{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:03:00Z","timestamp":1790420580545,"version":"4.1.0"},"reference-count":18,"publisher":"Medical Association of Zenica-Doboj","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicinski Glasnik"],"published-print":{"date-parts":[[2020,10,9]]},"abstract":"<jats:p>&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;Aim&amp;lt;\/strong&amp;gt; &amp;lt;br \/&amp;gt;To investigate the changes in the value of the signal to noise ratio (SNR) and to assess changes in the expression of nuclear factor erythroid 2-related factor 2 (NRF2) in the organ of Corti of rat exposed to noise.&amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Methods&amp;lt;\/strong&amp;gt; &amp;lt;br \/&amp;gt;This study used a randomized post test only control group laboratory experimental design with 27 male Wistar strain Rattus norvegicus. The study group was divided into 3 groups (n = 9): group I (control), group 2 (2 hours of 100 dB noise exposure) and group 3 (2 hours of 110 dB noise exposure).&amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Results&amp;lt;\/strong&amp;gt; &amp;lt;br \/&amp;gt;There was no significant difference in the SNR in the group 1 on day 0, 2 and 4 (p&amp;amp;gt;0.05). However, there was a significant&amp;lt;br \/&amp;gt;difference in the SNR in the group 2 and the group 3 on day 0, 2 and 4 (p&amp;amp;lt;0.05). There was a significant difference in the mean levels of NRF2 expression in the cochlear organ of Rattus norvegicus in all groups (p&amp;amp;lt;0.05). There was no correlation between the SNR and the NRF2 expression in group 2 (p&amp;amp;gt; 0.05), but there was a correlation between the SNR and the NRF2 expression in the group 3 (p&amp;amp;lt;0.05).&amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Conclusion&amp;lt;\/strong&amp;gt; &amp;lt;br \/&amp;gt;There was found a correlation between the SNR value on distortion product otoacoustic emission (DPOAE) examination&amp;lt;br \/&amp;gt;and NRF2 expression in the cochlear organ of Corti of Rattus norvegicus exposed to 110 dB noise.&amp;lt;\/p&amp;gt;<\/jats:p>","DOI":"10.17392\/1292-21","type":"journal-article","created":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T10:28:16Z","timestamp":1713695296000},"page":"102-106","source":"Crossref","is-referenced-by-count":1,"title":["Correlation of signal to noise ratio (SNR) value on distortion product otoacoustic emission (DPOAE) and expression of nuclear factor erythroid 2-related factor 2 (NRF2) in cochlear organ of Corti in rat exposed to noise"],"prefix":"10.17392","volume":"18","author":[{"given":"Diana","family":"Amellya","sequence":"first","affiliation":[{"name":"Universitas Sumatera Utara","department":["Department of Otolaryngology, Head and Neck Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9984-6166","authenticated-orcid":false,"given":"Tengku Siti","family":"Hajar Haryuna","sequence":"additional","affiliation":[{"name":"Universitas Sumatera Utara","department":["Department of Otolaryngology, Head and Neck Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wibi","family":"Riawan","sequence":"additional","affiliation":[{"name":"Brawijaya University","department":["Department of Biochemistry and Molecular Biology"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"49509","published-online":{"date-parts":[[2020,10,9]]},"reference":[{"key":"ref1","first-page":"1325","article-title":"Auditory and non-auditory effects of noise on health","author":"MBasnerM","year":"2014","unstructured":"Basner M, Babisch W, Davis A, Brink M, Clark C, \nJanssen S, Stansfeld S. 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Nitric Oxide \n2011; 25:153-60.","journal-title":"Nitric Oxide"}],"container-title":["Medicinski Glasnik"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medicinskiglasnik.ba\/article\/298\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicinskiglasnik.ba\/article\/298\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T09:43:58Z","timestamp":1775468638000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicinskiglasnik.ba\/article\/id\/175\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,9]]},"references-count":18,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,10,9]]},"published-print":{"date-parts":[[2020,10,9]]}},"URL":"https:\/\/doi.org\/10.17392\/1292-21","archive":["Internet Archive"],"relation":{},"ISSN":["1840-0132","1840-0132"],"issn-type":[{"value":"1840-0132","type":"electronic"},{"value":"1840-0132","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10,9]]}}}