{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T10:57:22Z","timestamp":1775473042504,"version":"3.50.1"},"reference-count":20,"publisher":"Medical Association of Zenica-Doboj","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicinski Glasnik"],"published-print":{"date-parts":[[2020,7,12]]},"abstract":"<jats:p>&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;Aim&amp;lt;br \/&amp;gt;&amp;lt;\/strong&amp;gt; To investigate clinical and obstetrical characteristics, an outcome and a prognosis for pregnant women with diagnosed and treated genital or extragenital cancer and their newborns.&amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt; Methods&amp;lt;br \/&amp;gt;&amp;lt;\/strong&amp;gt;This retrospective cohort study included pregnant and childbearing women with a history of cancer diagnosed before pregnancy during the period between 1 January 2014 and 31 December 2018. Data related to the course of pregnancy and childbirth were collected from medical records (mothers&amp;#039; disease history and partogram). The analysis covered clinical and histopathological characteristics of cancers, type of the treatment (surgery, chemotherapy, radiotherapy), demographic data, obstetric characteristics, comorbidities of women, and outcome of the newborns. &amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Results&amp;lt;br \/&amp;gt;&amp;lt;\/strong&amp;gt; The study recorded 18 414 deliveries, of which 30 (0.16%) were pregnancies in women who had been diagnosed and treated earlier for genital or extragenital cancer. The average age of the women at the time of delivery was 29.43&amp;amp;plusmn;5.97 years. There were six (20%) women with genital and 24 (80%) with extragenital cancer. The most frequent extra genital cancer was Hodgkin lymphoma, in eight (26.6%) cases; ovarian cancer was the most frequent genital cancer, in four (13.3%) cases. The average time span from the cancer diagnosis and start of the treatment to the delivery was 59.2&amp;amp;plusmn;44.4 months (5 years) (range 12 months-15 years). Two (6.6%) women died. &amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Conclusion&amp;lt;br \/&amp;gt;&amp;lt;\/strong&amp;gt;Our data demonstrate a favourable obstetric and neonatal outcome for women who have survived cancer.&amp;lt;\/p&amp;gt;<\/jats:p>","DOI":"10.17392\/1109-20","type":"journal-article","created":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T10:28:16Z","timestamp":1713695296000},"page":"457-464","source":"Crossref","is-referenced-by-count":0,"title":["Pregnancy outcome in women who survived genital or extragenital cancer"],"prefix":"10.17392","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7209-382X","authenticated-orcid":false,"given":"Anis","family":"Cerovac","sequence":"first","affiliation":[{"name":"General Hospital Te\u0161anj","place":["Te\u0161anj,Bosnia and Herzegovina"],"department":["Department of Gynaecology and Obstetrics"]},{"name":"University of Tuzla","place":["Tuzla,Bosnia and Herzegovina"],"department":["Department of Anatomy, School of Medicine"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u017eenita","family":"Ljuca","sequence":"additional","affiliation":[{"name":"Clinic for Gynaecology and Obstetrics, University Clinical Centre Tuzla","place":["Tuzla,Bosnia and Herzegovina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordana","family":"Bogdanovi\u0107","sequence":"additional","affiliation":[{"name":"Clinic for Gynaecology and Obstetrics, University Clinical Centre Tuzla","place":["Tuzla,Bosnia and Herzegovina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordana","family":"Grgi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haris","family":"Zuki\u0107","sequence":"additional","affiliation":[{"name":"Clinic for Gynaecology and Obstetrics, University Clinical Centre Tuzla","place":["Tuzla,Bosnia and Herzegovina"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"49509","published-online":{"date-parts":[[2020,7,12]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1080\/01443615.2017.1318265","article-title":"Pregnancy in cancer patients and survivors; experience of a university hospital in Turkey","author":"Al\u0131c\u0131Davuto\u011fluAl\u0131c\u0131","year":"2017","unstructured":"Al\u0131c\u0131 Davuto\u011flu E, Madazl\u0131 R, Y\u0131lmaz N, Ozel A, \nUludag S, Sozen I. Pregnancy in cancer patients and \nsurvivors; experience of a university hospital in Tur-\nkey. J Obstet Gynaecol 2017; 37:1015-9.","journal-title":"J Obstet Gynaecol"},{"key":"ref2","first-page":"849","article-title":"Obstetric outcomes in cancer survivors","author":"HClarkH","year":"2007","unstructured":"Clark H, Kurinczuk JJ, Lee AJ, Bhattacharya S. Ob-\nstetric outcomes in cancer survivors. Obstet Gyne-\ncol. 2007; 110:849-54.","journal-title":"Obstet Gynecol"},{"key":"ref3","first-page":"765","article-title":"Perinatal considerations in women with previous diagnosis of cancer","author":"ALandaA","year":"2015","unstructured":"Landa A, Kuller J, Rhee E. Perinatal considerations \nin women with previous diagnosis of cancer. Obstet \nGynecol Surv 2015; 70:765-72.","journal-title":"Obstet Gynecol Surv"},{"key":"ref4","first-page":"35","article-title":"Cancer during pregnancy -clinical characteristics, treatment outcomes and prognosis for mothers and infants","author":"KJeremicK","year":"2018","unstructured":"Jeremic K, Stefanovic A, Dotlic J, Kadija S, Kontic \nO, Gojnic M, Jeremic J, Kesic V. Cancer during pre-\ngnancy -clinical characteristics, treatment outco-\nmes and prognosis for mothers and infants. J Perinat \nMed 2018; 46:35-45.","journal-title":"J Perinat Med"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1002\/ijc.26045","article-title":"Pregnancy after adolescent and adult cancer: a population-based matched cohort study","author":"HStensheimH","year":"2011","unstructured":"Stensheim H, Cvancarova M, M\u00f8ller B, Foss\u00e5 SD. \nPregnancy after adolescent and adult cancer: a po-\npulation-based matched cohort study. Int J Cancer \n2011; 129:1225-36.","journal-title":"Int J Cancer"},{"key":"ref6","first-page":"269","article-title":"Reproductive outcomes following treatment for a gynecological cancer diagnosis: a systematic review","author":"BGerstlB","year":"2019","unstructured":"Gerstl B, Sullivan E, Vallejo M, Koch J, Johnson M, \nWand H, Webber K, Ives A, Anazodo A. Reproducti-\nve outcomes following treatment for a gynecological \ncancer diagnosis: a systematic review. J Cancer Sur-\nviv 2019; 13:269-81.","journal-title":"J Cancer Surviv"},{"key":"ref7","first-page":"4451","article-title":"Reproductive outcomes following a stem cell transplant for a haematological malignancy in female cancer survivors: a systematic review and meta-analysis","author":"BGerstlB","year":"2019","unstructured":"Gerstl B, Sullivan E, Koch J, Wand H, Ives A, \nMitchell R, Hamad N, Anazodo A. Reproductive \noutcomes following a stem cell transplant for a hae-\nmatological malignancy in female cancer survivors: \na systematic review and meta-analysis. Support Care \nCancer 2019; 27:4451-60.","journal-title":"Support Care Cancer"},{"key":"ref8","first-page":"479","article-title":"A systematic review examining the effects of therapeutic radioactive iodine on ovarian function and future pregnancy in female thyroid cancer survivors","author":"ASawkaA","year":"2008","unstructured":"Sawka AM, Lakra DC, Lea J, Alshehri B, Tsang RW, \nBrierley JD, Straus S, Thabane L, Gafni A, Ezzat S, \nGeorge SR, Goldstein DP. A systematic review exa-\nmining the effects of therapeutic radioactive iodine \non ovarian function and future pregnancy in fema-\nle thyroid cancer survivors. 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Int J Radiat \nOncol Biol Phys 2012; 84:755-61.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref14","first-page":"1179","article-title":"Impact of pregnancy on outcome and prognosis of survivors of papillary thyroid cancer","author":"DHirschD","year":"2010","unstructured":"Hirsch D, Levy S, Tsvetov G, Weinstein R, Lifshitz \nA, Singer J, Shraga-Slutzky I, Grozinski-Glasberg \nS, Shimon I, Benbassat C. Impact of pregnancy on \noutcome and prognosis of survivors of papillary \nthyroid cancer. Thyroid 2010; 20:1179-85.","journal-title":"Thyroid"},{"key":"ref15","first-page":"6941","article-title":"Lack of influence of pregnancy on the prognosis of survivors of thyroid cancer","author":"ABudakA","year":"2013","unstructured":"Budak A, Gulhan I, Aldemir OS, Ileri A, Tekin E, \nOzeren M. Lack of influence of pregnancy on the \nprognosis of survivors of thyroid cancer. Asian Pac J \nCancer Prev 2013; 14:6941-3.","journal-title":"Asian Pac J Cancer Prev"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1007\/s11764-018-0707-7","article-title":"Reproductive and gynecological complication risks among thyroid cancer survivors","author":"BBlackburnB","year":"2018","unstructured":"Blackburn BE, Ganz PA, Rowe K, Snyder J, Wan Y, \nDeshmukh V, Newman M, Fraser A, Smith K, Her-\nget K, Kim J, Kirchhoff AC, Porucznik C, Hanson H, \nAbraham D, Monroe M, Hashibe M. Reproductive \nand gynecological complication risks among thyroid \ncancer survivors. J Cancer Surviv 2018; 12:702-11.","journal-title":"J Cancer Surviv"},{"key":"ref17","first-page":"2187","article-title":"The risk of preterm birth and growth restriction in pregnancy after cancer","author":"KHartnettK","year":"2017","unstructured":"Hartnett KP, Ward KC, Kramer MR, Lash TL, Mer-\ntens AC, Spencer JB, Fothergill A, Howards PP .The \nrisk of preterm birth and growth restriction in pre-\ngnancy after cancer. Int J Cancer 2017; 141:2187-96.","journal-title":"Int J Cancer"},{"key":"ref18","first-page":"136","article-title":"Premature and preterm premature rupture of membranes in adolescent compared to adult pregnancy","author":"SMarkovi\u0107S","year":"2020","unstructured":"Markovi\u0107 S, Bogdanovi\u0107 G, Cerovac A. Prematu-\nre and preterm premature rupture of membranes in \nadolescent compared to adult pregnancy. Med Glas \n(Zenica) 2020; 17:136-40.","journal-title":"Med Glas (Zenica)"},{"key":"ref19","first-page":"160","article-title":"ESMO Guidelines Working Group. Cancer, pregnancy and fertility: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up","author":"FPeccatoriF","year":"2013","unstructured":"Peccatori FA , Azim HA Jr, Orecchia R, Hoekstra \nHJ, Pavlidis N, Kesic V, Pentheroudakis G; ESMO \nGuidelines Working Group. Cancer, pregnancy and \nfertility: ESMO Clinical Practice Guidelines for di-\nagnosis, treatment and follow-up. Ann Oncol 2013; \n24:vi160-70.","journal-title":"Ann Oncol"},{"key":"ref20","first-page":"873","article-title":"Infertility, infertility treatment, and achievement of pregnancy in female survivors of childhood cancer: a report from the Childhood Cancer Survivor Study cohort","author":"SBartonS","year":"2013","unstructured":"Barton SE , Najita JS, Ginsburg ES, Leisenring WM, \nStovall M, Weathers RE, Sklar CA, Robison LL, \nDiller L. Infertility, infertility treatment, and achie-\nvement of pregnancy in female survivors of childho-\nod cancer: a report from the Childhood Cancer Sur-\nvivor Study cohort. 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