphthalmol 2013; 20:3-4.","journal-title":"Middle East Afr J Ophthalmol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0002-9394(02)02220-1","article-title":"Riboflavin\/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus","author":"GWollensakG","year":"2003","unstructured":"Wollensak G, Spoerl E, Seiler T. Riboflavin\/ultravio-\nlet-a-induced collagen crosslinking for the treatment \nof keratoconus. Am J Ophthalmol 2003; 135:620-7.","journal-title":"Am J Ophthalmol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1016\/S0886-3350(03)00407-3","article-title":"Stress-strain measurements of human and porcine corneas after riboflavin-ultraviolet-A-induced cross-linking","author":"GWollensakG","year":"2003","unstructured":"Wollensak G, Spoerl E, Seiler T. Stress-strain mea-\nsurements of human and porcine corneas after ribo-\nflavin-ultraviolet-A-induced cross-linking. 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J \nOphthalmol 2017; 2017:4109208.","journal-title":"J Ophthalmol"},{"key":"ref8","first-page":"115","article-title":"The meaning of the demarcation line after riboflavin UVA corneal collagen crosslinking","author":"CMazzottaC","year":"2019","unstructured":"Mazzotta C, Wollensak G, Raiskup F, Pandolfi AM, \nSpoerl E. The meaning of the demarcation line after \nriboflavin UVA corneal collagen crosslinking, Expert \nRev Ophtalmol 2019; 14:115-31.","journal-title":"Expert Rev Ophtalmol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1136\/bjophthalmol-2016-309775","article-title":"Accelerated transepithelial corneal cross-linking for progressive keratoconus: a prospective study of 12 months","author":"WAixinjueluoW","year":"2017","unstructured":"Aixinjueluo W, Usui T, Miyai T, Toyono T, Sakisaka \nT, Yamagami S. Accelerated transepithelial corneal \ncross-linking for progressive keratoconus: a prospec-\ntive study of 12 months. Br J Ophthalmol 2017; 101: \n1244-9.","journal-title":"Br J Ophthalmol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1007\/s00417-018-3966-0","article-title":"Current perspectives on corneal collagen crosslinking (CXL)","author":"SSubasingheS","year":"2018","unstructured":"Subasinghe SK, Ogbuehi KC, Dias GJ. Current per-\nspectives on corneal collagen crosslinking (CXL). \nGraefes Arch Clin Exp Ophthalmol 2018; 256:1363-84.","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"ref11","first-page":"560","article-title":"Corneal collagen cross-linking with riboflavin and ultraviolet A light for pediatric keratoconus: ten-year results","author":"CMazzottaC","year":"2018","unstructured":"Mazzotta C, Traversi C, Baiocchi S, Bagaglia S, Ca-\nporossi O, Villano A, Caporossi A. Corneal collagen \ncross-linking with riboflavin and ultraviolet A light \nfor pediatric keratoconus: ten-year results. Cornea \n2018; 37:560-6.","journal-title":"Cornea"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.ophtha.2013.10.028","article-title":"A randomized, controlled trial of corneal collagen cross-linking in progressive keratoconus: three-year results","author":"CWittig-SilvaC","year":"2014","unstructured":"Wittig-Silva C, Chan E, Islam FM, Wu T, Whiting \nM, Snibson GR. A randomized, controlled trial of \ncorneal collagen cross-linking in progressive kera-\ntoconus: three-year results. Ophthalmology 2014; \n121:812-21.","journal-title":"Ophthalmology"},{"key":"ref13","first-page":"1415","article-title":"Optical performance of the cornea one year following keratoconus treatment with corneal collagen crosslinking","author":"BUysalB","year":"2018","unstructured":"Uysal BS, Sarac O, Yaman D, Akcay E, Cagil N. Op-\ntical performance of the cornea one year following \nkeratoconus treatment with corneal collagen cross-\nlinking. Curr Eye Res 2018; 43:1415-21.","journal-title":"Curr Eye Res"},{"key":"ref14","first-page":"890","article-title":"Pentacam HR criteria for curvature change in keratoconus and postoperative LASIK ectasia","author":"REpsteinR","year":"2012","unstructured":"Epstein RL, Chiu Y, Epstein GL. Pentacam HR crite-\nria for curvature change in keratoconus and postope-\nrative LASIK ectasia. J Refract Surg 2012; 28:890-4.","journal-title":"J Refract Surg"},{"key":"ref15","first-page":"193","article-title":"Correlation between topographic color patterns, keratometric indices, and clinical features among young adults with keratoconus","author":"PPrabhuP","year":"2018","unstructured":"Prabhu PB, Prasannkumary C, Jyothi PT, Babitha V. \nCorrelation between topographic color patterns, kerato-\nmetric indices, and clinical features among young adults \nwith keratoconus. Kerala J Ophthalmol 2018; 30:193-7.","journal-title":"Kerala J Ophthalmol"},{"key":"ref16","first-page":"600","article-title":"Vision-related quality of life in keratoconus: a save sight keratoconus registry study","author":"JckTanJck","year":"2019","unstructured":"Tan JCK, Nguyen V, Fenwick E, Ferdi A, Dinh \nA, Watson SL. Vision-related quality of life in kerato-\nconus: a save sight keratoconus registry study. Cornea \n2019; 38:600-4.","journal-title":"Cornea"},{"key":"ref17","first-page":"459","article-title":"Differences in keratoconus as a function of gender","author":"BFinkB","year":"2005","unstructured":"Fink BA, Wagner H, Steger MK, Rosenstiel C, Roed-\niger T, McMahon TT, Gordon MO, Zadnik K. Differ-\nences in keratoconus as a function of gender. 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Middle East Afr J Ophthalmol \n2015; 22:212-9.","journal-title":"Middle East Afr J Ophthalmol"},{"key":"ref22","first-page":"149","article-title":"Corneal collagen crosslinking for keratoconus and corneal ectasia: oneyear results","author":"PHershP","year":"2011","unstructured":"Hersh PS, Greenstein SA, Fry KL. Corneal collagen \ncrosslinking for keratoconus and corneal ectasia: one-\nyear results. J Cataract Refract Surg 2011; 37:149-60.","journal-title":"J Cataract Refract Surg"},{"key":"ref23","first-page":"385","article-title":"Effects of corneal collagen cross-linking on corneal topographic indices in patients with keratoconus","author":"IToprakI","year":"2013","unstructured":"Toprak I, Yildirim C. Effects of corneal collagen cro-\nss-linking on corneal topographic indices in patients \nwith keratoconus. 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Eye Contact Lens 2014; \n40:335-45.","journal-title":"Eye Contact Lens"}],"container-title":["Medicinski Glasnik"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medicinskiglasnik.ba\/article\/257\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicinskiglasnik.ba\/article\/257\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T09:44:35Z","timestamp":1775468675000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicinskiglasnik.ba\/article\/id\/304\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,22]]},"references-count":27,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,9,22]]},"published-print":{"date-parts":[[2019,9,22]]}},"URL":"https:\/\/doi.org\/10.17392\/1071-20","archive":["Internet Archive"],"relation":{"is-cited-by":[{"id-type":"doi","id":"10.2147\/OPTH.S361836","asserted-by":"object"}]},"ISSN":["1840-0132","1840-0132"],"issn-type":[{"value":"1840-0132","type":"electronic"},{"value":"1840-0132","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9,22]]}}}